Application of Microfluidic Technology for Studying Islet Physiology and Pathophysiology

Title:Application of Microfluidic Technology for Studying Islet Physiology and Pathophysiology

Volume: 5 Issue: 3

Author(s): Yong Wang, Joshua E. Mendoza-Elias, James J. McGarrigle, Mohammad Nourmohammadzadeh, Qian Wang, Ze Li, Brian Rady, Feng Feng, Meirigeng Qi, Joe F. Lo, David T. Eddington and Jose Oberholzer

Affiliation:

Keywords: β-cells, Insulin Secretion, Islet of Langerhans, Microencapsulation, Microfluidics, Oxygen, Transplantation.

Abstract: This review outlines the current status of microfluidic devices used to study the physiology and pathophysiology of pancreatic islets of Langerhans, mainly focusing on the design features and specialized applications of existing microfluidic devices, as well as their advantages and limitations. This review then briefly concludes by describing future perspectives on ways to improve and implement microfluidic technology for islet study.

Cite this article as:

Wang Yong, Mendoza-Elias E. Joshua, McGarrigle J. James, Nourmohammadzadeh Mohammad, Wang Qian, Li Ze, Rady Brian, Feng Feng, Qi Meirigeng, Lo F. Joe, Eddington T. David and Oberholzer Jose, Application of Microfluidic Technology for Studying Islet Physiology and Pathophysiology, Micro and Nanosystems 2013; 5 (3) . https://dx.doi.org/10.2174/1876402911305030009