Abstract
Lipid metabolism disorder is a multifactor issue, which contributes to several serious health consequences, such as obesity, hyperlipidemia, atherosclerosis diabetes, non-alcoholic fatty liver, etc. Tannins, applied as naturally derived plants, are commonly used in the study of lipid metabolism disease with excellent safety and effectiveness while producing less toxic and side effects. Meanwhile, recognition of the significance of dietary tannins in lipid metabolism disease prevention has increased. As suggested by existing evidence, dietary tannins can reduce lipid accumulation, block adipocyte differentiation, enhance antioxidant capacity, increase the content of short-chain fatty acids, and lower blood lipid levels, thus alleviating lipid metabolism disorder. This study is purposed to sum up and analyze plenty of documents on tannins, so as to provide the information required to assess the lipid metabolism of tannins.
Keywords: Tannins, lipid metabolism, obesity, hyperlipidemia, diabetes, non-alcoholic fatty liver.
Graphical Abstract
[http://dx.doi.org/10.1038/nature08532] [PMID: 19924209]
[http://dx.doi.org/10.1111/j.1467-789X.2006.00230.x] [PMID: 16866975]
[http://dx.doi.org/10.1038/nrendo.2011.183] [PMID: 22064493]
[http://dx.doi.org/10.3390/molecules26020337] [PMID: 33440779]
[http://dx.doi.org/10.1016/j.abb.2016.02.017] [PMID: 26891591]
[http://dx.doi.org/10.2174/1871530318666181029160539] [PMID: 30370866]
[http://dx.doi.org/10.5650/jos.ess18226] [PMID: 30971641]
[http://dx.doi.org/10.1002/mnfr.201900082] [PMID: 30893514]
[http://dx.doi.org/10.1002/cbdv.200490036] [PMID: 17191857]
[http://dx.doi.org/10.1038/s41598-019-55779-3] [PMID: 31844118]
[http://dx.doi.org/10.3390/molecules201219878] [PMID: 26703543]
[http://dx.doi.org/10.1016/j.freeradbiomed.2019.03.011] [PMID: 30878647]
[http://dx.doi.org/10.1002/mnfr.201900574] [PMID: 31444955]
[http://dx.doi.org/10.1016/j.foodchem.2012.06.034] [PMID: 22953907]
[http://dx.doi.org/10.1016/j.ejphar.2011.12.034] [PMID: 22227333]
[http://dx.doi.org/10.1016/j.jnutbio.2013.08.001] [PMID: 24231101]
[http://dx.doi.org/10.1002/mnfr.201801413] [PMID: 31018035]
[http://dx.doi.org/10.3746/pnf.2020.25.3.254] [PMID: 33083374]
[http://dx.doi.org/10.1155/2015/948262] [PMID: 25785232]
[http://dx.doi.org/10.1016/j.biopha.2017.10.139] [PMID: 29793326]
[http://dx.doi.org/10.1016/j.jep.2013.04.053] [PMID: 23685195]
[http://dx.doi.org/10.1021/acs.jafc.5b01082] [PMID: 26207852]
[http://dx.doi.org/10.7717/peerj.8165] [PMID: 31803542]
[http://dx.doi.org/10.3390/ijms21062029] [PMID: 32188147]
[http://dx.doi.org/10.1016/j.phytochem.2011.12.008] [PMID: 22277734]
[http://dx.doi.org/10.3390/nu10050593] [PMID: 29748512]
[http://dx.doi.org/10.1194/jlr.M400209-JLR200] [PMID: 15576849]
[http://dx.doi.org/10.1021/acs.jafc.9b05495] [PMID: 31608624]
[http://dx.doi.org/10.1111/jfbc.13208] [PMID: 32189358]
