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Mini-Reviews in Medicinal Chemistry

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ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

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Mini-Review Article

Alzheimer's Disease and Cancer: Common Targets

Author(s): Xueqing Yang, Jinlian Dai, Chenglong Wu and Zongliang Liu*

Volume 24, Issue 10, 2024

Published on: 21 November, 2023

Page: [983 - 1000] Pages: 18

DOI: 10.2174/0113895575263108231031132404

Price: $65

Abstract

There is growing epidemiologic evidence of an inverse association between cancer and AD. In addition, both cell survival and death are regulated by the same signaling pathways, and their abnormal regulation may be implicated in the occurrence and development of cancer and AD. Research shows that there may be a common molecular mechanism between cancer and AD. This review will discuss the role of GSK3, DAPK1, PP2A, P53 and CB2R in the pathogenesis of cancer and AD and describe the current research status of drug development based on these targets.

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