Login Register Cart 0
Generic placeholder image

The Natural Products Journal

Editor-in-Chief

ISSN (Print): 2210-3155
ISSN (Online): 2210-3163

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Review Article

Herbal Medicinal Nanoformulations for Psoriasis Treatment: Current State of Knowledge and Future Directions

Author(s): Himanshu Sharma, Neha Gupta, Nitika Garg*, Sanchit Dhankhar, Samrat Chauhan, Suresh Beniwal and Deepak Saini

Volume 14, Issue 7, 2024

Published on: 18 January, 2024

Article ID: e180124225808 Pages: 19

DOI: 10.2174/0122103155273976231126141100

Price: $65

Abstract

Background: Psoriasis is a persistent immune system disorder that influences the skin, leading to red, flaky patches that can be painful and irritated.

Objective: Traditional treatments for psoriasis, such as topical creams and oral medications, may be effective but also have potential side effects. Herbal remedies have been used for centuries to treat skin conditions, and advancements in nanotechnology have led to the development of herbal nanoformulations that offer several advantages over traditional herbal remedies, such as efficacy, safety, and targeted delivery.

Methods: The studies and reviews published under the title were looked up in several databases (including PubMed, Elsevier, and Google Scholar).

Results: Several herbal nanoformulations, including those containing curcumin, aloe vera, and neem, have been shown to exhibit anti-inflammatory and immunomodulatory impacts, which will be useful within the treatment of psoriasis. However, more study is required to decide the efficacy and safety of these details, as well as the optimal dosing, duration of treatment, and potential side effects.

Conclusion: Overall, herbal nanoformulations represent a promising area of research for the treatment of psoriasis, and may offer a safe and effective alternative or adjunct therapy to conventional treatments. This review article summarizes the present state of information for the herbal nanoformulations role in the treatment of psoriasis and their future perspectives.

