Synthesis, Characterisation, Anti-Microbial Activity and Docking Studies of Novel Dispiro- Oxindolopyrrolidines

Title: Synthesis, Characterisation, Anti-Microbial Activity and Docking Studies of Novel Dispiro- Oxindolopyrrolidines

Volume: 2 Issue: 3

Author(s): Adukamparai R.S. Babu, Raghavachary Raghunathan, Narayanasamy Mathivanan, Gurusamy Omprabhac, Devadasan Velmurugan and Rangasamy Raghu

Affiliation:

Keywords: 1,3-Dipolar cycloaddition, azomethine ylide, spiro-pyrrolidines, spiro-oxindolopyrrolidine, anti-microbial activity, 30S ribosomal subunit

Abstract: A facile synthesis and characterisation of novel dispiro-oxindolopyrrolidines is delineated. The results of the anti-microbial studies of novel dispiro-oxindolopyrrolidines are correlated with the docking calculations performed on protein S12 from 30S ribosomal subunit.

Cite this article as:

Babu R.S. Adukamparai, Raghunathan Raghavachary, Mathivanan Narayanasamy, Omprabhac Gurusamy, Velmurugan Devadasan and Raghu Rangasamy, Synthesis, Characterisation, Anti-Microbial Activity and Docking Studies of Novel Dispiro- Oxindolopyrrolidines, Current Chemical Biology 2008; 2 (3) . https://dx.doi.org/10.2174/2212796810802030312