Login Register Cart 0
Generic placeholder image

Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

Study on the Specific Expression of Infrared Radiation Temperature on the Body Surface of Acupoint in Rats with Chronic Myocardial Ischemic Injury

Author(s): Jian Xiong, Xiang Li, Hongjuan Fu, Xinye Luo, Xiao Li, Yanrong Ren, Xueying Liu, Qianhua Zheng, Wenchuan Qi* and Fanrong Liang*

Volume 19, Issue 13, 2023

Published on: 27 March, 2023

Article ID: e170223213763 Pages: 11

DOI: 10.2174/1573405619666230217120343

Price: $65

Abstract

Background: Infrared thermal imaging technology was used to observe the changes in infrared radiation temperature at acupoints in rats caused by chronic myocardial ischemia injury.

Objective: This study aims to compare the difference of body surface infrared radiation temperature information of three groups of acupoints: bilateral Neiguan (PC6), bilateral Yanglingquan (GB33), and bilateral Sham Acupoints (SA) in the pathological state of myocardial ischemia injury, and to explore the relationship between acupoints and viscera state.

Methods: SPF adult Wistar male rats (n = 20) were randomly divided into a control (CTL; n = 10) and an isoproterenol group (ISO; n = 10). Chronic myocardial injury was induced in rats by subcutaneous injection of isoproterenol hydrochloride for 14 d. On the second day after the establishment of the model, the serum levels of cardiac troponin (cTnI) and creatine kinase isoenzyme (CK-MB) were measured by enzyme-linked immunosorbent assay (ELISA). The morphological changes of the myocardial tissue in the two groups were observed by hematoxylin-eosin (HE) staining and their pathological scores were evaluated, which was then used to determine the myocardial ischemic injury. Two days before and after the establishment of the model, the electrocardiograms (ECG) of the two groups of rats were recorded by the (ECG) data acquisition system, and the infrared thermal imaging platform was used to detect the temperature of the six acupoints.

Results: 1. After subcutaneous injection of isoproterenol hydrochloride for 14 days, the ST segment of the ECG decreased in the ISO group compared with that of the CTL group; 2. Myocardial tissue injury was serious in the ISO group compared to the CTL group; 3. Serum cTn-I and CK-MB were significantly increased (P <0 01) in the ISO group, compared to that in the CTL group; 4. The infrared radiation temperature on the body surface of bilateral Neiguan (PC6) acupoints decreased significantly in the ISO group, compared to that of the CTL group.

Conclusion: Infrared thermal imaging technology can be used to detect the changes in the energy state of acupoints. Chronic myocardial ischemic injury can cause a decrease in IR temperature on the body surface of bilateral Neiguan (PC6) acupoints, suggesting that visceral diseases can lead to changes in the energy metabolism of acupoints.