Graphical Abstract

[1]
Orasan, M.S.; Roman, I.I.; Coneac, A. Evaluation of psoriasis patients. In: Tailored Treatments in Psoriatic Patients; IntechOpen, 2018; 79763, pp. 1-2.
[2]
Thornton, A.; Honeywell; Marlon; LeBron; Anya, L.; Henderson; Arlette; Jones, J. Understanding treatment options for psoriasis: Dermatology. J. Mod. Pharm., 2005, 12(7), 14-20.
[3]
Lima, X.T.; Minnillo, R.; Spencer, J.M.; Kimball, A.B. Psoriasis prevalence among the 2009 AAD national melanoma/skin cancer screening program participants. J. Eur. Acad. Dermatol. Venereol., 2013, 27(6), 680-685.
[http://dx.doi.org/10.1111/j.1468-3083.2012.04531.x] [PMID: 22471885]
[4]
Shrivastava, V.K.; Londhe, N.D.; Sonawane, R.S.; Suri, J.S. Computer-aided diagnosis of psoriasis skin images with HOS, texture and color features: A first comparative study of its kind. Comput. Methods Programs Biomed., 2016, 126, 98-109.
[http://dx.doi.org/10.1016/j.cmpb.2015.11.013] [PMID: 26830378]
[5]
Bayaraa, B.; Imafuku, S. Relationship between environmental factors, age of onset and familial history in Japanese patients with psoriasis. J. Dermatol., 2018, 45(6), 715-718.
[http://dx.doi.org/10.1111/1346-8138.14321] [PMID: 29611229]
[6]
de Jong, E.M.G.J. The course of psoriasis. Clin. Dermatol., 1997, 15(5), 687-692.
[http://dx.doi.org/10.1016/S0738-081X(97)00023-0] [PMID: 9313967]
[7]
Mease, P.J.; Gladman, D.D.; Papp, K.A.; Khraishi, M.M.; Thaçi, D.; Behrens, F.; Northington, R.; Fuiman, J.; Bananis, E.; Boggs, R.; Alvarez, D. Prevalence of rheumatologist-diagnosed psoriatic arthritis in patients with psoriasis in European/North American dermatology clinics. J. Am. Acad. Dermatol., 2013, 69(5), 729-735.
[http://dx.doi.org/10.1016/j.jaad.2013.07.023] [PMID: 23981683]
[8]
Singh, S. Psoriasis and suicidality: A systematic review and metaanalysis. J Am Acad Dermatol, 2017, 77(3), 445-440. e2
[http://dx.doi.org/10.1016/j.jaad.2017.05.019]
[9]
Williamson, D. Wild & Well: Dani’s Six commonsense steps to radical healing; Morgan James Publishing, 2021.
[10]
Dhankhar, S.; Chauhan, S.; Mehta, D.K.; Nitika; Saini, K.; Saini, M.; Das, R.; Gupta, S.; Gautam, V. Novel targets for potential therapeutic use in Diabetes mellitus. Diabetol. Metab. Syndr., 2023, 15(1), 17.
[http://dx.doi.org/10.1186/s13098-023-00983-5] [PMID: 36782201]
[11]
Thomas, J.; Parimalam, K. Treating pediatric plaque psoriasis: Challenges and solutions. Pediatric Health Med. Ther., 2016, 7, 25-38.
[http://dx.doi.org/10.2147/PHMT.S75834] [PMID: 29388608]
[12]
Kuchekar, A.B. Psoriasis: A comprehensive review. Int. j. pharm. life sci., 2011, 2(6)
[13]
Betteridge, N.; Boehncke, W.H.; Bundy, C.; Gossec, L.; Gratacós, J.; Augustin, M. Promoting patient‐centred care in psoriatic arthritis: A multidisciplinary E uropean perspective on improving the patient experience. J. Eur. Acad. Dermatol. Venereol., 2016, 30(4), 576-585.
[http://dx.doi.org/10.1111/jdv.13306] [PMID: 26377041]
[14]
Fereig, S.A.; El-Zaafarany, G.M.; Arafa, M.G.; Abdel-Mottaleb, M.M.A. Tackling the various classes of nano-therapeutics employed in topical therapy of psoriasis. Drug Deliv., 2020, 27(1), 662-680.
[http://dx.doi.org/10.1080/10717544.2020.1754527] [PMID: 32393082]
[15]
Pradhan, M.; Alexander, A.; Singh, M.R.; Singh, D.; Saraf, S.; Saraf, S.; Ajazuddin, Understanding the prospective of nano-formulations towards the treatment of psoriasis. Biomed. Pharmacother., 2018, 107, 447-463.
[http://dx.doi.org/10.1016/j.biopha.2018.07.156] [PMID: 30103117]
[16]
Thatikonda, S.; Pooladanda, V.; Sigalapalli, D.K.; Godugu, C. Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation. Cell Death Dis., 2020, 11(1), 21.
[http://dx.doi.org/10.1038/s41419-019-2212-y] [PMID: 31924750]
[17]
Saharan, R. Hydrogel-based drug delivery system in diabetes management. Pharm. Nanotechnol., 2023, 12, 1-11.
[http://dx.doi.org/10.15835/nbha4219484]
[18]
Boca, A.N.; Tataru, A.; Buzoianu, A.D.; Pincelli, C.; Socaciu, C. Pharmacological benefits of herbal formulations in the management of psoriasis vulgaris. Not. Bot. Horti Agrobot. Cluj-Napoca, 2014, 42(1), 1-8.
[http://dx.doi.org/10.15835/nbha4219484]
[19]
Shree, D.; Patra, C.N.; Sahoo, B.M. Novel herbal nanocarriers for treatment of dermatological disorders. Pharm. Nanotechnol., 2022, 10(4), 246-256.
[http://dx.doi.org/10.2174/2211738510666220622123019] [PMID: 35733305]
[20]
Raychaudhuri, S.K.; Maverakis, E.; Raychaudhuri, S.P. Diagnosis and classification of psoriasis. Autoimmun. Rev., 2014, 13(4-5), 490-495.
[http://dx.doi.org/10.1016/j.autrev.2014.01.008] [PMID: 24434359]
[21]
Zeng, J.; Luo, S.; Huang, Y.; Lu, Q. Critical role of environmental factors in the pathogenesis of psoriasis. J. Dermatol., 2017, 44(8), 863-872.
[http://dx.doi.org/10.1111/1346-8138.13806] [PMID: 28349593]
[22]
Henseler, T. Genetics of psoriasis. Arch. Dermatol. Res., 1998, 290(9), 463-476.
