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Infectious Disorders - Drug Targets

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ISSN (Print): 1871-5265
ISSN (Online): 2212-3989

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Case Report

Does Methylene Blue Satisfy an Option in COVID-19 ARDS

Author(s): Sri Hari Tanguturi Yella, Sree Sudha Tanguturi Yella*, Kota Sesha Brahma Shree Krishna Sasanka and Pugazhenthan Thangaraju

Volume 22, Issue 6, 2022

Published on: 23 May, 2022

Article ID: e170322202339 Pages: 4

DOI: 10.2174/1871526522666220317155947

Price: $65

Abstract

Background: In COVID-19, the respiratory tract is usually affected by SARS-CoV-2 infection. Due to viral transmission in the blood and an overwhelming inflammatory response, including cytokine storm, the condition can progress to acute respiratory distress syndrome and failure. Methylene blue is the only medicine that has been shown to reduce the excessive generation of reactive species and cytokines.

Case Presentation: A 51-year-old male patient came to the hospital with shortness of breath. At room air, the patient was having 70% Spo2. The patient was treated with a noninvasive ventilator (NIV) and Standard of care (SOC). Due to prolonged hypoxia and respiratory distress, the patient was treated with NIV and the methylene blue (MB) was given in a humidifier for 5 days.

Result: Methylene blue resulted in a significant decrease in respiratory distress and a steep rise in Spo2.

Conclusion: We suggest trying methylene blue as an additional intervention in COVID-related acute respiratory distress to avoid the disease's devastating consequences.

Keywords: COVID-19, methylene blue, acute respiratory distress, non-invasive ventilator, the standard of care, Spo2.

Graphical Abstract

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