Abstract
Hesperidin is one of the most well-known, naturally occurring flavonoids with antioxidant and anti-inflammatory effect, occurring in high concentrations in citrus fruits. Citrus fruits and juices are widely consumed worldwide and are readily available dietary sources for their intake. Its use has been associated with a great number of health benefits, including antioxidant, antibacterial, antimicrobial, antiinflammatory and anti-carcinogenic properties. Due to its biological activities, hesperidin is often used in the food, cosmetic and pharmaceutical industries. Supplements containing hesperidin, alone or in combination with other citrus bioflavonoids, are commercially available. The utilization of hesperidin can be used for the production of novel nutraceuticals or for the improvement of older ones. This piece of review aims to discuss the various diversified aspects of the naturally occurring bioflavonoid hesperidin.
Graphical Abstract
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