[http://dx.doi.org/10.1007/s004030050338] [PMID: 9808339]
[23]
Legein, B.; Temmerman, L.; Biessen, E.A.L.; Lutgens, E. Inflammation and immune system interactions in atherosclerosis. Cell. Mol. Life Sci., 2013, 70(20), 3847-3869.
[http://dx.doi.org/10.1007/s00018-013-1289-1] [PMID: 23430000]
[24]
Pandya, N.M.; Dhalla, N.S.; Santani, D.D. Angiogenesis—a new target for future therapy. Vascul. Pharmacol., 2006, 44(5), 265-274.
[http://dx.doi.org/10.1016/j.vph.2006.01.005] [PMID: 16545987]
[25]
Barani, M.; Sangiovanni, E.; Angarano, M.; Rajizadeh, M.A.; Mehrabani, M.; Piazza, S.; Gangadharappa, H.V.; Pardakhty, A.; Mehrbani, M.; Dell’Agli, M.; Nematollahi, M.H. Phytosomes as innovative delivery systems for phytochemicals: A comprehensive review of literature. Int. J. Nanomedicine, 2021, 16, 6983-7022.
[http://dx.doi.org/10.2147/IJN.S318416] [PMID: 34703224]
[26]
Saleem, S.; Iqubal, M.K.; Garg, S.; Ali, J.; Baboota, S. Trends in nanotechnology-based delivery systems for dermal targeting of drugs: an enticing approach to offset psoriasis. Expert Opin. Drug Deliv., 2020, 17(6), 817-838.
[http://dx.doi.org/10.1080/17425247.2020.1758665] [PMID: 32315216]
[27]
Khogta, S.; Patel, J.; Barve, K.; Londhe, V. Herbal nano-formulations for topical delivery. J. Herb. Med., 2020, 20, 100300.
[http://dx.doi.org/10.1016/j.hermed.2019.100300]
[28]
Chauhan, S. Current approaches in healing of wounds in diabetes and diabetic foot ulcers. Curr. Bioact. Compd., 2023, 19(3), 104-121.
[29]
Bakshi, H.; Nagpal, M.; Singh, M.; Dhingra, G.A.; Aggarwal, G. Treatment of psoriasis: A comprehensive review of entire therapies. Curr. Drug Saf., 2020, 15(2), 82-104.
[http://dx.doi.org/10.2174/22123911MTAziOTU84] [PMID: 31994468]
[30]
Dua, J.; Rana, A.; Bhandari, A. Liposome: Methods of preparation and applications. Int J Pharm Stud Res, 2012, 3(2), 14-20.
[31]
Campos, J. Solid lipid nanoparticles (SLN): Prediction of toxicity, metabolism, fate and physicochemical properties; Nanopharmaceuticals, 2020, pp. 1-15.
[http://dx.doi.org/10.1016/B978-0-12-817778-5.00001-4]
[32]
Grottkau, B.; Cai, X.; Wang, J.; Yang, X.; Lin, Y. Polymeric nanoparticles for a drug delivery system. Curr. Drug Metab., 2013, 14(8), 840-846.
[http://dx.doi.org/10.2174/138920021131400105] [PMID: 24016112]
[33]
Rai, A.K. Dendrimers: A potential carrier for targeted drug delivery system. Pharmaceutical and Biological Evaluations, 2016, 3(3), 275-287.
[34]
Singh, Y.; Meher, J.G.; Raval, K.; Khan, F.A.; Chaurasia, M.; Jain, N.K.; Chourasia, M.K. Nanoemulsion: Concepts, development and applications in drug delivery. J. Control. Release, 2017, 252, 28-49.
[http://dx.doi.org/10.1016/j.jconrel.2017.03.008] [PMID: 28279798]
[35]
Kraft, J.C.; Freeling, J.P.; Wang, Z.; Ho, R.J.Y. Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems. J. Pharm. Sci., 2014, 103(1), 29-52.
[http://dx.doi.org/10.1002/jps.23773] [PMID: 24338748]
[36]
Rahman, M.; Akhter, S.; Ahmad, J.; Ahmad, M.Z.; Beg, S.; Ahmad, F.J. Nanomedicine-based drug targeting for psoriasis: potentials and emerging trends in nanoscale pharmacotherapy. Expert Opin. Drug Deliv., 2015, 12(4), 635-652.
[http://dx.doi.org/10.1517/17425247.2015.982088] [PMID: 25439967]
[37]
He, Y.; Yue, Y.; Zheng, X.; Zhang, K.; Chen, S.; Du, Z. Curcumin, inflammation, and chronic diseases: How are they linked? Molecules, 2015, 20(5), 9183-9213.
[http://dx.doi.org/10.3390/molecules20059183] [PMID: 26007179]
[38]
Lalit, K. Phyto-pharmacological review of Coccinia indica. World J. Pharm. Pharm. Sci., 2014, 3(2), 1734-1745. [WJPPS].
[39]
Kaur, N. Anti-inflammatory and analgesic activity of curcumin with different NSAIDS. Indian Drugs, 2018, 55(7)
[40]
Dhankar, S. Artificial intelligence in the management of neurodegenerative disorders. CNS Neurol. Disord. Drug Targets, 2023, 23, 1-10.
[http://dx.doi.org/10.1007/s11481-013-9462-8] [PMID: 23645137]
[41]
Gibney, S.M.; Drexhage, H.A. Evidence for a dysregulated immune system in the etiology of psychiatric disorders. J. Neuroimmune Pharmacol., 2013, 8(4), 900-920.
[http://dx.doi.org/10.1007/s11481-013-9462-8] [PMID: 23645137]
[42]
Maheshwari, R. Natural ingredients/botanical extracts for the nutraceutical industry In: Flavors for Nutraceutical and Functional Foods; CRC Press, 2018; pp. 75-122.
[43]
Briganti, S.; Picardo, M. Antioxidant activity, lipid peroxidation and skin diseases. What’s new. J. Eur. Acad. Dermatol. Venereol., 2003, 17(6), 663-669.
[http://dx.doi.org/10.1046/j.1468-3083.2003.00751.x] [PMID: 14761133]
[44]
Ahmed, M.S.; Khan, I.J.; Aman, S.; Chauhan, S.; Kaur, N.; Shriwastav, S.; Goel, K.; Saini, M.; Dhankar, S.; Singh, T.G.; Dev, J.; Mujwar, S. Phytochemical investigations, in-vitro antioxidant, antimicrobial potential, and in-silico computational docking analysis of Euphorbia milii Des Moul. J. Exp. Biol. Agric. Sci., 2023, 11(2), 380-393.
