Perspectives on the Development of Novel Potentially Active Quinolones Against Tuberculosis and Cancer

Title:Perspectives on the Development of Novel Potentially Active Quinolones Against Tuberculosis and Cancer

Volume: 12 Issue: 9

Author(s): V. Facchinetti, C. R.B. Gomes, M. V.N. de Souza and T. R.A. Vasconcelos

Affiliation:

Keywords: Biological activity, cancer, drugs, quinolones, tuberculosis, iodoanilines, BCG, Ciprofloxacin, in vitro, 6-nitroquinolones

Abstract: Quinolones and its derivatives comprise an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as antibacterial, antitumor, antiviral, anti-ischemic, antiparasitic and anxiolytic. Persistent efforts have been made over the years to develop novel congeners with superior biological activities and minimal potential for undesirable side-effects. The present review aims to highlight some recent discoveries on the development of novel quinolone-based compounds with potential antitubercular and anticancer activity.

Cite this article as:

Facchinetti V., R.B. Gomes C., V.N. de Souza M. and R.A. Vasconcelos T., Perspectives on the Development of Novel Potentially Active Quinolones Against Tuberculosis and Cancer, Mini-Reviews in Medicinal Chemistry 2012; 12 (9) . https://dx.doi.org/10.2174/138955712800959099