Excellent Exo/Endo-Selectivity in the 1,3-Dipolar Cycloaddition of Cyclic Azomethine Ylide: Exploring the Facile Investigation of Cocaine Antagonists

Title: Excellent Exo/Endo-Selectivity in the 1,3-Dipolar Cycloaddition of Cyclic Azomethine Ylide: Exploring the Facile Investigation of Cocaine Antagonists

Volume: 4 Issue: 8

Author(s): Joydev K. Laha

Affiliation:

Keywords: Cocaine antagonists, tropane, 1,3-dipolar cycloaddition, cyclic azomethine ylide, exo/endo-selectivity

Abstract: High exo-selectivity was achieved in the 1,3-dipolar cycloaddition of a cyclic azomethine ylide and phenyl vinyl sulfone or Opplozers camphorsultam chiral dipolarophile leading to the synthesis of two novel tropane compounds.

Cite this article as:

Laha K. Joydev, Excellent Exo/Endo-Selectivity in the 1,3-Dipolar Cycloaddition of Cyclic Azomethine Ylide: Exploring the Facile Investigation of Cocaine Antagonists, Letters in Organic Chemistry 2007; 4 (8) . https://dx.doi.org/10.2174/157017807782795448