[http://dx.doi.org/10.18006/2023.11(2).380.393]
[45]
Ganesan, P.; Choi, D.K. Current application of phytocompound-based nanocosmeceuticals for beauty and skin therapy. Int. J. Nanomedicine, 2016, 11, 1987-2007.
[http://dx.doi.org/10.2147/IJN.S104701] [PMID: 27274231]
[46]
Chauhan, S. Antihyperglycemic and antioxidant potential of plant extract of litchi chinensis and glycine max. Int. J. Nutr. Pharmacol. Neurol. Dis., 2021, 11(3), 225-233.
[47]
Razavi, B.M.; Ghasemzadeh Rahbardar, M.; Hosseinzadeh, H. A review of therapeutic potentials of turmeric (CURCUMA LONGA) and its active constituent, curcumin, on inflammatory disorders, pain, and their related patents. Phytother. Res., 2021, 35(12), 6489-6513.
[http://dx.doi.org/10.1002/ptr.7224] [PMID: 34312922]
[48]
Mao, K.L.; Fan, Z.L.; Yuan, J.D.; Chen, P.P.; Yang, J.J.; Xu, J.; ZhuGe, D.L.; Jin, B.H.; Zhu, Q.Y.; Shen, B.X.; Sohawon, Y.; Zhao, Y.Z.; Xu, H.L. Skin-penetrating polymeric nanoparticles incorporated in silk fibroin hydrogel for topical delivery of curcumin to improve its therapeutic effect on psoriasis mouse model. Colloids Surf. B Biointerfaces, 2017, 160, 704-714.
[http://dx.doi.org/10.1016/j.colsurfb.2017.10.029] [PMID: 29035818]
[49]
Wermeling, D.P.; Banks, S.L.; Hudson, D.A.; Gill, H.S.; Gupta, J.; Prausnitz, M.R.; Stinchcomb, A.L. Microneedles permit transdermal delivery of a skin-impermeant medication to humans. Proc. Natl. Acad. Sci. USA, 2008, 105(6), 2058-2063.
[http://dx.doi.org/10.1073/pnas.0710355105] [PMID: 18250310]
[50]
Kumar, S.; Singh, K.K.; Rao, R. Enhanced anti-psoriatic efficacy and regulation of oxidative stress of a novel topical babchi oil (Psoralea corylifolia) cyclodextrin-based nanogel in a mouse tail model. J. Microencapsul., 2019, 36(2), 140-155.
[http://dx.doi.org/10.1080/02652048.2019.1612475] [PMID: 31030587]
[51]
Agrawal, U.; Gupta, M.; Vyas, S.P. Capsaicin delivery into the skin with lipidic nanoparticles for the treatment of psoriasis. Artif. Cells Nanomed. Biotechnol., 2015, 43(1), 33-39.
[http://dx.doi.org/10.3109/21691401.2013.832683] [PMID: 24040836]
[52]
Gupta, R.; Gupta, M.; Mangal, S.; Agrawal, U.; Vyas, S.P. Capsaicin-loaded vesicular systems designed for enhancing localized delivery for psoriasis therapy. Artif. Cells Nanomed. Biotechnol., 2016, 44(3), 825-834.
[PMID: 25465045]
[53]
Khan, A.; Qadir, A.; Ali, F.; Aqil, M. Phytoconstituents based nanomedicines for the management of psoriasis. J. Drug Deliv. Sci. Technol., 2021, 64, 102663.
[http://dx.doi.org/10.1016/j.jddst.2021.102663]
[54]
Qadir, A.; Aqil, M.; Ali, A.; Warsi, M.H.; Mujeeb, M.; Ahmad, F.J.; Ahmad, S.; Beg, S. Nanostructured lipidic carriers for dual drug delivery in the management of psoriasis: Systematic optimization, dermatokinetic and preclinical evaluation. J. Drug Deliv. Sci. Technol., 2020, 57, 101775.
[http://dx.doi.org/10.1016/j.jddst.2020.101775]
[55]
Zhang, Y.; Xia, Q.; Li, Y.; He, Z.; Li, Z.; Guo, T.; Wu, Z.; Feng, N. CD44 assists the topical anti-psoriatic efficacy of curcumin-loaded hyaluronan-modified ethosomes: A new strategy for clustering drug in inflammatory skin. Theranostics, 2019, 9(1), 48-64.
[http://dx.doi.org/10.7150/thno.29715] [PMID: 30662553]
[56]
Iriventi, P.; Gupta, N.V.; Osmani, R.A.M.; Balamuralidhara, V. Design & development of nanosponge loaded topical gel of curcumin and caffeine mixture for augmented treatment of psoriasis. Daru, 2020, 28(2), 489-506.
[http://dx.doi.org/10.1007/s40199-020-00352-x] [PMID: 32472531]
[57]
Ajitomi, A.; Inoue, Y.; Horita, M.; Nakaho, K. Bacterial wilt of three Curcuma species, C. longa (turmeric), C. aromatica (wild turmeric) and C. zedoaria (zedoary) caused by Ralstonia solanacearum in Japan. J. Gen. Plant Pathol., 2015, 81(4), 315-319.
[http://dx.doi.org/10.1007/s10327-015-0596-9]
[58]
Reena, K.M.; Singh, L.; Sharma, S. Curcumin: A review of its’ efficacy in the management of psoriasis. Drug Deliv. Lett., 2022, 12(3), 163-183.
[http://dx.doi.org/10.2174/2210303112666220428101738]
[59]
Mwale, M. Use of herbal plants in poultry health management in the Mushagashe small-scale commercial farming area in Zimbabwe. Int. J. Appl. Res. Vet. Med., 2005, 3(2), 163-170.
[60]
Hernández-Pérez, T.; Gómez-García, M.R.; Valverde, M.E.; Paredes-López, O. Capsicum annuum (hot pepper): An ancient Latin‐American crop with outstanding bioactive compounds and nutraceutical potential. A review. Compr. Rev. Food Sci. Food Saf., 2020, 19(6), 2972-2993.
[http://dx.doi.org/10.1111/1541-4337.12634] [PMID: 33337034]
[61]
Zhang, Y.; Zhang, H.; Jiang, B.; Yan, S.; Lu, J. A promising therapeutic target for psoriasis: Neuropeptides in human skin. Int. Immunopharmacol., 2020, 87, 106755.
[http://dx.doi.org/10.1016/j.intimp.2020.106755] [PMID: 32736190]
[62]
