Synthesis, Spectroscopic and Structural Studies of New 2-Substituted 4- Nitroimidazoles

Title:Synthesis, Spectroscopic and Structural Studies of New 2-Substituted 4- Nitroimidazoles

Volume: 11 Issue: 3

Author(s): Hayette Alliouche, Abdelmalek Bouraiou, Sofiane Bouacida, Mebarek Bahnous, Thierry Roisnel and Ali Belfaitah

Affiliation:

Keywords: Transposition reaction, 4-nitroimidazole, 5-nitroimidazole, crystal structure.

Abstract: This study describes the synthesis of novel 4-nitro-2-substitutedimidazole derivatives via a transposition reaction of nitro group. Conversion of 5-nitro-2-phenylethanol (styryl) imidazole derivatives into the corresponding 4- nitroisomers was achieved in good yields in nitrobenzene using a catalytic amount of methyl iodide. Spectroscopic study and single crystal X-ray structures are reported for five compounds to understand the conformational structures of these compounds.

Cite this article as:

Alliouche Hayette, Bouraiou Abdelmalek, Bouacida Sofiane, Bahnous Mebarek, Roisnel Thierry and Belfaitah Ali, Synthesis, Spectroscopic and Structural Studies of New 2-Substituted 4- Nitroimidazoles, Letters in Organic Chemistry 2014; 11 (3) . https://dx.doi.org/10.2174/15701786113106660090