A Method for the Syntheses of Enopyranosides

Khalid   M.   Khan; Shahnaz      Perveen; Raed   A.S.   Al-Qawasmeh; Mohammed   S.   Shekhani; Syed   T.   Ali Shah; Wolfgang      Voelter

doi:10.2174/157017809787893109

Abstract

Sodium hydride (NaH) in hexamethylphosphoric triamide (HMPA) has been introduced as an economical and efficient reagent towards the creation of 1,2- or 5,6-enopyranosides from the corresponding halogenated or tosylated pyranosides. NaH/HMPA has several advantages compared to NaH/DMF: elimination products are produced in high yields even from sterically-hindered halides as well as tosylates.

Keywords: Enopyranosides, sodium hydride/hexamethylphosphoric triamide, carbohydrates

« Previous Next »

Rights & Permissions Print Cite

Letters in Organic Chemistry

Title: A Method for the Syntheses of Enopyranosides

Volume: 6 Issue: 3

Author(s): Khalid M. Khan, Shahnaz Perveen, Raed A.S. Al-Qawasmeh, Mohammed S. Shekhani, Syed T. Ali Shah and Wolfgang Voelter

Affiliation:

Keywords: Enopyranosides, sodium hydride/hexamethylphosphoric triamide, carbohydrates

Abstract: Sodium hydride (NaH) in hexamethylphosphoric triamide (HMPA) has been introduced as an economical and efficient reagent towards the creation of 1,2- or 5,6-enopyranosides from the corresponding halogenated or tosylated pyranosides. NaH/HMPA has several advantages compared to NaH/DMF: elimination products are produced in high yields even from sterically-hindered halides as well as tosylates.

Export Options

Export File:

RIS (for EndNote, Reference Manager, ProCite)

BibTeX

Text

Content:

Citation Only

Citation and Abstract

About this article

Cite this article as:

Khan M. Khalid, Perveen Shahnaz, Al-Qawasmeh A.S. Raed, Shekhani S. Mohammed, Ali Shah T. Syed and Voelter Wolfgang, A Method for the Syntheses of Enopyranosides, Letters in Organic Chemistry 2009; 6 (3) . https://dx.doi.org/10.2174/157017809787893109