Abstract
The synthesis of 1,3-diphenyl-5-arylpyrazoles via the reactions of 2,3-epoxy-1-phenyl-3-aryl-1-propanones with phenylhydrazine was carried out in 48-84% yields at 230 °C under solvent-free condition within 1.5 h. This method provides several advantages such as operational simplicity, higher yield and solvent-free.
Keywords: cyclization, 1,3-diphenyl-5-arylpyrazole, synthesis, solvent-free reaction, heterocycles
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