Abstract
Carnitine is well-known for its role in the transport of fatty acids to the mitochondrial matrix, where β- oxidation takes place. This work describes novel functions for this compound and novel data on its pharmacokinetics.
Keywords: Carnitine, acetyl-L-carnitine, free radicals, apoptosis, acetylation
Mini-Reviews in Medicinal Chemistry
Title: Involvement of L-Carnitine in Cellular Metabolism: Beyond Acyl-CoA Transport
Volume: 9 Issue: 13
Author(s): S. P. Chapela, N. Kriguer, E. H. Fernandez and C. A. Stella
Affiliation:
Keywords: Carnitine, acetyl-L-carnitine, free radicals, apoptosis, acetylation
Abstract: Carnitine is well-known for its role in the transport of fatty acids to the mitochondrial matrix, where β- oxidation takes place. This work describes novel functions for this compound and novel data on its pharmacokinetics.
Export Options
About this article
Cite this article as:
Chapela P. S., Kriguer N., Fernandez H. E. and Stella A. C., Involvement of L-Carnitine in Cellular Metabolism: Beyond Acyl-CoA Transport, Mini-Reviews in Medicinal Chemistry 2009; 9 (13) . https://dx.doi.org/10.2174/138955709790361502
DOI https://dx.doi.org/10.2174/138955709790361502 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The cAMP-Dependent Protein Kinase Pathway as Therapeutic Target – Possibilities and Pitfalls
Current Topics in Medicinal Chemistry Relevance of Multidrug Resistance Proteins on the Clinical Efficacy of Cancer Therapy
Current Drug Delivery Effect of miR-128 in DNA Damage of HL-60 Acute Myeloid Leukemia Cells
Current Pharmaceutical Biotechnology The Microarray Gene Profiling Analysis of Glioblastoma Cancer Cells Reveals Genes Affected by FAK Inhibitor Y15 and Combination of Y15 and Temozolomide
Anti-Cancer Agents in Medicinal Chemistry Reversal of Resistance to Oxazaphosphorines
Current Cancer Drug Targets The Path from Anti Parkinson Drug Selegiline and Rasagiline to Multifunctional Neuroprotective Anti Alzheimer Drugs Ladostigil and M30
Current Alzheimer Research Contemporary Anticholinesterase Pharmaceuticals of Natural Origin and Their Synthetic Analogues for the Treatment of Alzheimers Disease
Recent Patents on CNS Drug Discovery (Discontinued) Estrogen Receptor Signaling: Impact on Cell Functions
Current Signal Transduction Therapy The Potential of Statins for Individualized Colorectal Cancer Chemoprevention
Current Drug Targets DREADD in Parvalbumin Interneurons of the Dentate Gyrus Modulates Anxiety, Social Interaction and Memory Extinction
Current Molecular Medicine Idiotype Vaccines for Human B-Cell Malignancies
Current Pharmaceutical Design Overview of Brain Tumor Stem Cells – Implications for Treatment
Current Signal Transduction Therapy Cellular and Biochemical Actions of Melatonin which Protect Against Free Radicals: Role in Neurodegenerative Disorders
Current Neuropharmacology Hypoglycemia Induces Tau Hyperphosphorylation
Current Alzheimer Research Involvement of Membrane Channels in Autoimmune Disorders
Current Pharmaceutical Design Anti-Angiogenic Peptides for Cancer Therapeutics
Current Pharmaceutical Biotechnology Hijacking the Hedgehog Pathway in Cancer Therapy
Anti-Cancer Agents in Medicinal Chemistry A Novel µ-Opioid Receptor Ligand with High In Vitro and In Vivo Agonist Efficacy
Current Medicinal Chemistry Erythropoietin and Oxidative Stress
Current Neurovascular Research Tetracyclines and Prion Infectivity
Infectious Disorders - Drug Targets