Abstract
In recent years, pharmaceutical chemists have synthesized large numbers of andrographolide derivatives, which bear important biological activities such as anti-inflammatory, antibacterial, antivirus, antitumor, antidiabetic, and antifeedant. Consequently, corresponding SARs were increasingly obvious. This paper aimed to review all the available literature in this field, highlighting the significant achievements on the structural modification and SARs of andrographolide and its derivatives.
Keywords: Andrographolide derivatives, biological activities, SARs
Mini-Reviews in Medicinal Chemistry
Title:Biological Activities and Corresponding SARs of Andrographolide and Its Derivatives
Volume: 13 Issue: 2
Author(s): Bin Zhou, Dayong Zhang and Xiaoming Wu
Affiliation:
Keywords: Andrographolide derivatives, biological activities, SARs
Abstract: In recent years, pharmaceutical chemists have synthesized large numbers of andrographolide derivatives, which bear important biological activities such as anti-inflammatory, antibacterial, antivirus, antitumor, antidiabetic, and antifeedant. Consequently, corresponding SARs were increasingly obvious. This paper aimed to review all the available literature in this field, highlighting the significant achievements on the structural modification and SARs of andrographolide and its derivatives.
Export Options
About this article
Cite this article as:
Zhou Bin, Zhang Dayong and Wu Xiaoming, Biological Activities and Corresponding SARs of Andrographolide and Its Derivatives, Mini-Reviews in Medicinal Chemistry 2013; 13 (2) . https://dx.doi.org/10.2174/1389557511313020011
DOI https://dx.doi.org/10.2174/1389557511313020011 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Computer-Aided Drug Design Applied to Secondary Metabolites as Anticancer Agents
Current Topics in Medicinal Chemistry The Connections Among Autophagy, Inflammasome and Mitochondria
Current Drug Targets Inducible Nitric Oxide Synthase-Vascular Endothelial Growth Factor Axis: A Potential Target to Inhibit Tumor Angiogenesis by Dietary Agents
Current Cancer Drug Targets Stathmin, Interacting with Nf-κB, Promotes Tumor Growth and Predicts Poor Prognosis of Pancreatic Cancer
Current Molecular Medicine Molecular Dynamics and Biological Evaluation of 2-chloro-7-cyclopentyl- 7H-pyrrolo[2,3-d]pyrimidine Derivatives Against Breast Cancer
Combinatorial Chemistry & High Throughput Screening 99mTc-(tricine)-HYNIC-Lys-FROP Peptide for Breast Tumor Targeting
Anti-Cancer Agents in Medicinal Chemistry New Approaches to the Modulation of the Cyclooxygenase-2 and 5-Lipoxygenase Pathways
Current Topics in Medicinal Chemistry The CLCA Gene Family A Novel Family of Putative Chloride Channels
Current Genomics Berberine Administration in Treatment of Colitis: A Review
Current Drug Targets Calcium Phosphate System for Gene Delivery: Historical Background and Emerging Opportunities
Current Pharmaceutical Design Current Protein-based Anti-angiogenic Therapeutics
Mini-Reviews in Medicinal Chemistry Cell Metabolism Under Microenvironmental Low Oxygen Tension Levels in Stemness, Proliferation and Pluripotency
Current Molecular Medicine Antitumorigenic Effect of Memantine via Interfering Glutamate Metabolism in Mouse 4T1 Breast Tumor Model
Anti-Cancer Agents in Medicinal Chemistry Cartilage Oligomeric Matrix Protein: Matricellular and Matricrine Signaling in Cardiovascular Homeostasis and Disease
Current Vascular Pharmacology CDC25 Inhibitors as Anticancer Agents Are Moving Forward
Anti-Cancer Agents in Medicinal Chemistry Gene Profile Identifies Zinc Transporters Differentially Expressed in Normal Human Organs and Human Pancreatic Cancer
Current Molecular Medicine The Pathophysiological Role of PEDF in Bone Diseases
Current Molecular Medicine Overactive Bladder - Current Treatment Modalities
Current Women`s Health Reviews Diabetic Gastroenteropathy: Soothe the Symptoms or Unravel a Cure?
Current Diabetes Reviews Anti-Cytokine Therapeutics: History and Update
Current Pharmaceutical Design