Abstract
In view of the crucial importance of the bioactivities of N-acylhydrazone derivatives and their corresponding metal complexes, N-acylhydrazones have recently attracted the attention of researchers in the chemical, biological, and pharmaceutical fields. This review aims to describe Nacylhydrazone complexes involving transition metal ions, such as copper, chromium, manganese, iron, cobalt, nickel, and zinc, and investigate their properties and possible applications in various domains. The most promising applications of the number of transition metal complexes incorporating Nacylhydrazones in biology, medicine, and pharmacology are also examined and determined.
Keywords: N-Acylhydrazone, transition metal complexes, Schiff-base, bio-inorganic chemistry, bioactive molecules, antitumor.
Graphical Abstract
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