Abstract
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide. There is no effective medication for COVID- 19 as of now, so it would be good to take preventive measures that not only boost our immunity but also fight against infections. The use of traditional Chinese medicine in China to treat COVID-19 patients sets the prototype demonstrating that traditional medicines can contribute to prevention and treatment successfully. In India, the Ministry of AYUSH (Ayurveda, Yoga, Unani, Siddha, Homeopathy) released a self-care advisory during the COVID-19 crisis as a preventive aspect. This review article discusses the therapeutic potential and clinical relevance of some herbs [(Tulsi (Ocimum sanctum), Haridra (Curcuma longa), Tvaka (Cinnamon), Maricha (Piper longum), Shunthi (Zingiber officinale), Munakka (Dried grapes), Lavang (Syzigiumaromaticum), Pudina (Mentha arvensis), and Ajwain (Trachyspermum ammi)] advised by AUYSH to take during COVID-19 infection. They are effective in COVID-19 management, therefore, authors have discussed their detailed traditional uses as therapeutics and spotted scientific insight and clinical significance of the herbs mentioned above along with their mechanistic viewpoint, adequately, on a single platform. Provided information could be a treasure to open up a new research arena on natural products to manage human health crises effectively, caused not only by COVID-19 but also by other infectious diseases.
Keywords: Ayurvedic herbs, Traditional use, COVID-19, Prevention, Therapeutic potential, Clinical relevance.
[http://dx.doi.org/10.1007/s11655-021-3331-8] [PMID: 33544289]
[http://dx.doi.org/10.1016/S0378-8741(01)00373-7] [PMID: 11891082]
[http://dx.doi.org/10.1016/S1995-7645(10)60021-1]
[PMID: 19597641]
[http://dx.doi.org/10.1016/j.jep.2011.05.012] [PMID: 21619917]
[http://dx.doi.org/10.4103/0253-7613.70108] [PMID: 21206619]
[PMID: 19253862]
[http://dx.doi.org/10.3390/molecules23112778] [PMID: 30373170]
[http://dx.doi.org/10.4110/in.2019.19.e35] [PMID: 31720046]
[http://dx.doi.org/10.1089/jmf.2017.4093] [PMID: 29862890]
[http://dx.doi.org/10.1016/j.imr.2018.02.004] [PMID: 29989030]
[http://dx.doi.org/10.1006/jsre.2000.5826] [PMID: 10729246]
[http://dx.doi.org/10.1155/2014/186864] [PMID: 24877064]
[http://dx.doi.org/10.1186/1472-6882-13-275] [PMID: 24148965]
[http://dx.doi.org/10.1016/S0192-0561(98)00064-2] [PMID: 9848396]
[http://dx.doi.org/10.1016/j.jep.2005.01.032] [PMID: 15876501]
[http://dx.doi.org/10.1016/j.antiviral.2009.02.001] [PMID: 19428598]
[http://dx.doi.org/10.3389/fmicb.2015.01368]
[http://dx.doi.org/10.1016/j.ejphar.2007.07.033] [PMID: 17706638]
[http://dx.doi.org/10.1089/mdr.2018.0107] [PMID: 30096263]
[http://dx.doi.org/10.1016/S0378-8741(03)00182-X] [PMID: 12902058]
[http://dx.doi.org/10.1016/S0378-8741(99)00181-6] [PMID: 10904150]
[http://dx.doi.org/10.1211/jpp/61.07.0017] [PMID: 19589240]
