Abstract
The biological importance and activity of fluorinated carbohydrates is a focus of numerous investigations to date. The introduction of fluorine atom(s) can be achieved by a few means such as the classical fluorination, the building block strategy and the radical addition. This is a mini review of carbohydrates containing fluorine atom(s) developed in the past decade. General preparative methods to the fluorinated carbohydrates are organized according to the type of fluorine atom(s) in their molecular structures. The aspects concerning their N-, P-, S- and halogen-containing derivatives and some potential applications in bioorganic chemistry are also discussed.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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