Currently Used Antimycotics: Spectrum, Mode of Action and Resistance Occurrence

Title: Currently Used Antimycotics: Spectrum, Mode of Action and Resistance Occurrence

Volume: 6 Issue: 8

Author(s): Isabelle E.J.A. Francois, An M. Aerts, Bruno P.A. Cammue and Karin Thevissen

Affiliation:

Keywords: Griseofulvin, 5-FC, echinocandins, allylamines, polyenes, azoles

Abstract: The increasing incidence of fungal infections combined with the emerging problem of antifungal drug resistance have prompted investigations of the mode of action of the currently used antifungal therapeutics (antimycotics). The routinely used antimycotics can be grouped into six different classes based on their mode of action. In this review, the mode of action and antifungal spectrum of these classes are discussed, together with possible resistance development against them.

Cite this article as:

Francois E.J.A. Isabelle, Aerts M. An, Cammue P.A. Bruno and Thevissen Karin, Currently Used Antimycotics: Spectrum, Mode of Action and Resistance Occurrence, Current Drug Targets 2005; 6 (8) . https://dx.doi.org/10.2174/138945005774912744