Jungbauer, A.; Medjakovic, S. Anti-inflammatory properties of culinary herbs and spices that ameliorate the effects of metabolic syndrome. Maturitas, 2012, 71(3), 227-239.
[http://dx.doi.org/10.1016/j.maturitas.2011.12.009] [PMID: 22226987]
[63]
Mittal, P.; Dhankhar, S.; Chauhan, S.; Garg, N.; Bhattacharya, T.; Ali, M.; Chaudhary, A.A.; Rudayni, H.A.; Al-Zharani, M.; Ahmad, W.; Khan, S.U.D.; Singh, T.G.; Mujwar, S. A review on natural antioxidants for their role in the treatment of parkinson’s disease. Pharmaceuticals, 2023, 16(7), 908.
[http://dx.doi.org/10.3390/ph16070908] [PMID: 37513820]
[64]
Pandey, A.; Singh, S. Aloe vera: A systematic review of its industrial and ethno-medicinal efficacy. Int. J. Pharm. Res. Allied Sci, 2016, 5(1)
[65]
Radha, M.H.; Laxmipriya, N.P. Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. J. Tradit. Complement. Med., 2015, 5(1), 21-26.
[http://dx.doi.org/10.1016/j.jtcme.2014.10.006] [PMID: 26151005]
[66]
Manvitha, K.; Bidya, B. Aloe vera: A wonder plant its history, cultivation and medicinal uses. J. Pharmacogn. Phytochem., 2014, 2(5), 85-88.
[67]
Samrat Chauhan, L.K.; Samrat Kaur, Navpreet.; Singh, Randhir Potential anti-arthritic agents from indian medicinal plants. Res. Rev. J. Pharm. Pharm. Sci., 2015, 4(3), 10-22.
[68]
Garg, T.; Rath, G.; Goyal, A. Ancient and advanced approaches for the treatment of an inflammatory autoimmune disease− psoriasis. Crit. Rev. Ther. Drug Carrier Syst., 2014, 31(4)
[69]
Akhdar, M.; Abedini, R.; Tavakolpour, S.; Gholibeigian, Z.; Azizpour, A. A randomized, double-blind, placebo-controlled trial of a commercial Aloe vera gel for mitigation of phototherapy side-effects in vitiligo patients. J. Herb. Med., 2021, 28, 100442.
[http://dx.doi.org/10.1016/j.hermed.2021.100442]
[70]
Flora, K.; Hahn, M.; Rosen, H.; Benner, K. Milk thistle (Silybum marianum) for the therapy of liver disease. Am. J. Gastroenterol., 1998, 93(2), 139-143.
[http://dx.doi.org/10.1111/j.1572-0241.1998.00139.x] [PMID: 9468229]
[71]
Saeed, M.; Babazadeh, D.; Arif, M.; Arain, M.A.; Bhutto, Z.A.; Shar, A.H.; Kakar, M.U.; Manzoor, R.; Chao, S. Silymarin: A potent hepatoprotective agent in poultry industry. Worlds Poult. Sci. J., 2017, 73(3), 483-492.
[http://dx.doi.org/10.1017/S0043933917000538]
[72]
Kumar, C.S. Psychological Concerns in Ethnic Skin. Essentials for aesthetic dermatology in ethnic Skin: Practice and procedure, 2023.
[http://dx.doi.org/10.1201/9780429243769-16]
[73]
Basra, M.K.A.; Fenech, R.; Gatt, R.M.; Salek, M.S.; Finlay, A.Y. The dermatology life quality index 1994-2007: A comprehensive review of validation data and clinical results. Br. J. Dermatol., 2008, 159(5), 997-1035.
[http://dx.doi.org/10.1111/j.1365-2133.2008.08832.x] [PMID: 18795920]
[74]
Raut, G.; Wairkar, S. Management of psoriasis with nutraceuticals: An update. Complement. Ther. Clin. Pract., 2018, 31, 25-30.
[http://dx.doi.org/10.1016/j.ctcp.2018.01.007] [PMID: 29705464]
[75]
Chen, X.P.; Li, W.; Xiao, X.F.; Zhang, L.L.; Liu, C.X. Phytochemical and pharmacological studies on radix angelica sinensis. Chin. J. Nat. Med., 2013, 11(6), 577-587.
[http://dx.doi.org/10.1016/S1875-5364(13)60067-9] [PMID: 24345498]
[76]
Kumar, D.; Rajguru, J.P.; Maya, D.; Suri, P.; Bhardwaj, S.; Patel, N. Update on psoriasis: A review. J. Family Med. Prim. Care, 2020, 9(1), 20-24.
[http://dx.doi.org/10.4103/jfmpc.jfmpc_689_19] [PMID: 32110559]
[77]
Ashwood-Smith, M.J.; Poulton, G.A.; Barker, M.; Mildenberger, M. 5-Methoxypsoralen, an ingredient in several suntan preparations, has lethal, mutagenic and clastogenic properties. Nature, 1980, 285(5764), 407-409.
[http://dx.doi.org/10.1038/285407a0] [PMID: 6991953]
[78]
Weichenthal, M.; Schwarz, T. Phototherapy: How does UV work? Photodermatol. Photoimmunol. Photomed., 2005, 21(5), 260-266.
[http://dx.doi.org/10.1111/j.1600-0781.2005.00173.x] [PMID: 16149939]
[79]
Albahri, G.; Badran, A.; Hijazi, A.; Daou, A.; Baydoun, E.; Nasser, M.; Merah, O. The therapeutic wound healing bioactivities of various medicinal plants. Life, 2023, 13(2), 317.
[http://dx.doi.org/10.3390/life13020317] [PMID: 36836674]
[80]
Dabholkar, N.; Rapalli, V.K.; Singhvi, G. Potential herbal constituents for psoriasis treatment as protective and effective therapy. Phytother. Res., 2021, 35(5), 2429-2444.
[http://dx.doi.org/10.1002/ptr.6973] [PMID: 33277958]
[81]
Mease, P.J. Measures of psoriatic arthritis: Tender and Swollen Joint Assessment, Psoriasis Area and Severity Index (PASI), Nail Psoriasis Severity Index (NAPSI), Modified Nail Psoriasis Severity Index (mNAPSI), Mander/Newcastle Enthesitis Index (MEI), Leeds Enthesitis Index (LEI), Spondyloarthritis Research Consortium of Canada (SPARCC), Maastricht Ankylosing Spondylitis Enthesis Score (MASES), Leeds Dactylitis Index (LDI), Patient Global for Psoriatic Arthritis, Dermatology Life Quality Index (DLQI), Psoriatic Arthritis Quality of Life (PsAQOL), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), Psoriatic Arthritis Response Criteria (PsARC), Psoriatic Arthritis Joint Activity Index (PsAJAI), Disease Activity in Psoriatic Arthritis (DAPSA), and Composite Psoriatic Disease Activity Index (CPDAI). Arthritis Care Res., 2011, 63(S11)(Suppl. 11), S64-S85.