[http://dx.doi.org/10.3390/molecules25030567] [PMID: 32012956]
[http://dx.doi.org/10.1016/j.cbi.2008.04.016] [PMID: 18534569]
[http://dx.doi.org/10.1007/s00394-014-0814-9] [PMID: 25510894]
[http://dx.doi.org/10.1016/j.cbi.2019.01.037] [PMID: 30721698]
[http://dx.doi.org/10.1186/s12906-018-2244-3] [PMID: 29884167]
[http://dx.doi.org/10.1080/09637486.2020.1754348] [PMID: 32319838]
[http://dx.doi.org/10.1016/j.nut.2020.110973] [PMID: 32916379]
[http://dx.doi.org/10.1021/acs.jafc.9b06167] [PMID: 31789033]
[http://dx.doi.org/10.3748/wjg.v12.i2.214] [PMID: 16482620]
[http://dx.doi.org/10.1021/jf5031554] [PMID: 25185991]
[http://dx.doi.org/10.1002/mnfr.201800129] [PMID: 29797702]
[http://dx.doi.org/10.1016/j.dsx.2019.03.021] [PMID: 31336539]
[http://dx.doi.org/10.1002/cbf.3247] [PMID: 28083965]
[PMID: 21780550]
[http://dx.doi.org/10.1093/jn/132.7.1819] [PMID: 12097653]
[http://dx.doi.org/10.1007/s10552-018-1002-7] [PMID: 29350310]
[http://dx.doi.org/10.1158/0008-5472.CAN-07-0295] [PMID: 17575168]
[http://dx.doi.org/10.1016/j.jnutbio.2005.01.006] [PMID: 15936648]
[http://dx.doi.org/10.1023/A:1014405730585] [PMID: 12002340]
[http://dx.doi.org/10.1016/S1043-6618(03)00041-0] [PMID: 12741998]
[http://dx.doi.org/10.1111/j.1753-4887.2006.tb00194.x] [PMID: 16572598]
[http://dx.doi.org/10.1186/s12906-017-1555-0] [PMID: 28088220]
[http://dx.doi.org/10.1038/s41598-019-51614-x] [PMID: 31636354]
[http://dx.doi.org/10.1186/s12974-018-1182-9] [PMID: 29929563]
[http://dx.doi.org/10.3390/molecules22111989] [PMID: 29149072]
[http://dx.doi.org/10.1038/srep19710] [PMID: 26818408]
[http://dx.doi.org/10.1016/j.physbeh.2007.11.049] [PMID: 18222498]
[http://dx.doi.org/10.1016/j.bbalip.2013.04.003] [PMID: 24046866]
[http://dx.doi.org/10.3389/fnut.2019.00183] [PMID: 31921876]
[http://dx.doi.org/10.1016/j.freeradbiomed.2018.08.024] [PMID: 30142454]
[http://dx.doi.org/10.1101/gad.17420111] [PMID: 21937710]
[http://dx.doi.org/10.3892/mmr.2017.6900] [PMID: 28677803]
[http://dx.doi.org/10.1039/C3FO60635J] [PMID: 24841999]
[http://dx.doi.org/10.1021/acs.jafc.9b01469] [PMID: 30945544]
[http://dx.doi.org/10.1038/nature07976] [PMID: 19339967]
[http://dx.doi.org/10.1002/mnfr.201801255] [PMID: 31336037]
[http://dx.doi.org/10.1016/j.molmet.2018.11.001] [PMID: 30473486]
[http://dx.doi.org/10.1271/bbb.130048] [PMID: 23832332]
[http://dx.doi.org/10.7717/peerj.8165] [PMID: 31803542]
[http://dx.doi.org/10.1039/C9FO00334G] [PMID: 31073569]
[http://dx.doi.org/10.1038/nrm3198] [PMID: 21952300]
[http://dx.doi.org/10.1039/C4FO00871E] [PMID: 25623997]
[http://dx.doi.org/10.1038/s41598-020-57932-9] [PMID: 31969643]
[http://dx.doi.org/10.3390/ijms18010141] [PMID: 28085116]
[http://dx.doi.org/10.1016/j.jep.2018.03.029] [PMID: 29604377]
[http://dx.doi.org/10.1007/s11010-017-3149-z] [PMID: 28819881]
[http://dx.doi.org/10.1080/10495398.2020.1822370] [PMID: 32945731]
[http://dx.doi.org/10.1002/mnfr.201800937] [PMID: 30908878]
