摘要
慢性阻塞性肺疾病(COPD)是一种以肺气肿导致肺泡狭窄为特征的疾病。因此,目前还没有完全治愈这种疾病的治疗方法,现有的药物只能延缓疾病的进展。近年来,干细胞分泌组作为一种药物被广泛应用于再生治疗。特别是,无细胞治疗方法为COPD的治疗提供了很大的机会。然而,一些问题,如干细胞分泌组药物输送到肺泡区域,阻碍了其在临床规模的应用。为了应对这些挑战,将干细胞分泌组作为一种药物与纳米技术相结合可能是一个明智的解决方案。我们认为,联合递送载干细胞分泌组的纳米颗粒的方法可能是一种成功治疗COPD的转化医学方法。
关键词: 纳米颗粒,间充质干细胞,分泌组,再生医学,慢性阻塞性肺疾病,药物输送。
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