[PMID: 22588772]
[82]
M.N. and S. Lueangarun, Efficacy of ointment containing anti-inflammatory effect in the treatment of chronic hand eczema: a split-hand, evaluator-blinded, randomized, controlled trial; Thammasat University, 2019.
[83]
Jarouliya, U.; Keservani, R.K. Nutraceutical components in the treatment of psoriasis and psoriatic arthritis In: Psoriasis and Psoriatic Arthritis; CRC Press, 2017; pp. 283-298.
[http://dx.doi.org/10.1201/9781315152912-18]
[84]
Suroowan, S.; Mahomoodally, F. Herbal products for common auto-inflammatory disorders-novel approaches. Comb. Chem. High Throughput Screen., 2018, 21(3), 161-174.
[http://dx.doi.org/10.2174/1386207321666180213093449] [PMID: 29436996]
[85]
Ali, B.; Al-Wabel, N.A.; Shams, S.; Ahamad, A.; Khan, S.A.; Anwar, F. Essential oils used in aromatherapy: A systemic review. Asian Pac. J. Trop. Biomed., 2015, 5(8), 601-611.
[http://dx.doi.org/10.1016/j.apjtb.2015.05.007]
[86]
Ashraf, M.; El-Sawy, H.S.; El Zaafarany, G.M.; Abdel-Mottaleb, M.M.A. Can essential oils/botanical agents smart-nanoformulations be the winning cards against psoriasis? Pharmaceutics, 2023, 15(3), 750.
[http://dx.doi.org/10.3390/pharmaceutics15030750] [PMID: 36986611]
[87]
Felgueiras, H.P. An insight into biomolecules for the treatment of skin infectious diseases. Pharmaceutics, 2021, 13(7), 1012.
[http://dx.doi.org/10.3390/pharmaceutics13071012] [PMID: 34371704]
[88]
Sarafian, G.; Afshar, M.; Mansouri, P.; Asgarpanah, J.; Raoufinejad, K.; Rajabi, M. Topical turmeric microemulgel in the management of plaque psoriasis; a clinical evaluation. Iran. J. Pharm. Res., 2015, 14(3), 865-876.
[PMID: 26330875]
[89]
Files, B.T.P. Common Name: Wintergreen| Scientific Name: Gaultheria Procumbens.
[90]
Vergnes, S.; Ladouce, N.; Fournier, S.; Ferhout, H.; Attia, F.; Dumas, B. Foliar treatments with Gaultheria procumbens essential oil induce defense responses and resistance against a fungal pathogen in Arabidopsis. Front. Plant Sci., 2014, 5, 477.
[http://dx.doi.org/10.3389/fpls.2014.00477] [PMID: 25295045]
[91]
Michel, P.; Granica, S.; Rosińska, K.; Rojek, J.; Poraj, Ł.; Olszewska, M.A. Biological and chemical insight into Gaultheria procumbens fruits: A rich source of anti-inflammatory and antioxidant salicylate glycosides and procyanidins for food and functional application. Food Funct., 2020, 11(9), 7532-7544.
[http://dx.doi.org/10.1039/D0FO01750G] [PMID: 32812975]
[92]
Shikiar, R.; Willian, M.K.; Okun, M.M.; Thompson, C.S.; Revicki, D.A. The validity and responsiveness of three quality of life measures in the assessment of psoriasis patients: Results of a phase II study. Health Qual. Life Outcomes, 2006, 4(1), 71.
[http://dx.doi.org/10.1186/1477-7525-4-71] [PMID: 17005043]
[93]
Beveridge, R. Slippery Elm.,
[94]
Daniyal, M.; Akram, M.; Zainab, R.; Munir, N.; Shah, S.M.A.; Liu, B.; Wang, W.; Riaz, M.; Jabeen, F. Progress and prospects in the management of psoriasis and developments in phyto‐therapeutic modalities. Dermatol. Ther., 2019, 32(3), e12866.
[http://dx.doi.org/10.1111/dth.12866] [PMID: 30838736]
[95]
Cheung, S.; Lim, K.T.; Tai, J. Antioxidant and anti-inflammatory properties of ESSIAC and Flor-essence. Oncol. Rep., 2005, 14(5), 1345-1350.
[http://dx.doi.org/10.3892/or.14.5.1345] [PMID: 16211307]
[96]
Herbals in the holistic treatment of psoriasis. J Clin Dermatol, 2015, 16, 147-165.
[97]
Bark, C. AmericanHerbal Pharmacopoeia., 1999.
[98]
Edwards, S.E. Phytopharmacy: An evidence-based guide to herbal medicinal products; John Wiley & Sons, 2015.
[http://dx.doi.org/10.1002/9781118543436]
[99]
Kebede, B.H.; Forsido, S.F.; Tola, Y.B.; Astatkie, T. Free radical scavenging capacity, antibacterial activity and essential oil composition of turmeric (Curcuma domestica) varieties grown in Ethiopia. Heliyon, 2021, 7(2), e06239.
[http://dx.doi.org/10.1016/j.heliyon.2021.e06239] [PMID: 33659752]
[100]
Zhang, X.; Chen, Q.; Wang, Y.; Peng, W.; Cai, H. Effects of curcumin on ion channels and transporters. Front. Physiol., 2014, 5, 94.
[http://dx.doi.org/10.3389/fphys.2014.00094] [PMID: 24653706]
[101]
Gupta, S.C.; Patchva, S.; Aggarwal, B.B. Therapeutic roles of curcumin: Lessons learned from clinical trials. AAPS J., 2013, 15(1), 195-218.
[http://dx.doi.org/10.1208/s12248-012-9432-8] [PMID: 23143785]
[102]
Abebe, W. Review of herbal medications with the potential to cause bleeding: dental implications, and risk prediction and prevention avenues. EPMA J., 2019, 10(1), 51-64.
