氧化铁纳米颗粒：了解他们的生物医学应用

Title:Iron Oxide Nanoparticles: An Insight into their Biomedical Applications

Volume: 22 Issue: 15

Author(s): Diana Couto, Marisa Freitas, Felix Carvalho and Eduarda Fernandes

Affiliation:

关键词: 生物分布，生物医学应用，涂层，内化路径，氧化铁纳米颗粒， 毒性

摘要: Iron oxide nanoparticles (IONs) are among the most common types of nanoparticles (NPs) used in biomedical applications. IONs can be presented in different forms [e.g. magnetite (Fe₃O₄), hematite (α-Fe₂O₃) and maghemite (γ- Fe₂O₃)], and are usually coated with substances and/or polymers according to the purpose for which they are intended to be used. In recent years, IONs use has been increasing exponentially in many fields of biomedicine, namely in magnetic resonance imaging, cell sorting, tissue repair, induction of hyperthermia and drug delivery, among others. This review aims to provide an update on the different IONs and the substances and/or polymers that can be used to coat the IONs core as well as their applications and biological properties, namely their biodistribution in the human body and their cellular internalization pathways.

Cite this article as:

Diana Couto, Marisa Freitas, Felix Carvalho and Eduarda Fernandes , Iron Oxide Nanoparticles: An Insight into their Biomedical Applications, Current Medicinal Chemistry 2015; 22 (15) . https://dx.doi.org/10.2174/0929867322666150311151403