Preparation of Fluorous Aza-crown Ether with Two Bisfluorous Chain
Type Propionyl Groups: An Investigation of its Partition Ratios in
Fluorous Biphasic Systems and Recyclability During SN2-type
Acetoxylation Reactions

Takashi      Yamanoi; Kenji      Koike; Yoshiki      Oda

doi:10.2174/1570178620666230830125327

Abstract

In this study, a new fluorous aza-crown ether derivative (1) conjugated with two Bfp (bisfluorous chain type propionyl) groups was prepared; then, the partition ratios of 1 in biphasic systems using FC 72 and several organic solvents were investigated. Next, the activities of 1 in an FC 72/acetonitrile biphasic system were assessed via the S_N2-type acetoxylation reaction using 2- (bromomethyl)naphthalene and potassium acetate. Finally, the recyclability of 1 in a two-layer system based on its immobilization in an FC 72 solvent was examined during acetoxylation reactions.

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DOI https://dx.doi.org/10.2174/1570178620666230830125327	Print ISSN 1570-1786
Publisher Name Bentham Science Publisher	Online ISSN 1875-6255

Letters in Organic Chemistry

Preparation of Fluorous Aza-crown Ether with Two Bisfluorous Chain Type Propionyl Groups: An Investigation of its Partition Ratios in Fluorous Biphasic Systems and Recyclability During S_N2-type Acetoxylation Reactions

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Letters in Organic Chemistry

Preparation of Fluorous Aza-crown Ether with Two Bisfluorous Chain Type Propionyl Groups: An Investigation of its Partition Ratios in Fluorous Biphasic Systems and Recyclability During SN2-type Acetoxylation Reactions

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Preparation of Fluorous Aza-crown Ether with Two Bisfluorous Chain Type Propionyl Groups: An Investigation of its Partition Ratios in Fluorous Biphasic Systems and Recyclability During S_N2-type Acetoxylation Reactions

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