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Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Case Report

An Unusual Complication of Transarterial Chemoembolization of Hepatocellular Carcinoma; Pseudoaneurysm: A Case Report

Author(s): Musa Atay* and Huseyin Ozdemir

Volume 18, Issue 11, 2022

Published on: 10 June, 2022

Article ID: e250322202620 Pages: 4

DOI: 10.2174/1573405618666220325101911

Price: $65

Abstract

Background: Transarterial chemoembolization (TACE) is a globally recognised treatment method for hepatic tumors, especially unresectable hepatocellular carcinoma (HCC). Although the technique is relatively safe, it may cause serious complications, such as liver abscess, liver failure, and non-target embolization. Here, the case of a rare complication of TACE is presented.

Case Presentation: A-55-year-old male patient was referred to the interventional radiology department for surgically unresectable HCC. CT scan showed a heterogeneously enhancing lesion with capsular enhancement consistent with HCC. On MRI examination, a central necrotic part was seen within the lesion, and TACE was performed. At the end of the TACE, a pseudoaneurysm of the hepatic artery was detected, which was successfully embolized with pushable micro-coils.

Conclusion: To the best of our knowledge, very few cases of pseudoaneurysm of the hepatic artery have been described in the literature, and in those cases, the cause has been thought to be guidewire manipulation. In contrast, in the current case, it was thought that it might occur due to central necrosis and central perfusion insufficiency of the lesion. Pseudoaneurysm is a treatable condition with coil embolization.

Keywords: Transarterial chemoembolization, hepatocellular carcinoma, pseudoaneurysm, hepatic artery, embolization, MRI.

Graphical Abstract

[1]
Yamashita Y, Takahashi M, Koga Y, et al. Prognostic factors in the treatment of hepatocellular carcinoma with transcatheter arterial emboli-zation and arterial infusion. Cancer 1991; 67(2): 385-91.
[http://dx.doi.org/10.1002/1097-0142(19910115)67:2<385::AID-CNCR2820670212>3.0.CO;2-Q] [PMID: 1845943]
[2]
Shin SW. The current practice of transarterial chemoembolization for the treatment of hepatocellular carcinoma. Korean J Radiol 2009; 10(5): 425-34.
[http://dx.doi.org/10.3348/kjr.2009.10.5.425] [PMID: 19721826]
[3]
Cun J, Xu Y, Li W, Zhao X. Analysis of factors affecting the prognosis of transcatheter arterial chemoembolization for hepatitis B-related hepatocellular carcinoma. J Interv Med 2021; 4(2): 66-70.
[http://dx.doi.org/10.1016/j.jimed.2021.02.008] [PMID: 34805950]
[4]
Poggi G, Pozzi E, Riccardi A, et al. Complications of image-guided transcatheter hepatic chemoembolization of primary and secondary tu-mours of the liver. Anticancer Res 2010; 30(12): 5159-64.
[PMID: 21187505]
[5]
Cammà C, Schepis F, Orlando A, et al. Transarterial chemoembolization for unresectable hepatocellular carcinoma: Meta-analysis of ran-domized controlled trials. Radiology 2002; 224(1): 47-54.
[http://dx.doi.org/10.1148/radiol.2241011262] [PMID: 12091661]
[6]
Lee HS, Kim JS, Choi IJ, Chung JW, Park JH, Kim CY. The safety and efficacy of transcatheter arterial chemoembolization in the treatment of patients with hepatocellular carcinoma and main portal vein obstruction. A prospective controlled study. Cancer 1997; 79(11): 2087-94.
[http://dx.doi.org/10.1002/(SICI)1097-0142(19970601)79:11<2087::AID-CNCR5>3.0.CO;2-M] [PMID: 9179054]
[7]
Pentecost MJ, Daniels JR, Teitelbaum GP, Stanley P. Hepatic chemoembolization: Safety with portal vein thrombosis. J Vasc Interv Radiol 1993; 4(3): 347-51.
[http://dx.doi.org/10.1016/S1051-0443(93)71873-4] [PMID: 8513208]
[8]
Maeda N, Osuga K, Mikami K, et al. Angiographic evaluation of hepatic arterial damage after transarterial chemoembolization for hepatocel-lular carcinoma. Radiat Med 2008; 26(4): 206-12.
[http://dx.doi.org/10.1007/s11604-007-0216-5] [PMID: 18509720]
[9]
Sueyoshi E, Hayashida T, Sakamoto I, Uetani M. Vascular complications of hepatic artery after transcatheter arterial chemoembolization in patients with hepatocellular carcinoma. AJR Am J Roentgenol 2010; 195(1): 245-51.
[http://dx.doi.org/10.2214/AJR.08.2301] [PMID: 20566824]
[10]
Sakamoto I, Aso N, Nagaoki K, et al. Complications associated with transcatheter arterial embolization for hepatic tumors. Radiographics 1998; 18(3): 605-19.
[http://dx.doi.org/10.1148/radiographics.18.3.9599386] [PMID: 9599386]

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