Abstract
Background: Despite advances and the availability of newer drugs to facilitate childbirth, the interest in using natural treatments is on the rise. More than 20 percent of pregnancies require induction of labor, which is associated with side effects and increased risk of cesarean surgery. For this reason, the use of medicinal plants is considered healthier.
Objective: The present study is a systematic review of the role of oral herbs in facilitating childbirth.
Method: This review was conducted via searching the Medline/PubMed, Google Scholar, Scopus, and SID databases. The review began systematically and with no time constraints. It lasted until December 29, 2020.
Results: Twenty clinical trials investigated the impact of edible plants on increasing cervical readiness, stimulating labor onset, reducing pain intensity, and shortening the duration of labor. Five studies have revealed the positive impact of saffron. Two studies reported the same effect by chamomile. Three studies showed the positive impact of boiled dill seeds, and two studies showed the impact of date and date syrup. Another study reported the impact of Descurainia Sophia, and six studies also showed the positive effect of castor oil on uterine stimulation, strengthening and relieving labor pains, which eventually lead to facilitating labor. One study also showed no improvement in bishop score after consumption of primrose capsules.
Conclusion: The positive effect of edible medicinal plants on facilitating childbirth has been shown in the mentioned studies. However, more studies with a larger sample size are needed, and there is also a need for a more detailed study of the possible mechanisms of plant effects.
Keywords: Medicinal plants, facilitating childbirth, edible plants, childbirth, cesarean surgery.
[1]
Roqaiya M, Begum W, Majeedi SF, Saiyed A. A review on herbs with uterotonic property. J Phytopharmacol 2015; 4(3): 190-6.
[2]
Mlcek J, Rop O. Fresh edible flowers of ornamental plants–A new source of nutraceutical foods. Trends Food Sci Technol 2011; 22(10): 561-9.
[http://dx.doi.org/10.1016/j.tifs.2011.04.006]
[http://dx.doi.org/10.1016/j.tifs.2011.04.006]
[3]
Kelley KM, Behe BK, Biernbaum JA, Poff KL. Consumer preference for edible-flower color, container size, and price. HortScience 2001; 36(4): 801-4.
[http://dx.doi.org/10.21273/HORTSCI.36.4.801]
[http://dx.doi.org/10.21273/HORTSCI.36.4.801]
[4]
Lamxay V, de Boer HJ, Björk L. Traditions and plant use during pregnancy, childbirth and postpartum recovery by the Kry ethnic group in Lao PDR. J Ethnobiol Ethnomed 2011; 7(1): 14.
[http://dx.doi.org/10.1186/1746-4269-7-14] [PMID: 21569234]
[http://dx.doi.org/10.1186/1746-4269-7-14] [PMID: 21569234]
[5]
Ngoma CM, Siachapa B. Use of herbal medicines to induce labour by pregnant women: A systematic review of literature. JOJ Nurse Health Care 2017; 2(3): 1-5.
[http://dx.doi.org/10.19080/JOJNHC.2017.02.555590]
[http://dx.doi.org/10.19080/JOJNHC.2017.02.555590]
[6]
Ahmadi S, Aradmehr M, Azhari S. Saffron and childbirth; a triple blind clinical trial. QUID: Investigación. Ciencia y Tecnología 2017; (1): 2846-56.
[7]
Sadi R, Mohammad-Alizadeh-Charandabi S, Mirghafourvand M, Javadzadeh Y, Ahmadi-Bonabi A. Effect of saffron (Fan Hong Hua) on the readiness of the uterine cervix in term pregnancy: A placebo-controlled randomized trial. Iran Red Crescent Med J 2016; 18(10): e27241.
[http://dx.doi.org/10.5812/ircmj.27241] [PMID: 28180016]
[http://dx.doi.org/10.5812/ircmj.27241] [PMID: 28180016]
[8]
Gholami F, Neisani Samani L, Kashanian M, Naseri M, Hosseini AF, Hashemi Nejad SA. Onset of labor in post-term pregnancy by chamomile. Iran Red Crescent Med J 2016; 18(11): e19871.
[http://dx.doi.org/10.5812/ircmj.19871] [PMID: 28210497]
[http://dx.doi.org/10.5812/ircmj.19871] [PMID: 28210497]
[9]
Ramasubramaniam S, Renganathan L, Vijayalakshmi G, Mallo-Banatao MV. Use of herbal preparations among parturient women: Is there enough evidence-A review of literature. Int J Herb Med 2015; 2: 20-6.
[10]
Ghaderi S, Zaheri F, Nouri B, Shahoei R. The Effect of Honey Saffron Syrup on Labor Progression in Nulliparous Women. J Pharm Res Int 2019; 1-8.
[http://dx.doi.org/10.9734/jpri/2019/v28i430208]
[http://dx.doi.org/10.9734/jpri/2019/v28i430208]
[11]
Mohammadinia N, Rezaei MA, Loripour M, Vazirinezhad R. Assessment of the effect of Sisymbrium consumption on spontaneous labor in nulipars. Zahedan J Res Med Sci 2008; 10(2): 79-86.