Graphical Abstract

[1]
World health statistics 2021: Monitoring health for the SDGs, sustainable development goals. 2021.
[2]
Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics-2016 update: A report from the American Heart Association. Circulation 2016; 133(4): e38-e360.
[http://dx.doi.org/10.1161/CIR.0000000000000350] [PMID: 26673558]
[3]
Stewart RAH, Held C, Krug-Gourley S, et al. Cardiovascular and lifestyle risk factors and cognitive function in patients with stable coronary heart disease. J Am Heart Assoc 2019; 8(7): e010641.
[http://dx.doi.org/10.1161/JAHA.118.010641] [PMID: 30897999]
[4]
Pencina MJ, Navar AM, Wojdyla D, et al. Quantifying importance of major risk factors for coronary heart disease. Circulation 2019; 139(13): 1603-11.
[http://dx.doi.org/10.1161/CIRCULATIONAHA.117.031855] [PMID: 30586759]
[5]
Yusuf S, Joseph P, Rangarajan S, et al. Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): A prospective cohort study. Lancet 2020; 395(10226): 795-808.
[http://dx.doi.org/10.1016/S0140-6736(19)32008-2] [PMID: 31492503]
[6]
Kostić T, Deljanin Ilić M, Perišić Z, et al. Design and development oI novel therapeutics for coronary heart disease treatment based on cholesteryl ester transfer protein inhibitiorr in silico approach. J Biomol Struct Dyn 2020; 38(8): 2304-13.
[http://dx.doi.org/10.1080/07391102.2019.1630319] [PMID: 31215331]
[7]
Menotti A, Puddu PE, Kromhout D, Kafatos A, Tolonen H. Coronary heart disease mortality trends during 50 years as explained by risk factor changes: The European cohorts of the Seven Countries Study. Eur J Prev Cardiol 2020; 27(9): 988-98.
[http://dx.doi.org/10.1177/2047487318821250] [PMID: 30614262]
[8]
Richter A, Herlitz J, Hjalmarson Å. Effect of acupuncture in patients with angina pectoris. Eur Heart J 1991; 12(2): 175-8.
[http://dx.doi.org/10.1093/oxfordjournals.eurheartj.a059865] [PMID: 2044550]
[9]
Zhang Z, Chen M, Zhang L, et al. Meta-analysis of acupuncture therapy for the treatment of stable angina pectoris. Int J Clin Exp Med 2015; 8(4): 5112-20.
[PMID: 26131084]
[10]
Yang M, Sun M, Du T, et al. The efficacy of acupuncture for stable angina pectoris: A systematic review and meta-analysis. Eur J Prev Cardiol 2021; 28(13): 1415-25.
[PMID: 31529993]
[11]
Ho FM, Huang PJ, Lo HM, et al. Effect of acupuncture at nei-kuan on left ventricular function in patients with coronary artery disease. Am J Chin Med 1999; 27(2): 149-56.
[http://dx.doi.org/10.1142/S0192415X99000197] [PMID: 10467449]
[12]
Sun M, Yang M, Rong J, et al. Trigger points and sensitized acupoints: Same book, different covers? Acupunct Herb Med 2021; 1(2): 74-80.
[http://dx.doi.org/10.1097/HM9.0000000000000018]
[13]
Li H, Shen X, Ying J, et al. Patients with clinical/radiological hyperplasia of mammary glands show pathological persistence of temperature of skin points. Anticancer Res 2009; 29(11): 4697-702.
[PMID: 20032422]
[14]
Li H, Ying J, Shen X, et al. Infrared radiation temperature comparison on body surface of points between healthy people and patients with hyperplasia of mammary glands. J Acupunct Tuina Sci 2008; 6(4): 215-8.
[http://dx.doi.org/10.1007/s11726-008-0215-9]
[15]
Shen X, Ding G, Deng H, et al. Infrared radiation spectrum of acupuncture point on patients with coronary heart disease. Am J Chin Med 2008; 36(2): 211-8.
[http://dx.doi.org/10.1142/S0192415X08005722] [PMID: 18457356]
[16]
Du J, Zhou L, Wu H, et al. Study on effect of voltage-gated calcium channel protein in meridian tissue cells exciting conduction. Zhongguo Zhen Jiu 2016; 36(10): 1051-5.
[PMID: 29231525]
[17]
Du J, Zhou LH. Formation mechanism of high-energy metabolism along meridians Zhongguo Zhenjiu 2014; 34(11): 1119-21.
[PMID: 25675579]
[18]
Jiang H, Cui XJ, Yu Z. Meridian essence: Modern thought. Chin J Integr Med 2013; 19(6): 471-4.
[http://dx.doi.org/10.1007/s11655-013-1322-5] [PMID: 23264000]
