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Review Article

纤维素基材料在持续给药系统中的应用

卷 26, 期 14, 2019

页: [2485 - 2501] 页: 17

弟呕挨: 10.2174/0929867324666170705143308

价格: $65

摘要

生物相容的，可生物降解的和生物可利用的赋形剂对于药物递送系统是至关重要的。 纤维素及其衍生物基赋形剂由于其绿色/天然和独特的包封/结合特性而得到了充分研究。 它们通常用于受控/持续的药物递送系统。 在这些应用中，纤维素及其衍生物的功能通常可以改变药物的溶解度/胶凝行为，从而产生控制药物释放曲线的不同机制。 本文简要回顾了目前常规纤维素衍生物的结构和化学知识及其在药物传递系统中的应用。 还讨论了在持续药物递送的应用中开发创新的基于纤维素的材料，包括微纤维素（MC）和纳米纤维素（NC）。

关键词: 纤维素及其衍生物，生物利用度，赋形剂，药物递送系统，生物相容性，可生物降解，纤维素基材料。

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