Abstract
Background: One of the most effective ways to prevent cervical cancer is to identify the risk factors for the disease.
Objective: The purpose of this research was to determine the risk factors for cervical cancer in women in Iran.
Methods: This was a matched case-control study. 105 participants (35 patients with cervical cancer and 70 healthy women) were selected from the registered patients and women attending a women’s specialized hospital in Hamadan, Iran. One case was matched to 2 controls by age (±3 years). Demographic and clinical data were collected using a semi-structured questionnaire. Conditional multivariate logistic regression model and STATA 11 software were used for data analysis.
Results: The mean age of women in the case and control group were 58.02(12.32) and 58.11(12.25) years (p = 0.486), respectively. Patients had lower education levels (p = 0.037), lower economic status (p˂0.001), and lower spouse education levels (p = 0.009). The results showed OCP users were 8.79 times more likely to develop cervical cancer than women who do not use OCP (p = 0.007), and the probability of cervical cancer in women increased by 8.33 times (<0.001) with decreasing each level of socio-economic status.
Conclusion: The results of the present study showed low economic status, and a history of using oral contraceptive pills are risk factors for cervical cancer.
Graphical Abstract
[http://dx.doi.org/10.5114/wo.2019.84112] [PMID: 31061631]
[http://dx.doi.org/10.22038/ijogi.2016.6863]
[http://dx.doi.org/10.1136/ijgc-2021-003014] [PMID: 34725203]
[http://dx.doi.org/10.3389/fpubh.2020.552028] [PMID: 33553082]
[http://dx.doi.org/10.1186/s13027-018-0178-5] [PMID: 29416557]
[http://dx.doi.org/10.1016/j.canep.2018.01.014] [PMID: 29414636]
[http://dx.doi.org/10.1371/journal.pone.0254663] [PMID: 34265004]
[http://dx.doi.org/10.21147/j.issn.1000-9604.2020.06.05] [PMID: 33446995]
[http://dx.doi.org/10.4103/apjon.apjon_73_18] [PMID: 31259228]
[http://dx.doi.org/10.1371/journal.pone.0218762] [PMID: 31246997]
[http://dx.doi.org/10.1097/CEJ.0000000000000704] [PMID: 34267110]
[http://dx.doi.org/10.18632/oncotarget.21743] [PMID: 29228605]
[PMID: 20843147]
[http://dx.doi.org/10.1097/01.AOG.0000514990.39187.95]
[http://dx.doi.org/10.22038/ijogi.2011.5799]
[http://dx.doi.org/10.1016/j.whi.2017.09.008] [PMID: 29108988]
[http://dx.doi.org/10.1016/j.cegh.2017.10.001]
[http://dx.doi.org/10.7314/APJCP.2014.15.14.5517] [PMID: 25081657]
[http://dx.doi.org/10.1016/j.ajog.2017.02.002]
[http://dx.doi.org/10.1111/jog.13291] [PMID: 28759170]
[http://dx.doi.org/10.1080/02841860152703481] [PMID: 11859985]
[http://dx.doi.org/10.1093/ije/31.1.202] [PMID: 11914322]
[http://dx.doi.org/10.1001/jama.2013.281053] [PMID: 24141714]