[http://dx.doi.org/10.1271/bbb.68.2239] [PMID: 15564660]
[http://dx.doi.org/10.1016/j.foodres.2019.03.014] [PMID: 31000255]
[http://dx.doi.org/10.1136/gutjnl-2014-307142] [PMID: 25080446]
[http://dx.doi.org/10.1093/jn/nxz102] [PMID: 31175811]
[http://dx.doi.org/10.1016/j.jnutbio.2015.03.003] [PMID: 26007288]
[http://dx.doi.org/10.1038/s41598-017-12597-9] [PMID: 28974704]
[http://dx.doi.org/10.1111/and.12632] [PMID: 27362617]
[http://dx.doi.org/10.1016/j.foodchem.2015.01.056] [PMID: 25704681]
[http://dx.doi.org/10.3177/jnsv.61.90] [PMID: 25994144]
[http://dx.doi.org/10.1017/S000711451100256X] [PMID: 21736774]
[PMID: 27624175]
[http://dx.doi.org/10.1017/S0007114511005472] [PMID: 22011563]
[http://dx.doi.org/10.1007/s10695-020-00819-3] [PMID: 32447624]
[http://dx.doi.org/10.1096/fj.04-3095fje] [PMID: 15637110]
[http://dx.doi.org/10.1002/mnfr.200800054] [PMID: 18720348]
[http://dx.doi.org/10.1016/j.cmet.2013.06.010] [PMID: 23823476]
[http://dx.doi.org/10.1002/ptr.6318] [PMID: 30848548]
[http://dx.doi.org/10.1016/j.cbi.2014.05.011] [PMID: 24877639]
[http://dx.doi.org/10.1002/mnfr.201200237] [PMID: 22965541]
[http://dx.doi.org/10.1002/jsfa.9974] [PMID: 31386202]
[http://dx.doi.org/10.1021/acs.jafc.9b03985] [PMID: 31379164]
[http://dx.doi.org/10.1097/01.smj.0000208120.73327.db] [PMID: 16553100]
[http://dx.doi.org/10.3177/jnsv.60.340] [PMID: 25744423]
[http://dx.doi.org/10.2174/1381612054865064] [PMID: 16178764]
[http://dx.doi.org/10.1021/jf803450a] [PMID: 19292475]
[http://dx.doi.org/10.1093/jn/131.8.2082] [PMID: 11481398]
[http://dx.doi.org/10.2174/1389203720666190827143218] [PMID: 31453783]
[http://dx.doi.org/10.1039/C9FO02352F] [PMID: 31967154]
[http://dx.doi.org/10.1097/01.fjc.0000242052.60502.21] [PMID: 16954822]
[http://dx.doi.org/10.1152/ajpendo.00560.2019] [PMID: 32228321]
[http://dx.doi.org/10.1093/ajcn/71.5.1062] [PMID: 10799367]
[http://dx.doi.org/10.1016/j.clnu.2003.10.002] [PMID: 15158307]
[http://dx.doi.org/10.1007/s11883-007-0006-7] [PMID: 17877919]
[http://dx.doi.org/10.1016/j.pestbp.2016.06.003] [PMID: 28043333]
[http://dx.doi.org/10.1016/j.cmet.2010.12.008] [PMID: 21195345]
[http://dx.doi.org/10.1016/j.bbrc.2008.09.128] [PMID: 18845128]
[http://dx.doi.org/10.1016/j.abb.2012.03.018] [PMID: 22465028]
[http://dx.doi.org/10.1097/MOL.0b013e32834d1703] [PMID: 22101563]
[http://dx.doi.org/10.1002/mnfr.201500796] [PMID: 26872561]
[http://dx.doi.org/10.1021/acs.jafc.8b00850] [PMID: 29806464]
[http://dx.doi.org/10.1016/j.drudis.2007.07.024] [PMID: 17933690]
[http://dx.doi.org/10.1007/s11130-012-0318-9] [PMID: 23093401]
[http://dx.doi.org/10.1016/S0021-9150(01)00412-9] [PMID: 11500191]
[http://dx.doi.org/10.3390/nu11122844] [PMID: 31757033]
[http://dx.doi.org/10.1016/j.numecd.2014.09.001] [PMID: 25315667]
[http://dx.doi.org/10.1038/nrdp.2015.80] [PMID: 27188459]
[http://dx.doi.org/10.1080/13813455.2018.1444058] [PMID: 29482356]