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CNS & Neurological Disorders - Drug Targets

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ISSN (Print): 1871-5273
ISSN (Online): 1996-3181

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Research Article

Ameliorating Effects of Virgin Coconut Oil (VCO) on Nicotine Dependence and Quality of Life in Smokers

Author(s): Kusnandar Anggadiredja*, Lia Amalia and Fahmy Ahsanul Haq

Volume 22, Issue 8, 2023

Published on: 13 January, 2023

Page: [1243 - 1249] Pages: 7

DOI: 10.2174/1871527322666221128141647

open access plus

Abstract

Background: Safer and effective alternatives to manage nicotine dependence are still required. Preliminary studies have shown the potential of virgin coconut oil (VCO) to be used in dependence treatment.

Objective: To assess the VCO effect administered for 14 days on nicotine dependence and quality of life.

Methods: Forty smoking subjects participated in an open-label, single-center, pre/post-intervention study, and were required to take 15 ml VCO twice daily for 14 days. They were evaluated with the Fagerstrom Test for Nicotine Dependence (FTND) for nicotine dependence intensity and EuroQolvisual analogue scales (EQ VAS) for quality of life.

Results: The VCO regimen improved FTND (0.53 points decrease, p<0.05) and EQ-VAS (5.85 points increase p<0.01) scores. Adverse events were all mild.

Conclusion: Results of the present study suggest that VCO has the potential to be a safe and effective adjunct therapy for the management of nicotine dependence.

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