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Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Case Report

Nontuberculous Mycobacterial Infection Mimicking Lung Cancer in a Patient with Usual Interstitial Pneumonia Pattern Interstitial Lung Disease: A Case Report

Author(s): Chaebin Lee, Jongsoo Park*, Jae-Kwang Lim, Jongmin Park and Byunggeon Park

Volume 20, 2024

Published on: 24 August, 2023

Article ID: e250723219034 Pages: 4

DOI: 10.2174/1573405620666230725093800

Price: $65

Abstract

Background: It has been reported that structure damage in the parenchymal lung disease such as idiopathic pulmonary fibrosis (IPF) is associated with high susceptibility to nontuberculous mycobacterial (NTM) infection. Radiologic features of NTM lung disease in destructive lung parenchyma can be atypical, which can cause confusion with other diseases including malignancy. Prompt and accurate identification of newly developed lesions in the follow-up computed tomography (CT) of IPF patients is challenging but crucial.

Case Report: We reported a case of an NTM infection in a patient with IPF, manifested as a mass-like consolidation with cavitation on chest CT, mimicking lung cancer.

Conclusion: Being aware of the unusual radiologic features of NTM lung disease in IPF patients can be useful in the differential diagnosis of newly detected lesions.

[1]
Hong SJ, Kim TJ, Lee JH, Park JS. Nontuberculous mycobacterial pulmonary disease mimicking lung cancer. Medicine 2016; 95(26): e3978.
[http://dx.doi.org/10.1097/MD.0000000000003978] [PMID: 27367996]
[2]
Hwang HJ, Kim MY, Shim TS, Kim DS. Nontuberculous mycobacterial pulmonary infection in patients with idiopathic interstitial pneumonias: Comparison with patients without idiopathic interstitial pneumonias. J Comput Assist Tomogr 2014; 38(6): 972-8.
[http://dx.doi.org/10.1097/RCT.0000000000000144] [PMID: 25162293]
[3]
Odashima K, Kagiyama N, Kanauchi T, Ishiguro T, Takayanagi N. Incidence and etiology of chronic pulmonary infections in patients with idiopathic pulmonary fibrosis. PLoS One 2020; 15(4): e0230746.
[http://dx.doi.org/10.1371/journal.pone.0230746] [PMID: 32243456]
[4]
Martinez S, McAdams HP, Batchu CS. The many faces of pulmonary nontuberculous mycobacterial infection. AJR Am J Roentgenol 2007; 189(1): 177-86.
[http://dx.doi.org/10.2214/AJR.07.2074] [PMID: 17579169]
[5]
Park B, Park J. Atypical presentation of nontuberculous mycobacterial pulmonary infection in a patient with interstitial lung abnormality: A case report. Eur J Radiol Open 2021; 8: 100353.
[http://dx.doi.org/10.1016/j.ejro.2021.100353] [PMID: 34056053]
[6]
Chung MJ, Goo JM, Im JG. Pulmonary tuberculosis in patients with idiopathic pulmonary fibrosis. Eur J Radiol 2004; 52(2): 175-9.
[http://dx.doi.org/10.1016/j.ejrad.2003.11.017] [PMID: 15489076]
[7]
Lee Y, Song J-W, Chae EJ, et al. CT findings of pulmonary non-tuberculous mycobacterial infection in non-AIDS immunocompromised patients: A case-controlled comparison with immunocompetent patients. Br J Radiol 2013; 86(1024): 20120209.
[http://dx.doi.org/10.1259/bjr.20120209] [PMID: 23440166]
[8]
Bjoraker JA, Ryu JH, Edwin MK, et al. Prognostic significance of histopathologic subsets in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 1998; 157(1): 199-203.
[http://dx.doi.org/10.1164/ajrccm.157.1.9704130] [PMID: 9445300]
[9]
Oh SY, Kim MY, Hwang HJ, et al. Newly detected pulmonary nontuberculous mycobacterial infection and peripheral lung cancers in patients during follow-up of idiopathic interstitial pneumonia: comparison of CT findings. Medicine 2015; 94(13): e691.
[http://dx.doi.org/10.1097/MD.0000000000000691] [PMID: 25837763]
[10]
Hubbard R, Venn A, Lewis S, Britton J. Lung cancer and cryptogenic fibrosing alveolitis. A population-based cohort study. Am J Respir Crit Care Med 2000; 161(1): 5-8.
[http://dx.doi.org/10.1164/ajrccm.161.1.9906062] [PMID: 10619790]
[11]
Matsushita H, Tanaka S, Saiki Y, et al. Iung cancer associated with usual interstitial pneumonia. Pathol Int 1995; 45(12): 925-32.
[http://dx.doi.org/10.1111/j.1440-1827.1995.tb03417.x] [PMID: 8808297]
[12]
Ozawa Y, Suda T, Naito T, et al. Cumulative incidence of and predictive factors for lung cancer in IPF. Respirology 2009; 14(5): 723-8.
[http://dx.doi.org/10.1111/j.1440-1843.2009.01547.x] [PMID: 19659650]
[13]
Griffith DE, Aksamit T, Brown-Elliott BA, et al. An official ATS/IDSA statement: Diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med 2007; 175(4): 367-416.
[http://dx.doi.org/10.1164/rccm.200604-571ST] [PMID: 17277290]
[14]
O’Brien RJ, Geiter LJ, Snider DE Jr. The epidemiology of nontuberculous mycobacterial diseases in the United States. Results from a national survey. Am Rev Respir Dis 1987; 135(5): 1007-14.
[http://dx.doi.org/10.1164/arrd.1987.135.5.1007] [PMID: 3579001]

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