Ultrasound Irradiation Promoted Large-Scale Preparation in Aqueous Media and Antioxidant Activity of Azoles

Title: Ultrasound Irradiation Promoted Large-Scale Preparation in Aqueous Media and Antioxidant Activity of Azoles

Volume: 6 Issue: 5

Author(s): F. A.N. Silva, M. P. Galluzzi, B. Albuquerque, L. Pizzuti, V. Gressler, D. P. Rivelli, S. B.M. Barros and C. M.P. Pereira

Affiliation:

Keywords: Green chemistry, Isoxazole, Pyrazole, Sonocatalysis, ORAC, DPPH

Abstract: The scaled-up preparation of 1H-pyrazole, 1-phenylpyrazole and isoxazole via sonocatalysis is reported. The products were isolated in good yields in short time reaction. These compounds had been assayed for antioxidant activity by ORAC and DPPH methodologies. The results showed that only 1-phenylpyrazole presented good antioxidant activity compared with Trolox .

Cite this article as:

Silva A.N. F., Galluzzi P. M., Albuquerque B., Pizzuti L., Gressler V., Rivelli P. D., Barros B.M. S. and Pereira M.P. C., Ultrasound Irradiation Promoted Large-Scale Preparation in Aqueous Media and Antioxidant Activity of Azoles, Letters in Drug Design & Discovery 2009; 6 (5) . https://dx.doi.org/10.2174/1570180810906050323

DOI https://dx.doi.org/10.2174/1570180810906050323	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X