[http://dx.doi.org/10.1016/S1995-7645(14)60271-6]
[http://dx.doi.org/10.1016/j.micpath.2017.03.029] [PMID: 28389345]
[http://dx.doi.org/10.1590/0103-6440201300199] [PMID: 25831098]
[http://dx.doi.org/10.5772/59377]
[http://dx.doi.org/10.2174/157488612802715627] [PMID: 22873496]
[http://dx.doi.org/10.1016/j.nutres.2010.07.005] [PMID: 20851304]
[http://dx.doi.org/10.1016/j.phytol.2008.07.007]
[http://dx.doi.org/10.1016/j.fm.2015.05.011] [PMID: 26338111]
[http://dx.doi.org/10.1016/j.phrs.2013.03.011] [PMID: 23557933]
[http://dx.doi.org/10.3390/biom9050161] [PMID: 31035513]
[PMID: 25872246]
[http://dx.doi.org/10.4103/asl.ASL_8_17] [PMID: 28867858]
[http://dx.doi.org/10.1016/S2221-1691(14)60215-X] [PMID: 25182278]
[http://dx.doi.org/10.3109/1547691X.2014.912698] [PMID: 24873744]
[PMID: 9454821]
[http://dx.doi.org/10.1371/journal.pone.0061026] [PMID: 23613775]
[http://dx.doi.org/10.3390/ijms19020355] [PMID: 29370076]
[http://dx.doi.org/10.4103/0973-7847.95871] [PMID: 22654405]
[http://dx.doi.org/10.1002/14651858.CD004882.pub3] [PMID: 23076910]
[http://dx.doi.org/10.1016/j.phrs.2020.104743] [PMID: 32145402]
[http://dx.doi.org/10.3390/molecules22071191]
[http://dx.doi.org/10.1007/s00203-016-1314-5] [PMID: 27830269]
[http://dx.doi.org/10.1016/j.phymed.2011.11.010] [PMID: 22240078]
[http://dx.doi.org/10.1186/s12906-018-2238-1] [PMID: 29866088]
[http://dx.doi.org/10.1088/1755-1315/101/1/012005]
[http://dx.doi.org/10.1016/j.antiviral.2007.01.003] [PMID: 17303260]
[PMID: 11094851]
[http://dx.doi.org/10.4014/jmb.1210.10078] [PMID: 23676919]
[http://dx.doi.org/10.3389/fphar.2016.00490] [PMID: 28066241]
[http://dx.doi.org/10.4315/0362-028X.JFP-15-593] [PMID: 27296605]
[http://dx.doi.org/10.4103/0974-8490.157977] [PMID: 26130938]
[PMID: 11363190]
[http://dx.doi.org/10.1093/jn/136.3.816S] [PMID: 16484572]
[http://dx.doi.org/10.1007/BF02850113] [PMID: 11697022]
[http://dx.doi.org/10.1016/j.clnu.2011.11.019] [PMID: 22280901]
[http://dx.doi.org/10.1007/s11481-021-10028-1] [PMID: 34677731]
[http://dx.doi.org/10.3390/v13101914] [PMID: 34696344]
[http://dx.doi.org/10.3390/biomedicines9101434] [PMID: 34680551]
[http://dx.doi.org/10.1016/j.compbiomed.2021.104818] [PMID: 34481181]
[http://dx.doi.org/10.1007/s13337-020-00598-8] [PMID: 32656311]
[http://dx.doi.org/10.23869/bphjbr.25.2.20207]
[http://dx.doi.org/10.1080/07391102.2020.1810778] [PMID: 32851919]
[http://dx.doi.org/10.33263/BRIAC111.79817993]
[http://dx.doi.org/10.3389/fmolb.2021.637329] [PMID: 34277698]
[http://dx.doi.org/10.5455/jabet.2022.d109]
[http://dx.doi.org/10.22270/jddt.v11i2.4610]
[http://dx.doi.org/10.1016/j.phymed.2021.153494] [PMID: 33596494]
[http://dx.doi.org/10.1016/j.jaim.2021.05.008] [PMID: 34127896]
[http://dx.doi.org/10.1016/j.jaim.2020.10.008] [PMID: 33100779]
[http://dx.doi.org/10.4103/jpbs.jpbs_242_21] [PMID: 34349488]
[http://dx.doi.org/10.1016/j.jaim.2020.12.013]