Modeling and Analysis of Cancer Electrothermic Therapy Technique Based on a Digital Arm

Title:Modeling and Analysis of Cancer Electrothermic Therapy Technique Based on a Digital Arm

Volume: 18

Author(s): Jing Xu, Man Zhang, Jiangming Kuang, Yuping Qin and Shuang Zhang*

Affiliation:

• School of Artificial Intelligence, Neijiang Normal University, Neijiang, Sichuan, P.R. China
• NJNU-OMNISKY Smart Medical Engineering Applications Joint Laboratory, Neijiang Normal University, Neijiang, Sichuan, P.R. China
• Neijiang City Engineering Technology Research Center of Neurological Disease Information Interference, Neijiang Normal University, Neijiang, Sichuan, P.R. China

Abstract: Background: Intramuscular hemangioma (IMH) is a diffuse growth hemangioma located in the striated muscle, which is often overlooked due to its rarity.

Objective: This patent pertains to the integration of electroacupuncture with electrothermotherapy. By introducing electrical signals into the electroacupuncture system, electromagnetic heat is produced. This heat leads to the electrolysis and thermal destruction of tumor cells, enabling targeted and precise cancer treatment. Furthermore, the patent offers a theoretical foundation for exploring the distribution of electrical signals and the associated heat in arm muscles, ensuring accurate treatment.

Material and Method: To enable subsequent experimental validation, this patent integrates human anatomy and histological structure theory. The arm's geometric structure was derived from segmentation, reconstruction, and substantiation based on a digital human image dataset. Using the COMSOL Multiphysics 5.5 software, a semi-detailed finite element model was developed for the numerical simulation of electrothermotherapy. Within a time domain setting, a carrier signal of 1 MHz and 22 V was introduced to assess the distribution of electrical signals and the associated heat in the arm muscle.

Results: Electrical signals, electromagnetic heat, and tissue necrosis primarily concentrate in a spherical region within 10 mm of the exposed electroacupuncture tip, with the maximum coupling temperature reaching 250 °C at the tip. Time domain analysis revealed that the coupling temperature can rise within 1 min, sufficiently to cause complete tissue damage, with the tissue necrosis ratio reaching 100% in the same timeframe. While the coupling temperature continues to rise over time, the increment is modest. After 5 min, there is negligible temperature change, and once the tissue necrosis ratio reaches 100%, it remains consistent.

Conclusion: In the precision tumor treatment system utilizing electrothermotherapy, factors, such as the magnitude of the injected electrical signal, placement of the electroacupuncture tip, and treatment duration play a crucial role in the treatment's accuracy. This model delves into the treatment of intramuscular hemangiomas using electroacupuncture electrothermotherapy from two perspectives: spatial and temporal domains. It provides a theoretical foundation for precise electrothermotherapy in cancer treatment.

Cite this article as:

Xu Jing, Zhang Man, Kuang Jiangming, Qin Yuping and Zhang Shuang*, Modeling and Analysis of Cancer Electrothermic Therapy Technique Based on a Digital Arm, Recent Patents on Engineering 2024; 18 () : e041223224188 . https://dx.doi.org/10.2174/0118722121267419231118150634