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New Emirates Medical Journal

Editor-in-Chief
ISSN (Online): 0250-6882

Case Report

Large Right Ventricular Hemangioma Presented as Acute Pulmonary Embolism at Two Weeks Post-COVID19 Vaccination: A Case Report

Author(s): Essam Hassan*, Amr A. Arafat, Saeed Alahmadi, Asadullah Roomi and Adam I Adam

Volume 4, Issue 2, 2023

Published on: 13 June, 2023

Article ID: e120423215686 Pages: 3

DOI: 10.2174/0250688204666230412085052

Price: $0

Abstract

Background: Right ventricular hemangioma is very rare. Corona Virus disease (COVID-19) and vaccination were documented to cause diverse thromboembolic phenomena.

Case Presentation: We report a large right ventricular hemangioma presented as acute pulmonary embolism two weeks after COVID-19 vaccination associated with acute kidney injury and significantly elevated Interleukin-6 (IL-6). There was no thrombocytopenia; therefore, the diagnosis of vaccine-induced immune thrombotic thrombocytopenia (VIIT) was deemed unlikely. The patient underwent emergency cardiac surgery. The mass was excised through a right atriotomy, and tricuspid annuloplasty was done. IL-6 normalized after six days with resolution of acute kidney injury.

Conclusion: Pulmonary embolism is a rare presentation of the right ventricular hemangioma, and COVID-19 vaccination could play a role in this presentation. Cardiac hemangioma could be associated with high IL-6 that resolves with excision.

[1]
Li W, Teng P, Xu H, Ma L, Ni Y. Cardiac hemangioma: A comprehensive analysis of 200 cases. Ann Thorac Surg 2015; 99(6): 2246-52.
[http://dx.doi.org/10.1016/j.athoracsur.2015.02.064] [PMID: 25921258]
[2]
Krishna A, Constantin M. Rare case of intramyocardial right ventricular outflow tract (RVOT) hemangioma. J Am Coll Cardiol 2019; 12: 73.
[3]
Malas MB, Naazie IN, Elsayed N, Mathlouthi A, Marmor R, Clary B. Thromboembolism risk of COVID-19 is high and associated with a higher risk of mortality: A systematic review and meta-analysis. EClinicalMedicine 2020; 29-30: 100639.
[http://dx.doi.org/10.1016/j.eclinm.2020.100639] [PMID: 33251499]
[4]
Su H, Lei CT, Zhang C. Interleukin-6 signaling pathway and its role in kidney disease: An update. Front Immunol 2017; 8: 405.
[http://dx.doi.org/10.3389/fimmu.2017.00405] [PMID: 28484449]
[5]
Li X, Chen Y, Liu J, et al. Cardiac magnetic resonance imaging of primary cardiac tumors. Quant Imaging Med Surg 2020; 10(1): 294-313.
[http://dx.doi.org/10.21037/qims.2019.11.13] [PMID: 31956550]
[6]
Bussel DBC. SARS-CoV-2 vaccine-induced immune thrombotic thrombocytopenia. N Engl J Med 2021; 384(23): 2254-6.
[http://dx.doi.org/10.1056/NEJMe2106315] [PMID: 33861524]
[7]
Mendoza CE, Rosado MF, Pacheco P. Interleukin-6 production and recurrent cardiac myxoma. J Thorac Cardiovasc Surg 2001; 121(2): 395-6.
[http://dx.doi.org/10.1067/mtc.2001.109704] [PMID: 11174750]
[8]
Neiva KG, Warner KA, Campos MS, et al. Endothelial cell-derived interleukin-6 regulates tumor growth. BMC Cancer 2014; 14(1): 99.
[http://dx.doi.org/10.1186/1471-2407-14-99] [PMID: 24533454]

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