Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes

Title:Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes

Volume: 14 Issue: 10

Author(s): Carmen Nejera and Jose M. Sansano

Affiliation:

Keywords: Antitumoral, asymmetric synthesis, catalysis, cycloaddition, metal, organocatalyst.

Abstract: This review highlights the biological importance of many polysubstituted nitro-prolines and -pyrrolidines. Their preparation using asymmetric 1,3-dipolar cycloadditions of azomethine ylides with nitroalkenes using diastereoselective and enantioselective strategies is described remarking the scope and main features of each one.

Cite this article as:

Nejera Carmen and Sansano M. Jose, Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes, Current Topics in Medicinal Chemistry 2014; 14 (10) . https://dx.doi.org/10.2174/1568026614666140423112145