Abstract
Dimedone (5,5-dimethylcyclohexane-1,3-dione) is an alicyclic diketone, occasionally considered as building blocks in design and synthesis of a wide variety of heterocycles. The synthetic efficacy of dimedone as a synthon has been presented as a chapter in Advances in Heterocyclic Chemistry in 2009. Due to importance of dimedone and huge numbers of cited references concerning its applications after 2009 till date, in this review we try to update its unique role as a privileged synthon in the synthesis of different heterocyclic compounds.
Keywords: Dimedone, heterocycles, multicomponent reaction, alicyclic diketone.
Graphical Abstract
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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