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Anti-Cancer Agents in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1871-5206
ISSN (Online): 1875-5992

Aromatase: The Enzyme and Its Inhibition

Author(s): Lee Banting and Sabbir Ahmed

Volume 9, Issue 6, 2009

Page: [627 - 641] Pages: 15

DOI: 10.2174/187152009788680037

Price: $65

Abstract

The genetic control, mechanism of action and inhibition of aromatase for potential therapeutic benefits in the arena of hormone dependent illness continues to be of considerable interest. The work presented here concentrates on recent advances in the mechanistic aspects of the aromatase enzyme and the nature of the chemical entities that lead to its inhibition.

Keywords: Aromatase, inhibition, enzyme, mechanism, natural products, heterocyclic, inhibitor


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