[19]
Ye X, Ren Y, Chen Y, Chen J, Tang X, Zhang ZA. “4D” systemic view on meridian essence: Substantial, functional, chronological and cultural attributes. J Integr Med 2022; 20(2): 96-103.
[http://dx.doi.org/10.1016/j.joim.2021.11.006] [PMID: 34896049]
[20]
Yang M, Han J. Review and analysis on the meridian research of China over the past sixty years. Chin J Integr Med 2015; 21(5): 394-400.
[http://dx.doi.org/10.1007/s11655-015-2168-4] [PMID: 25935144]
[21]
de Melo DP, Bento PM, Peixoto LR, Martins SKLD, Martins CC. Is infrared thermography effective in the diagnosis of temporomandibular disorders? A systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol 2019; 127(2): 185-92.
[http://dx.doi.org/10.1016/j.oooo.2018.09.006] [PMID: 30482738]
[22]
Xiong J, Wang Z, Ruan M, et al. Current status of neuroimaging research on the effects of acupuncture: A bibliometric and visual analyses. Complement Ther Med 2022; 71: 102877.
[http://dx.doi.org/10.1016/j.ctim.2022.102877] [PMID: 35998753]
[23]
Vreugdenburg TD, Willis CD, Mundy L, Hiller JE. A systematic review of elastography, electrical impedance scanning, and digital infrared thermography for breast cancer screening and diagnosis. Breast Cancer Res Treat 2013; 137(3): 665-76.
[http://dx.doi.org/10.1007/s10549-012-2393-x] [PMID: 23288346]
[24]
de Camargo VMB, Ulbricht L, Coninck JCP, Ripka WL, Gamba HR. Thermography as an aid for the complementary diagnosis of nodules in the thyroid gland. Biomed Eng Online 2022; 21(1): 41.
[http://dx.doi.org/10.1186/s12938-022-01009-3] [PMID: 35761269]
[25]
der Strasse W, Campos DP, Mendonça CJA, Soni JF, Mendes J, Nohama P. Detecting bone lesions in the emergency room with medical infrared thermography. Biomed Eng Online 2022; 21(1): 35.
[http://dx.doi.org/10.1186/s12938-022-01005-7] [PMID: 35698224]
[26]
Qu Y, Meng Y, Fan H, Xu RX. Low-cost thermal imaging with machine learning for non-invasive diagnosis and therapeutic monitoring of pneumonia. Infrared Phys Technol 2022; 123: 104201.
[http://dx.doi.org/10.1016/j.infrared.2022.104201] [PMID: 35599723]
[27]
Fiscal MRC, Treviño V, Treviño LJR, et al. COVID-19 classification using thermal images. J Biomed Opt 2022; 27(5): 056003.
[http://dx.doi.org/10.1117/1.JBO.27.5.056003] [PMID: 35585679]
[28]
Verstockt J, Verspeek S, Thiessen F, Tjalma WA, Brochez L, Steenackers G. Skin cancer detection using infrared thermography: Measurement setup, procedure and equipment. Sensors (Basel) 2022; 22(9): 3327.
[http://dx.doi.org/10.3390/s22093327] [PMID: 35591018]
[29]
Vergilio MM, Gomes G, Aiello LM, et al. Evaluation of skin using infrared thermal imaging for dermatology and aesthetic applications. J Cosmet Dermatol 2022; 21(3): 895-904.
[http://dx.doi.org/10.1111/jocd.14748] [PMID: 35041761]
[30]
Li L, Li J, Drum BM, et al. Loss of AKAP150 promotes pathological remodelling and heart failure propensity by disrupting calcium cycling and contractile reserve. Cardiovasc Res 2017; 113(2): 147-59.
[http://dx.doi.org/10.1093/cvr/cvw221] [PMID: 27856611]
[31]
Fu Y, Li J, Wu S, Wang H. Electroacupuncture pretreatment promotes angiogenesis via hypoxia-inducible factor 1α and vascular endothelial growth factor in a rat model of chronic myocardial ischemia. Acupunct Med 2021; 39(4): 367-75.
[http://dx.doi.org/10.1177/0964528420938378] [PMID: 32811184]
[32]
Javidanpour S, Dianat M, Aliakbari FR, Sarkaki A. The effects of olive leaf extract and 28 days forced treadmill exercise on electrocardiographic parameters in rats. J Res Med Sci 2018; 23: 108.
[PMID: 30693043]
[33]
Joukar S, Najafipour H, Khaksari M, et al. The effect of saffron consumption on biochemical and histopathological heart indices of rats with myocardial infarction. Cardiovasc Toxicol 2010; 10(1): 66-71.
[http://dx.doi.org/10.1007/s12012-010-9063-1] [PMID: 20119744]
[34]
Yi GUO. Experimental acupuncture. Beijing: China Traditional Chinese Medicine Press 2016; pp. 287-9.
[35]
Yawen LU, Bo JI, Jian DAI, et al. Effects of electro-acupuncture and stimulation frequency of different frequencies on the amount of blood perfusion in the skin of inner and non-trans-acupuncture points in rats with myocardial ischemia. J Beijing Uni Trad Chinese Med 2016; 29(12): 1041-7.
[36]
Sun Q, Kang Z, Cai J, et al. Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats. Exp Biol Med (Maywood) 2009; 234(10): 1212-9.
[http://dx.doi.org/10.3181/0812-RM-349] [PMID: 19596825]
[37]
Feng Y, Xie Y, Wang H, et al. A modified rabbit model of reperfused myocardial infarction for cardiac MR imaging research. Int J Cardiovasc Imaging 2009; 25(3): 289-98.
[http://dx.doi.org/10.1007/s10554-008-9393-2] [PMID: 19043805]
[38]
Wu YX. The Study of forceps operation on making reperfusion in- jury of ischemic myocardium model. Guangxi Med J 2000; 22(3): 429-30.
[39]
Guo HS, Deng HQ, Liu LP, et al. A study of a new animal model of experimental coronary artery spasm. Chin Heart J 1994; 6(4): 205-8.
[40]
Romson JL, Haack DW, Lucchesi BR. Electrical induction of coronary artery thrombosis in the ambulatory canine: A model for evaluation of anti-thrombotic agents. Thromb Res 1980; 17(6): 841-53.
[http://dx.doi.org/10.1016/0049-3848(80)90249-2] [PMID: 7404490]
[41]
Ohtsuka S, Ishikawa K, Suzuki S, et al. A porcine model of ischemic heart failure produced by chronic placement of a tube in a coronary artery. Eur J Heart Fail 2003; 5(5): 591-8.
[http://dx.doi.org/10.1016/S1388-9842(03)00103-X] [PMID: 14607196]
[42]
Reffelmann T, Sensebat O, Birnbaum Y, et al. A novel minimal-invasive model of chronic myocardial infarction in swine. Coron Artery Dis 2004; 15(1): 7-12.
[http://dx.doi.org/10.1097/00019501-200402000-00002] [PMID: 15201615]
[43]
Lassaletta AD, Chu LM, Robich MP, et al. Overfed Ossabaw swine with early stage metabolic syndrome have normal coronary collateral development in response to chronic ischemia. Basic Res Cardiol 2012; 107(2): 243.
[http://dx.doi.org/10.1007/s00395-012-0243-y] [PMID: 22231675]
[44]
Zhang QY, Wang ZH, Li XB, Yin LH, Li JB, Wei M. The establishment of animal model with coronary microembolization suitable for long-term obser- vation by using endovascular microcatheter technique. J Inter Radiol 2009; 18(12): 920-2.
[45]
Liu JX, Yu Z, Li XZ. Study of chronic myocardial ischemic model in miniature swines induced by rich fat feed and LAD balloon injury. Pharmacol Clin Chin Mater Med 2008; 24(3): 108-11.
[46]
Tsai SR, Hamblin MR. Biological effects and medical applications of infrared radiation. J Photochem Photobiol B 2017; 170: 197-207.
[http://dx.doi.org/10.1016/j.jphotobiol.2017.04.014] [PMID: 28441605]
[47]
Mota-Rojas D, Olmos-Hernández A, Verduzco-Mendoza A, et al. Infrared thermal imaging associated with pain in laboratory animals. Exp Anim 2021; 70(1): 1-12.
[http://dx.doi.org/10.1538/expanim.20-0052] [PMID: 32848100]
[48]
McVeigh ER. Emerging imaging techniques. Circ Res 2006; 98(7): 879-86.
[http://dx.doi.org/10.1161/01.RES.0000216870.73358.d9] [PMID: 16614313]
[49]
Tavares IM, Vardasca R, Cera N, et al. A review of infrared thermography as applied to human sexual psychophysiology. Int J Psychophysiol 2018; 133: 28-40.
[http://dx.doi.org/10.1016/j.ijpsycho.2018.09.001] [PMID: 30208297]
[50]
Xiao C, Hu Y. The role of thermal imaging cameras in the diagnosis of coronary heart disease. Chinese Journal of Misdiagnosis 2009; 9(1): 36-7.
[51]
Wei JZ, Shen XY, Ding GH, Zhao L, Zhou Y. Study on spontaneous infrared radiation spectroscopy of Taiyuan Cave. J Shang Uni Trad Chin Med 2004; (04): 33-5.
[52]
Liu HP, Shen XY, Deng HP, et al. Infrared radiation spectroscopy of Laogong acupuncture points in patients with coronary heart disease. Shanghai J Tradit Chinese Med 2004; (04): 52-3.
[53]
Deng HP, Shen XY, Ding GH, et al. Infrared radiation spectroscopy detection of Shenmen acupuncture points in patients with coronary heart disease. Shanghai Journal of Acupuncture 2004; (11): 31-4.
[54]
Zhang YQ, Ding GH, Shen XY, et al. Differences in infrared radiation spectra of acupuncture points in normal and coronary heart patients. Zhongguo Zhenjiu 2004; (12): 34-7.
[55]
Ying J, Shen XY, Liu HP, et al. Comparison of infrared radiation spectra of patients with coronary heart disease and normal people. Zhejiang Journal of Traditional Chinese Medicine 2005; (03): 11-2.
[56]
Liu HP, Shen XY, Ding GH, Deng HP, Wei JZ. Study on pathological information of infrared radiation spectroscopy in patients with coronary heart disease. J Tradit Chin Med 2005; (11): 41-2.
[57]
Zhou Y, Shen XY, Ding GH, Deng HP, Wei JZ, Yin J. A comparative study of infrared radiation spectra in patients with coronary heart disease and normal people in Taibai acupoint. J Tradit Chin Med 2006; 25(6): 653-5.
[58]
Shen X-Y, Ding G-H, Deng H-P, et al. Analysis on pathological information of infrared radiation spectrums at acupuncture point neiguan (PC6) for patients with coronary heart disease. J Infr milli wave 2006; (06): 443-6.
[59]
Zhao L, Shen XY, Ding GH, et al. Study on infrared radiation spectrum of Taixi acupoint in normal people and patients with coronary heart disease. Chinese J Basic Med Tradit Chinese Medicine 2006; (06): 461-2.
[60]
Tu M, Jiang Y, Yu J, et al. Acupuncture for treating chronic stable angina pectoris associated anxiety and depression: A systematic review and meta-analysis. Complement Ther Clin Pract 2021; 45: 101484.
[http://dx.doi.org/10.1016/j.ctcp.2021.101484] [PMID: 34517216]
[61]
Liu Y, Meng H, Khurwolah MR, et al. Acupuncture therapy for the treatment of stable angina pectoris: An updated meta-analysis of randomized controlled trials. Complement Ther Clin Pract 2019; 34: 247-53.
[http://dx.doi.org/10.1016/j.ctcp.2018.12.012] [PMID: 30712735]
[62]
Peng Q, Yao X, Xiang J, Wang Y, Lin X. Acupuncture for hyperlipidemia. Medicine (Baltimore) 2018; 97(50): e13041.
[http://dx.doi.org/10.1097/MD.0000000000013041] [PMID: 30557963]
[63]
Li X, Jia HX, Yin DQ, Zhang ZJ. Acupuncture for metabolic syndrome: Systematic review and meta-analysis. Acupunct Med 2021; 39(4): 253-63.
[http://dx.doi.org/10.1177/0964528420960485] [PMID: 33032446]
[64]
Liu M, Zhang Q, Jiang S, et al. Warm-needling acupuncture and medicinal cake-separated moxibustion for hyperlipidemia: Study protocol for a randomized controlled trial. Trials 2017; 18(1): 310.
[http://dx.doi.org/10.1186/s13063-017-2029-x] [PMID: 28693531]
[65]
Liu J, Li S, Liu L, et al. Conventional acupuncture for cardiac arrhythmia: A systematic review of randomized controlled trials. Chin J Integr Med 2018; 24(3): 218-26.
[http://dx.doi.org/10.1007/s11655-017-2753-9] [PMID: 28432528]
[66]
Li JL, Wang LQ, Zhang N, et al. Acupuncture as an adjunctive therapy for arrhythmia: A Delphi expert consensus survey. Cardiovasc Diagn Ther 2021; 11(5): 1067-79.
[http://dx.doi.org/10.21037/cdt-21-201] [PMID: 34815957]
[67]
Wang L, Yu CC, Li J, Tian Q, Du YJ. Mechanism of action of acupuncture in obesity: A perspective from the hypothalamus. Front Endocrinol (Lausanne) 2021; 12: 632324.
[http://dx.doi.org/10.3389/fendo.2021.632324] [PMID: 33868169]
[68]
Zhang RQ, Tan J, Li FY, Ma YH, Han LX, Yang XL. Acupuncture for the treatment of obesity in adults: A systematic review and meta-analysis. Postgrad Med J 2017; 93(1106): 743-51.
[http://dx.doi.org/10.1136/postgradmedj-2017-134969] [PMID: 28689171]
[69]
Zhong YM, Luo XC, Chen Y, et al. Acupuncture versus sham acupuncture for simple obesity: A systematic review and meta-analysis. Postgrad Med J 2020; 96(1134): 221-7.
[http://dx.doi.org/10.1136/postgradmedj-2019-137221] [PMID: 32015189]
[70]
