Login Register Cart 0
Generic placeholder image

Current Women`s Health Reviews

Editor-in-Chief

ISSN (Print): 1573-4048
ISSN (Online): 1875-6581

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

The Impact of Hookah Smoking on AMH Levels in Women: A Pilot Study

Author(s): Soha Nafez Albeitawi*, Rawan Ahmad Obeidat, Lama Munther Al-Mehaisen, Qasem Jamil Shehab, Garavaglia Elisabetta and Almu’atasim Khamees

Volume 20, Issue 1, 2024

Published on: 09 March, 2023

Article ID: e010223213318 Pages: 7

DOI: 10.2174/1573404819666230201085749

Price: $65

Abstract

Purpose: Hookah (water pipe) smoking, an ancient tobacco smoking method, is gaining widespread popularity worldwide. Although research in this field is still lacking, its harmful effect on human health through the increased risk of cardiovascular disease, infection, and cancer has been proven. Cigarette smoking has been found to have a detrimental effect on reproductive function. However, data about the effect of hookah smoking on human fertility or reproductive outcomes are scarce. In this study, we aimed to determine if smoking hookah has a harmful effect on the human ovarian reserve test, anti-Mullerian hormone levels, and cycle regularity.

Materials and Methods: A total of 100 healthy non-cigarette smoking women in the 25-35 age range undergoing laboratory investigations were randomly chosen to participate. After obtaining consent, they completed a questionnaire about smoking habits and menstrual data. Blood samples were withdrawn for anti-Mullerian hormone testing. The anti-Mullerian hormone levels of 50 women hookahonly smokers were compared to 50 non-smoking women.

Results: There were no significant differences in mean anti-Mullerian hormone levels and cycle regularity between hookah smokers and non-smokers. However, period pain was significantly associated with hookah smokers relative to non-smokers (p = 0.036). There was an inverse relationship between log10 anti-Mullerian hormone levels and log10 hookah smoking index. This correlation was significant as measured by Spearman’s rho test, and the correlation coefficient was -0.331 and p-value = 0.02. Moreover, binary logistic regression for cycle regularity showed that hookah smoking was associated with an increase in the likelihood of having an irregular cycle, but the effect was not significant (p = 0.514) for hookah smoking.

Conclusion: Under the conditions of this study, no significant association between hookah smoking and neither AMH levels nor cycle regularity could be observed.

[1]
Kadhum, M.; Sweidan, A.; Jaffery, A.E.; Al-Saadi, A.; Madden, B. A review of the health effects of smoking shisha. Clin. Med., 2015, 15(3), 263-266.
[http://dx.doi.org/10.7861/clinmedicine.15-3-263] [PMID: 26031977]
[2]
Bou Fakhreddine, H.M.; Kanj, A.N.; Kanj, N.A. The growing epidemic of water pipe smoking: Health effects and future needs. Respir. Med., 2014, 108(9), 1241-1253.
[http://dx.doi.org/10.1016/j.rmed.2014.07.014] [PMID: 25130679]
[3]
El-Zaatari, Z.M.; Chami, H.A.; Zaatari, G.S. Health effects associated with waterpipe smoking. Tob. Control, 2015, 24(S1), i31-i43.
[http://dx.doi.org/10.1136/tobaccocontrol-2014-051908] [PMID: 25661414]
[4]
Waziry, R.; Jawad, M.; Ballout, R.A.; Al Akel, M.; Akl, E.A. The effects of waterpipe tobacco smoking on health outcomes: an updated systematic review and meta-analysis. Int. J. Epidemiol., 2017, 46(1), 32-43.
[PMID: 27075769]
[5]
Hannoun, A.; Nassar, A.H.; Usta, I.M.; Musa, A.A. Effect of female nargile smoking on in vitro fertilization outcome. Eur. J. Obstet. Gynecol. Reprod. Biol., 2010, 150(2), 171-174.
[http://dx.doi.org/10.1016/j.ejogrb.2010.02.036] [PMID: 20223580]
[6]
Freour, T.; Masson, D.; Mirallie, S.; Jean, M.; Bach, K.; Dejoie, T.; Barriere, P. Active smoking compromises IVF outcome and affects ovarian reserve. Reprod. Biomed. Online, 2008, 16(1), 96-102.
[http://dx.doi.org/10.1016/S1472-6483(10)60561-5] [PMID: 18252054]
[7]
Fuentes, A.; Escalona, J.; Céspedes, P.; Repetto, V.; Iñiguez, G. Effects of smoking on plasma antimüllerian hormone concentrations among infertile women. Rev. Med. Chil., 2013, 141(1), 23-27.
[http://dx.doi.org/10.4067/S0034-98872013000100003] [PMID: 23732410]
[8]
Waylen, A.L.; Jones, G.L.; Ledger, W.L. Effect of cigarette smoking upon reproductive hormones in women of reproductive age: a retrospective analysis. Reprod. Biomed. Online, 2010, 20(6), 861-865.
[http://dx.doi.org/10.1016/j.rbmo.2010.02.021] [PMID: 20378408]
[9]
Kline, J.; Tang, A.; Levin, B. Smoking, alcohol and caffeine in relation to two hormonal indicators of ovarian age during the reproductive years. Maturitas, 2016, 92, 115-122.
[http://dx.doi.org/10.1016/j.maturitas.2016.07.010] [PMID: 27621248]
[10]
Hawkins Bressler, L.; Bernardi, L.A.; De Chavez, P.J.D.; Baird, D.D.; Carnethon, M.R.; Marsh, E.E. Alcohol, cigarette smoking, and ovarian reserve in reproductive-age African-American women. Am. J. Obstet. Gynecol., 2016, 215(6), 758.e1-758.e9.
[http://dx.doi.org/10.1016/j.ajog.2016.07.012] [PMID: 27418446]
[11]
Dewailly, D.; Andersen, C.Y.; Balen, A.; Broekmans, F.; Dilaver, N.; Fanchin, R.; Griesinger, G.; Kelsey, T.W.; La Marca, A.; Lambalk, C.; Mason, H.; Nelson, S.M.; Visser, J.A.; Wallace, W.H.; Anderson, R.A. The physiology and clinical utility of anti-Müllerian hormone in women. Hum. Reprod. Update, 2014, 20(3), 370-385.
[http://dx.doi.org/10.1093/humupd/dmt062] [PMID: 24430863]
[12]
Broer, S.L.; Broekmans, F.J.M.; Laven, J.S.E.; Fauser, B.C.J.M. Anti-Müllerian hormone: ovarian reserve testing and its potential clinical implications. Hum. Reprod. Update, 2014, 20(5), 688-701.
[http://dx.doi.org/10.1093/humupd/dmu020] [PMID: 24821925]
[13]
Neergaard, J.; Singh, P.; Job, J.; Montgomery, S. Waterpipe smoking and nicotine exposure: A review of the current evidence. Nicotine Tob. Res., 2007, 9(10), 987-994.
[http://dx.doi.org/10.1080/14622200701591591] [PMID: 17943617]
[14]
Barnett, T.E.; Lorenzo, F.E.; Soule, E.K. Hookah smoking outcome expectations among young adults. Subst. Use Misuse, 2017, 52(1), 63-70.
[http://dx.doi.org/10.1080/10826084.2016.1214152] [PMID: 27668728]
[15]
Penzias, A.; Bendikson, K.; Butts, S.; Coutifaris, C.; Falcone, T.; Gitlin, S.; Gracia, C.; Hansen, K.; Jindal, S.; Kalra, S.; Mersereau, J.; Odem, R.; Paulson, R.; Pfeifer, S.; Pisarska, M.; Rebar, R.; Reindollar, R.; Rosen, M.; Sandlow, J.; Schlegel, P.; Stovall, D.; Vernon, M. Smoking and infertility: a committee opinion. Fertil. Steril., 2018, 110(4), 611-618.
[http://dx.doi.org/10.1016/j.fertnstert.2018.06.016] [PMID: 30196946]
[16]
Firns, S.; Cruzat, V.F.; Keane, K.N.; Joesbury, K.A.; Lee, A.H.; Newsholme, P.; Yovich, J.L. The effect of cigarette smoking, alcohol consumption and fruit and vegetable consumption on IVF outcomes: a review and presentation of original data. Reprod. Biol. Endocrinol., 2015, 13(1), 134.
[http://dx.doi.org/10.1186/s12958-015-0133-x] [PMID: 26669322]
[17]
Jordan Population and Family Health Survey 2017-18 – Department of Statistics. Available from: http://dosweb.dos.gov.jo/ products/dhs2017-2018/
[18]
STATcompiler. Available from: https://www.statcompiler.com/en/index.html
[19]
Abu-Helalah, M.A.; Alshraideh, H.A.; Al-Serhan, A.A.A.; Nesheiwat, A.I.; Da’na, M.; Al-Nawafleh, A. Epidemiology, attitudes and perceptions toward cigarettes and hookah smoking amongst adults in Jordan. Environ. Health Prev. Med., 2015, 20(6), 422-433.
[http://dx.doi.org/10.1007/s12199-015-0483-1] [PMID: 26194452]
[20]
Nagata, N.; Niikura, R.; Shimbo, T.; Kishida, Y.; Sekine, K.; Tanaka, S.; Aoki, T.; Watanabe, K.; Akiyama, J.; Yanase, M.; Itoh, T.; Mizokami, M.; Uemura, N. Alcohol and smoking affect risk of uncomplicated colonic diverticulosis in Japan. PLoS One, 2013, 8(12), e81137.
[http://dx.doi.org/10.1371/journal.pone.0081137] [PMID: 24339905]
[21]
Budani, M.C.; Tiboni, G.M. Ovotoxicity of cigarette smoke: A systematic review of the literature. Reprod. Toxicol., 2017, 72, 164-181.
[http://dx.doi.org/10.1016/j.reprotox.2017.06.184] [PMID: 28684319]
[22]
Plante, B.J.; Cooper, G.S.; Baird, D.D.; Steiner, A.Z. The impact of smoking on antimüllerian hormone levels in women aged 38 to 50 years. Menopause, 2010, 17(3), 571-576.
[http://dx.doi.org/10.1097/gme.0b013e3181c7deba] [PMID: 20065884]
[23]
Oboni, J.B.; Marques-Vidal, P.; Bastardot, F.; Vollenweider, P.; Waeber, G. Impact of smoking on fertility and age of menopause: a population-based assessment. BMJ Open, 2016, 6(11), e012015.
[http://dx.doi.org/10.1136/bmjopen-2016-012015] [PMID: 27864244]
[24]
Qin, L.L.; Hu, Z.; Kaminga, A.C.; Luo, B.A.; Xu, H.L.; Feng, X.L.; Liu, J.H. Association between cigarette smoking and the risk of dysmenorrhea: A meta-analysis of observational studies. PLoS One, 2020, 15(4), e0231201.
[http://dx.doi.org/10.1371/journal.pone.0231201] [PMID: 32294123]
[25]
Fritz, M.A.; Speroff, L. Clinical gynecologic endocrinology and infertility; Lippincott Williams & Wilkins, 2011.
[26]
Hornsby, P.P.; Wilcox, A.J.; Weinberg, C.R. Cigarette smoking and disturbance of menstrual function. Epidemiology, 1998, 9(2), 193-198.
[http://dx.doi.org/10.1097/00001648-199803000-00016] [PMID: 9504290]

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy