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Pharmaceutical Nanotechnology

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ISSN (Print): 2211-7385
ISSN (Online): 2211-7393

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Review Article

Interpenetrating Polymer Networks of Polyacrylamide with Polyacrylic and Polymethacrylic Acids and Their Application for Modified Drug Delivery - a Flash Review

Author(s): Marin Simeonov*, Bistra Kostova and Elena Vassileva

Volume 11, Issue 1, 2023

Published on: 19 October, 2022

Page: [25 - 33] Pages: 9

DOI: 10.2174/2211738510666220919103514

Price: $65

Abstract

Polyacrylic and polymethacrylic acids, in combination with polymers such as polyacrylamide, provide the ability for controlled and sustained drug delivery since they represent pHand temperature responsiveness. In addition, the synthesis techniques can be used to develop a higher level of supramolecular structures as the interpenetrating polymer networks - as bulk hydrogels or micro-/nanogels. They can provide the opportunity to organize and build up state-ofthe- art carriers for different types of drugs, thus providing the ability to control their loading capacity and drug release performance. This flash review aims to summarize the efforts for synthesizing such interpenetrating polymer networks and their properties and to demonstrate the authors' contributions to this field.

Keywords: Interpenetrating polymer networks, hydrogel, microgel, drug delivery, poly(acrylic acid), poly(methacrylic acid), polyacrylamide

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