[http://dx.doi.org/10.1007/s13167-018-0158-2] [PMID: 30984314]
[103]
Coats, V.C.; Stack, P.A.; Rumpho, M.E. Japanese barberry seed predation by Rhagoletis meigenii fruit flies harboring Wolbachia endosymbionts. Symbiosis, 2013, 59(3), 145-156.
[http://dx.doi.org/10.1007/s13199-013-0223-5]
[104]
Toiu, A.; Mocan, A.; Vlase, L.; Pârvu, A.E.; Vodnar, D.C.; Gheldiu, A.M.; Moldovan, C.; Oniga, I. Comparative phytochemical profile, antioxidant, antimicrobial and in vivo anti-inflammatory activity of different extracts of traditionally used Romanian Ajuga genevensis L. and A. reptans L.(Lamiaceae). Molecules, 2019, 24(8), 1597.
[http://dx.doi.org/10.3390/molecules24081597] [PMID: 31018502]
[105]
Herman, A.; Herman, A. Topically used herbal products for the treatment of psoriasis–mechanism of action, drug delivery, clinical studies. Planta Med., 2016, 82(17), 1447-1455.
[http://dx.doi.org/10.1055/s-0042-115177] [PMID: 27574899]
[106]
Reuter, J.; Wölfle, U.; Weckesser, S.; Schempp, C. Which plant for which skin disease? Part 1: Atopic dermatitis, psoriasis, acne, condyloma and herpes simplex. J. Dtsch. Dermatol. Ges., 2010, 8(10), 788-796.
[http://dx.doi.org/10.1111/j.1610-0387.2010.07496.x] [PMID: 20707875]
[107]
Tushar; Basak, S.; Sarma, G.C.; Rangan, L. Ethnomedical uses of Zingiberaceous plants of Northeast India. J. Ethnopharmacol., 2010, 132(1), 286-296.
[http://dx.doi.org/10.1016/j.jep.2010.08.032] [PMID: 20727402]
[108]
Ramanunny, A.K.; Wadhwa, S.; Kumar Singh, S.; Kumar, B.; Gulati, M.; Kumar, A.; Almawash, S.; Al Saqr, A.; Gowthamarajan, K.; Dua, K.; Singh, H.; Vishwas, S.; Khursheed, R.; Rahana Parveen, S.; Venkatesan, A.; Paudel, K.R.; Hansbro, P.M.; Kumar Chellappan, D. Topical non-aqueous nanoemulsion of Alpinia galanga extract for effective treatment in psoriasis: In vitro and in vivo evaluation. Int. J. Pharm., 2022, 624, 121882.
[http://dx.doi.org/10.1016/j.ijpharm.2022.121882] [PMID: 35671853]
[109]
Saelee, C.; Thongrakard, V.; Tencomnao, T. Effects of Thai medicinal herb extracts with anti-psoriatic activity on the expression on NF-κB signaling biomarkers in HaCaT keratinocytes. Molecules, 2011, 16(5), 3908-3932.
[http://dx.doi.org/10.3390/molecules16053908] [PMID: 21555979]
[110]
Aleem, D.; Tohid, H. Pro-inflammatory cytokines, biomarkers, genetics and the immune system: A mechanistic approach of depression and psoriasis. Revista Colombiana de Psiquiatría (English ed.), 2018, 47(3), 177-186.
[http://dx.doi.org/10.1016/j.rcpeng.2018.05.002] [PMID: 30017041]
[111]
Seo, J.W.; Cho, S.C.; Park, S.J.; Lee, E.J.; Lee, J.H.; Han, S.S.; Pyo, B.S.; Park, D.H.; Kim, B.H. 1′-Acetoxychavicol acetate isolated from Alpinia galanga ameliorates ovalbumin-induced asthma in mice. PLoS One, 2013, 8(2), e56447.
[http://dx.doi.org/10.1371/journal.pone.0056447] [PMID: 23451048]
[112]
Song, H.K.; Park, S.H.; Kim, H.J.; Jang, S.; Kim, T. Alpinia officinarum water extract inhibits the atopic dermatitis-like responses in NC/Nga mice by regulation of inflammatory chemokine production. Biomed. Pharmacother., 2021, 144, 112322.
[http://dx.doi.org/10.1016/j.biopha.2021.112322] [PMID: 34656059]
[113]
Ríos, J.L.; Schinella, G.R.; Andújar, I. Antipsoriatic medicinal plants: from traditional use to clinic In: Ethnobotany; CRC Press, 2019; pp. 158-186.
[114]
Vishwakarma, A.; Arora, P.; Dhobi, M. Thespesia populnea: An ethnomedicinal, phytochemical and pharmacological review. Nat. Prod. J., 2022, 12(2), 2-12.
[http://dx.doi.org/10.2174/2210315510999201210142313]
[115]
Patil, M.S.S.; Nitave, S.A. A review on phytochemical and pharmacological properties of thespesia populnea linn 2021.
[116]
Niculet, E.; Radaschin, D.; Nastase, F.; Draganescu, M.; Baroiu, L.; Miulescu, M.; Arbune, M.; Tatu, A. Influence of phytochemicals in induced psoriasis (Review). Exp. Ther. Med., 2020, 20(4), 3421-3424.
[http://dx.doi.org/ 10.3892/etm.2020.9013] [PMID: 32905089]
[117]
Tiwari, R.; Latheef, S.K.; Ahmed, I.; Iqbal, H.M.N.; Bule, M.H.; Dhama, K.; Samad, H.A.; Karthik, K.; Alagawany, M.; El-Hack, M.E.A.; Yatoo, M.I.; Farag, M.R. Herbal immunomodulators-a remedial panacea for designing and developing effective drugs and medicines: current scenario and future prospects. Curr. Drug Metab., 2018, 19(3), 264-301.
[http://dx.doi.org/10.2174/1389200219666180129125436] [PMID: 29380694]
[118]
Padhye, S. From here to eternity-the secret of Pharaohs: Therapeutic potential of black cumin seeds and beyond. Cancer therapy, 2008, 6(b), 495.
[119]
Gholamnezhad, Z.; Havakhah, S.; Boskabady, M.H. Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review. J. Ethnopharmacol., 2016, 190, 372-386.
[http://dx.doi.org/10.1016/j.jep.2016.06.061] [PMID: 27364039]
[120]
Akbar, S.; Akbar, S. Wrightia tinctoria R. Br.(Apocynaceae) (Syns.: W. laciniata A. DC; W. timorensis Miq.) In: Handbook of 200 Medicinal Plants: A Comprehensive Review of Their Traditional Medical Uses and Scientific Justifications; , 2020; pp. 1951-1956.
[121]
Kale, N. Phyto-pharmacological profile of wrightia tinctoria. 2021.
[http://dx.doi.org/10.52711/2231-5659.2021.00047]
[122]
Kumari, K.M.U.; Yadav, N.P.; Luqman, S. Promising essential oils/plant extracts in the prevention and treatment of dandruff pathogenesis. Curr. Top. Med. Chem., 2022, 22(13), 1104-1133.
[http://dx.doi.org/10.2174/1568026622666220531120226] [PMID: 35642120]
[123]
Bhowmik, D. Herbal remedies of Azadirachta indica and its medicinal application. J. Chem. Pharm. Res., 2010, 2(1), 62-72.
[124]
Devi, S.L.; Divakar, M.C. Wrightia tinctoria (Roxb) R. Br.-An updated Review.
[125]
Palaniswamy, D.; Nithyanantham, M.; Raghu, P.S.; Dwarampudi, L.P. Antipsoriatic activity and cytotoxicity of ethanolic extract of Nigella sativa seeds. Pharmacogn. Mag., 2012, 8(32), 268-272.
[http://dx.doi.org/10.4103/0973-1296.103650] [PMID: 24082629]
[126]
Verma, A. Rubia cordifolia-a review on pharmaconosy and phytochemistry. Int. J. Pharm. Sci. Res., 2016, 7(7), 2720.
[127]
Shrivastav, S. Anti-psoriatic and phytochemical evaluation of Thespesia populnea bark extracts. Int. J. Pharm. Pharm. Sci., 2009, 1(1)
[128]
Srivastava, R. A review on phytochemical, pharmacological, and pharmacognostical profile of Wrightia tinctoria: Adulterant of kurchi. Pharmacogn. Rev., 2014, 8(15), 36-44.
[http://dx.doi.org/10.4103/0973-7847.125528] [PMID: 24600194]
[129]
Miroddi, M.; Navarra, M.; Calapai, F.; Mancari, F.; Giofrè, S.V.; Gangemi, S.; Calapai, G. Review of clinical pharmacology of Aloe vera L. in the treatment of psoriasis. Phytother. Res., 2015, 29(5), 648-655.
[http://dx.doi.org/10.1002/ptr.5316] [PMID: 25756474]
[130]
Grundmann, O. Aloe vera gel research review. Nat. Med. J, 2012, 4(9)
[131]
Nakajima, K.; Sano, S. Mouse models of psoriasis and their relevance. J. Dermatol., 2018, 45(3), 252-263.
[http://dx.doi.org/10.1111/1346-8138.14112] [PMID: 29226571]
[132]
Barnes, J.; Anderson, L.A.; Phillipson, J.D. St John’s wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties. J. Pharm. Pharmacol., 2010, 53(5), 583-600.
[http://dx.doi.org/10.1211/0022357011775910] [PMID: 11370698]
[133]
Sukare, P.; Bhattacharya, R. Herbal plant used in treatment of psoriasis-a systematic review. Research Journal of Pharmacognosy and Phytochemistry, 2020, 12(1), 57-62.
[http://dx.doi.org/10.5958/0975-4385.2020.00011.4]
[134]
Bernstein, S.; Donsky, H.; Gulliver, W.; Hamilton, D.; Nobel, S.; Norman, R. Treatment of mild to moderate psoriasis with Reliéva, a Mahonia aquifolium extract--a double-blind, placebo-controlled study. Am. J. Ther., 2006, 13(2), 121-126.
[http://dx.doi.org/10.1097/00045391-200603000-00007] [PMID: 16645428]
[135]
Herman, A.; Herman, A.P. Herbal products for the treatment of psoriasis. In: Psoriasis and Psoriatic Arthritis; CRC Press., 2017; pp. 299-322.
[http://dx.doi.org/10.1201/9781315152912-19]
[136]
Kocaadam, B.; Şanlier, N. Curcumin, an active component of turmeric ( Curcuma longa ), and its effects on health. Crit. Rev. Food Sci. Nutr., 2017, 57(13), 2889-2895.
[http://dx.doi.org/10.1080/10408398.2015.1077195] [PMID: 26528921]
[137]
Hong, J.; Mosca, M.; Hadeler, E.; Hakimi, M.; Bhutani, T.; Liao, W. The future of personalized medicine in psoriasis. Dermatol. Rev., 2021, 2(5), 282-288.
[http://dx.doi.org/10.1002/der2.87]
[138]
Chu, H.; Moon, S.; Park, J.; Bak, S.; Ko, Y.; Youn, B.Y. The use of artificial intelligence in complementary and alternative medicine: A systematic scoping review. Front. Pharmacol., 2022, 13, 826044.
[http://dx.doi.org/10.3389/fphar.2022.826044] [PMID: 35431917]
[139]
Yang, X.; Wang, Y.; Byrne, R.; Schneider, G.; Yang, S. Concepts of artificial intelligence for computer-assisted drug discovery. Chem. Rev., 2019, 119(18), 10520-10594.
[http://dx.doi.org/10.1021/acs.chemrev.8b00728] [PMID: 31294972]
[140]
Choudhury, A. Toward an ecologically valid conceptual framework for the use of artificial intelligence in clinical settings: need for systems thinking, accountability, decision-making, trust, and patient safety considerations in safeguarding the technology and clinicians. JMIR Human Factors, 2022, 9(2), e35421.
[http://dx.doi.org/10.2196/35421] [PMID: 35727615]
[141]
Husnain, A. Revolutionizing pharmaceutical research: Harnessing machine learning for a paradigm shift in drug discovery. Int.j. multidiscip. sci. engineer., 2023, 2(2)
[142]
Ashton, J.J.; Mossotto, E.; Ennis, S.; Beattie, R.M. Personalising medicine in inflammatory bowel disease—current and future perspectives. Transl. Pediatr., 2019, 8(1), 56-69.
[http://dx.doi.org/10.21037/tp.2018.12.03] [PMID: 30881899]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy