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Applied Drug Research, Clinical Trials and Regulatory Affairs

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ISSN (Print): 2667-3371
ISSN (Online): 2667-338X

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Review Article

Novel Approaches of Self Emulsifying Drug Delivery Systems and Recent Patents: A Comprehensive Review

Author(s): Rimmy Nandal, Sumit Tahlan and Aakash Deep*

Volume 9, Issue 1, 2022

Published on: 03 February, 2023

Article ID: e200123212928 Pages: 16

DOI: 10.2174/2667337109666230120095944

Price: $65

Abstract

The main aim of the current work is to set up a revolutionary Self Nano-emulsifying drug delivery system to improve the necessary bio-availability and to boost clinical efficacy when administered orally. This study's main target is to develop a novel self-nano emulsifying drug delivery system (SNEDDS) for orally administered, poorly water-soluble medicines. SNEDDS is designed to intensify weakly water dissolvable or lipophilic drugs. SNEDDS is designed to intensify weakly water dissolvable or lipophilic drugs. It contains a micro- or nano-emulsion of oil carrying medicament that spontaneously agitates an aqueous medium. For enhancing the solubility of lipophilic medicines, SNEDDS is the most significantly used in biopharmaceutics classification system [BCS class] II and IV pharmaceuticals. The improved rate of dissolution and prevention of interfacial tension are clearly demonstrated by SNEDDS. In aqueous mediums, such as gastrointestinal fluid, SNEDDS produces a stable emulsion after dilution.

Graphical Abstract

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