Abstract
High exo-selectivity was achieved in the 1,3-dipolar cycloaddition of a cyclic azomethine ylide and phenyl vinyl sulfone or Opplozers camphorsultam chiral dipolarophile leading to the synthesis of two novel tropane compounds.
Keywords: Cocaine antagonists, tropane, 1,3-dipolar cycloaddition, cyclic azomethine ylide, exo/endo-selectivity
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