Zhang X, Val-Laillet D. Obesity animal models for acupuncture and related therapy research studies. Evid Based Complement Alternat Med 2021; 2021: 1-29.
[http://dx.doi.org/10.1155/2021/6663397] [PMID: 34630614]
[71]
Wen J, Chen X, Yang Y, et al. Acupuncture medical therapy and its underlying mechanisms: A systematic review. Am J Chin Med 2021; 49(1): 1-23.
[http://dx.doi.org/10.1142/S0192415X21500014] [PMID: 33371816]
[72]
Fan X, Yu M, Fu SP, Zhuang Y, Lu S. Effectiveness of acupuncture in treatment of simple obesity in animal models: A systematic review and meta-analysis. Evid Based Complement Alternat Med 2019; 2019: 1-36.
[http://dx.doi.org/10.1155/2019/5459326] [PMID: 31391859]
[73]
Tuǧrul Cabıoǧlu M, Ergene N. Electroacupuncture therapy for weight loss reduces serum total cholesterol, triglycerides, and LDL cholesterol levels in obese women. Am J Chin Med 2005; 33(4): 525-33.
[http://dx.doi.org/10.1142/S0192415X05003132] [PMID: 16173527]
[74]
Cabioglu MT, Gündoǧan N, Ergene N. The efficacy of electroacupuncture therapy for weight loss changes plasma lipoprotein A, apolipoprotein A and apolipoprotein B levels in obese women. Am J Chin Med 2008; 36(6): 1029-39.
[http://dx.doi.org/10.1142/S0192415X08006430] [PMID: 19051333]
[75]
Cabıoğlu MT, Ergene N. Changes in levels of serum insulin, C-Peptide and glucose after electroacupuncture and diet therapy in obese women. Am J Chin Med 2006; 34(3): 367-76.
[http://dx.doi.org/10.1142/S0192415X06003904] [PMID: 16710886]
[76]
Qi W, Li X, Ren Y, et al. Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis. Chin Med 2022; 17(1): 57.
[http://dx.doi.org/10.1186/s13020-022-00615-6] [PMID: 35578250]
[77]
Guo HH, Jing XY, Chen H, Xu HX, Zhu BM. STAT3 but Not STAT5 Contributes to the Protective Effect of Electroacupuncture Against Myocardial Ischemia/Reperfusion Injury in Mice. Front Med (Lausanne) 2021; 8: 649654.
[http://dx.doi.org/10.3389/fmed.2021.649654] [PMID: 34307396]
[78]
Han YL, Chen S, Peng X. Electroacupuncture Pretreatment at Neiguan (PC6) attenuates autophagy in rats with myocardial ischemia reperfusion through the phosphatidylinositol 3-kinase-Akt-mammalian target of rapamycin pathway. J Tradit Chin Med 2021; 41(3): 455-62.
[PMID: 34114404]
[79]
Wang C, Liang X, Yu Y, Li Y, Wen X, Liu M. Electroacupuncture pretreatment alleviates myocardial injury through regulating mitochondrial function. Eur J Med Res 2020; 25(1): 29.
[http://dx.doi.org/10.1186/s40001-020-00431-4] [PMID: 32738910]
[80]
Yang Q, Mao H, Chen X, et al. Neiguan (PC6)-based acupuncture pretreatment for myocardial ischemia reperfusion injury. Medicine (Baltimore) 2020; 99(28): e20792.
[http://dx.doi.org/10.1097/MD.0000000000020792] [PMID: 32664071]
[81]
Ren Y, Chen Z, Wang R, Yu Y, Li D, He Y. Electroacupuncture improves myocardial ischemia injury via activation of adenosine receptors. Purinergic Signal 2020; 16(3): 337-45.
[http://dx.doi.org/10.1007/s11302-020-09704-3] [PMID: 32632520]
[82]
Sun N, Zhou YF, Zhou J, et al. The cerebral mechanism underlying the acupoints with specific effect for gallbladder stone disease: Protocol for a randomized controlled task-fMRI trial. Trials 2021; 22(1): 399.
[http://dx.doi.org/10.1186/s13063-021-05356-9] [PMID: 34127059]
[83]
Zhao J, Yu Y, Luo M, Li L, Rong P. Bi-directional regulation of acupuncture on extrahepatic biliary system: An approach in guinea pigs. Sci Rep 2017; 7(1): 14066.
[http://dx.doi.org/10.1038/s41598-017-14482-x] [PMID: 29070912]
[84]
Chen W, Yu H. Observation on immediate effect of Acupuncture at Yanglingquan Point in relieving biliary colic. Acupuncture Research 2000; (01): 62-3.
[85]
Jiang H, Zhao C, Tang X, et al. Clinical observation on the treatment of acute cholecystitis and biliary colic by needling yanglingquan and gallbladder point. J Hepat Pancreat Surgery 2016; 481-483+488.

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy