Abstract
Electrochemical oxidation of 4–methylesculetin has been studied in the presence of arylsulfinic acids as nucleophiles in aqueous/ acetonitrile solution mixture, using cyclic voltammetry and controlled-potential coulometry. The results indicate that the o-quinone derived from oxidation of 4–methylesculetin undergoes a 1,6–Michael addition reaction with unique selectivity, converts to the corresponding new sulfone derivative of esculetin. The reaction products were derived with good yields and excellent selectivity based on electrochemical oxidation under controlled potential conditions at a carbon electrode in an undivided cell.
Keywords: 4-Methylesculetin, 1, 6-Michael addition, arylsulfinic acids, cyclic voltammetry, electrochemical synthesis.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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