Abstract
Tri-substituted oxazoles, appearing in several anticancer natural products and various other bioactive compounds, have become increasingly visible in recent years. Research into the synthesis of such oxazoles has led to the development of new synthetic methods as well as refinements of classic methods of their synthesis. In addition, a number of research groups have pursued the synthesis of fully-functionalized-oxazole-containing natural products. We review recent investigations (2004-present) into methods of tri-substituted oxazole synthesis, and the construction of complex natural products containing such oxazoles.
Keywords: Methodology, natural product, tri-substituted oxazole, heterocycles, review, total synthesis, drug discovery, Tri-substituted oxazoles, Nitrogenous heterocycles, myriad, Telomestatin, anticancer activities, Martefragin A, Siphonazole
Related Books
2-Deoxy-D-Glucose: Chemistry and Biology
Chiral Ionic Liquids: Applications in Chemistry and Technology
Basics of Organic Chemistry: A Textbook for Undergraduate Students
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
17