Login Register Cart 0
Generic placeholder image

Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Case Report

B-Cell Lymphoma Associated with COVID‐19 Infection: A Case Report

Author(s): Lili Yang, Jiawei He, Xiaoji Lin, Dandan Zhao, Xianhui Lin, Zhihan Yan* and Feng Chen*

Volume 18, Issue 11, 2022

Published on: 17 May, 2022

Article ID: e290322202796 Pages: 4

DOI: 10.2174/1573405618666220329210311

Price: $65

Abstract

Purpose: Most common publications are related to COVID-19 diagnosis in hematological malignancy patients. However, here we report a case involving a patient diagnosed with B-cell lymphoma while undergoing treatment for COVID‐19, including the changes in major clinical symptoms and medical examinations, then explain the probable causes of the case.

Case Presentation: A 74-year-old woman with a previous history of oesophageal cancer was admitted to the hospital after having cough and sputum for 15 days. Despite the COVID-19 symptoms, this patient did not have a fever at the time of the onset. Results of routine blood tests were normal at first but then declined with persistent fever, and A whole-body C.T. examination ruled out the possibility of tumor-metastasis–related fever. This patient had no hepatosplenomegaly or regional lymphadenopathy, and there was no concrete evidence of haemophagocytic lymphohistiocytosis or lymphoma until bone marrow biopsy results confirmed the latter.

Conclusion: We describe an uncommon case of COVID-19 who was finally diagnosed with B-cell lymphoma. An awareness of persistent fever and declined routine blood tests caused by hematological malignancies instead of COVID-19 itself can aid in providing appropriate guidelines for management and treatment.

Keywords: COVID-19, SARS-CoV-2, lymphomas, fever, infection, malignancy.

Graphical Abstract

[1]
Chari, A.; Samur, M.K.; Martinez-Lopez, J.; Cook, G.; Biran, N.; Yong, K.; Hungria, V.; Engelhardt, M.; Gay, F.; García Feria, A.; Oliva, S.; Oostvogels, R.; Gozzetti, A.; Rosenbaum, C.; Kumar, S.; Stadtmauer, E.A.; Einsele, H.; Beksac, M.; Weisel, K.; Anderson, K.C.; Mateos, M.V.; Moreau, P.; San-Miguel, J.; Munshi, N.C.; Avet-Loiseau, H. Clinical features associated with COVID-19 outcome in multiple myelo-ma: First results from the International Myeloma Society data set. Blood, 2020, 136(26), 3033-3040.
[http://dx.doi.org/10.1182/blood.2020008150] [PMID: 33367546]
[2]
García-Suárez, J.; de la Cruz, J.; Cedillo, Á.; Llamas, P.; Duarte, R.; Jiménez-Yuste, V.; Hernández-Rivas, J.Á.; Gil-Manso, R.; Kwon, M.; Sánchez-Godoy, P.; Martínez-Barranco, P.; Colás-Lahuerta, B.; Herrera, P.; Benito-Parra, L.; Alegre, A.; Velasco, A.; Matilla, A.; Aláez-Usón, M.C.; Martos-Martínez, R.; Martínez-Chamorro, C.; Susana-Quiroz, K.; Del Campo, J.F.; de la Fuente, A.; Herráez, R.; Pascual, A.; Gómez, E.; Pérez-Oteyza, J.; Ruiz, E.; Alonso, A.; González-Medina, J.; Martín-Buitrago, L.N.; Canales, M.; González-Gascón, I.; Vicente-Ayuso, M.C.; Valenciano, S.; Roa, M.G.; Monteliu, P.E.; López-Jiménez, J.; Escobar, C.E.; Ortiz-Martín, J.; Diez-Martin, J.L.; Martinez-Lopez, J. Impact of hematologic malignancy and type of cancer therapy on COVID-19 severity and mortality: Lessons from a large popula-tion-based registry study. J. Hematol. Oncol., 2020, 13(1), 133.
[http://dx.doi.org/10.1186/s13045-020-00970-7] [PMID: 33032660]
[3]
Opoka-Winiarska, V.; Grywalska, E. Roliński, J. Could hemophagocytic lymphohistiocytosis be the core issue of severe COVID-19 cases? BMC Med., 2020, 18(1), 214.
[http://dx.doi.org/10.1186/s12916-020-01682-y] [PMID: 32664932]
[4]
Li, Q.; Zhu, F.; Xiao, Y.; Liu, T.; Liu, X.; Wu, G.; Zhang, L. A primary mediastinal large B-cell lymphoma patient with COVID-19 infection after intensive immunochemotherapy: A case report. Front. Oncol., 2020, 10, 924.
[http://dx.doi.org/10.3389/fonc.2020.00924] [PMID: 32574278]
[5]
Yilmaz, F.; Yasar, S.; Tuncali, M.C.; Akin, S. Complete response in a frail patient with high-grade B-cell lymphoma to only one cycle of R-CHOP or to prolonged COVID-19? Semin. Oncol., 2021, 48(4-6), 279-282.
[http://dx.doi.org/10.1053/j.seminoncol.2021.11.001] [PMID: 34895738]
[6]
Lazarian, G.; Quinquenel, A.; Bellal, M.; Siavellis, J.; Jacquy, C.; Re, D.; Merabet, F.; Mekinian, A.; Braun, T.; Damaj, G.; Delmer, A.; Cym-balista, F. Autoimmune haemolytic anaemia associated with COVID-19 infection. Br. J. Haematol., 2020, 190(1), 29-31.
[http://dx.doi.org/10.1111/bjh.16794] [PMID: 32374906]
[7]
Zulfiqar, A.A.; Lorenzo-Villalba, N.; Hassler, P.; Andrès, E. Immune thrombocytopenic purpura in a patient with Covid-19. N. Engl. J. Med., 2020, 382(18), e43.
[http://dx.doi.org/10.1056/NEJMc2010472] [PMID: 32294340]

Rights & Permissions Print Cite
Article Metrics
16
1
© 2024 Bentham Science Publishers | Privacy Policy