[12]
Ghiasi A, Hasani M, Mollaahmadi L, Hashemzadeh M, Haseli A. The effect of aromatherapy on labor Pain relief: A systematic review of clinical trials. Majallah-i Zanan, Mamai va Nazai-i Iran 2017; 20(2): 89-105.
[13]
Jahdi F, Kalati M, Kashanian M, Naseri M, Haghani H. Effect of oral evening primrose capsules on ripening of the cervix in nulliparous iranian pregnant women (a randomized trial). Acta Medica Mediterranea 2016; 32(Specia): 1273-9.
[14]
Moayed MSNM, Yargholi M. Introducing medical substances(materia medica) which are effective on faciliating the childbirth in iranian traditional medicine. Med Hist 2014; 6(19): 153-66.
[15]
Oak G, Kurve P, Kurve S, Pejaver M. Ethno-botanical studies of edible plants used by tribal women of Thane District. J Med Plant Stud 2015; 3(2): 90-4.
[16]
Zamawe C, King C, Jennings HM, Mandiwa C, Fottrell E. Effectiveness and safety of herbal medicines for induction of labour: A systematic review and meta-analysis. BMJ Open 2018; 8(10): e022499.
[http://dx.doi.org/10.1136/bmjopen-2018-022499] [PMID: 30337313]
[http://dx.doi.org/10.1136/bmjopen-2018-022499] [PMID: 30337313]
[17]
Levine LD, Ed. Cervical ripening: Why we do what we do Seminars in perinatology Elsevier . 2020.
[18]
Torkzahrani S, Ghobadi K, Heshmat R, Shakeri N, Jalali Aria K. Effect of acupressure on cervical ripening. Iran Red Crescent Med J 2015; 17(8): e28691.
[http://dx.doi.org/10.5812/ircmj.28691] [PMID: 26430530]
[http://dx.doi.org/10.5812/ircmj.28691] [PMID: 26430530]
[19]
Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 2009; 62(10): e1-e34.
[http://dx.doi.org/10.1016/j.jclinepi.2009.06.006] [PMID: 19631507]
[http://dx.doi.org/10.1016/j.jclinepi.2009.06.006] [PMID: 19631507]
[20]
Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996; 17(1): 1-12.
[http://dx.doi.org/10.1016/0197-2456(95)00134-4] [PMID: 8721797]
[http://dx.doi.org/10.1016/0197-2456(95)00134-4] [PMID: 8721797]
[21]
Mohammadierad R, Mohammad-Alizadeh-Charandabi S, Mirghafourvand M, Fazil F. Effect of saffron with or without date sugar on intensity of pain and anxiety during labor in primiparous females: A randomized, controlled trial. Iran Red Crescent Med J 2018; 20(S1)
[http://dx.doi.org/10.5812/ircmj.61289]
[http://dx.doi.org/10.5812/ircmj.61289]
[22]
Ali-Akbari Sichani B, Darooneh T, Rashidi Fakari F, Moattar F, Nasiri M, Delpak-Yeganeh S. Effect of crocus sativus (Saffron) on cervical ripening and progress of labor in primiparous term women: A randomized double-blind placebo-controlled trial. Int J Pediatr 2020; 8(9): 12105-15.
[23]
Aradmehr M, Azhari S, Ahmadi S, Azmoude E. The effect of chamomile cream on episiotomy pain in Primiparous women: A randomized clinical trial. J Caring Sci 2017; 6(1): 19-28.
[http://dx.doi.org/10.15171/jcs.2017.003] [PMID: 28299294]
[http://dx.doi.org/10.15171/jcs.2017.003] [PMID: 28299294]
[24]
Chang SM, Chen CH. Effects of an intervention with drinking chamomile tea on sleep quality and depression in sleep disturbed postnatal women: A randomized controlled trial. J Adv Nurs 2016; 72(2): 306-15.
[http://dx.doi.org/10.1111/jan.12836] [PMID: 26483209]
[http://dx.doi.org/10.1111/jan.12836] [PMID: 26483209]
[25]
Eisenman SW, Zaurov DE, Struwe L. Medicinal plants of central Asia Uzbekistan and Kyrgyzstan: Springer Science & Business Media . 2012.
[26]
Fathi L, Amraei K. Effects of phoenix dactylifera syrup consumption on the severity of labor pain and length of the active phase of labor in nulliparous women. Iran J Nurs 2019; 31(116): 18-27.
[http://dx.doi.org/10.29252/ijn.31.116.18]
[http://dx.doi.org/10.29252/ijn.31.116.18]
[27]
Nimrouzi M, Zarshenas MM. Phytochemical and pharmacological aspects of Descurainia sophia Webb ex Prantl: modern and traditional applications. Avicenna J Phytomed 2016; 6(3): 266-72.
[PMID: 27462549]
[PMID: 27462549]
[28]
Holst L, Wright D, Haavik S, Nordeng H. Safety and efficacy of herbal remedies in obstetrics-review and clinical implications. Midwifery 2011; 27(1): 80-6.
[http://dx.doi.org/10.1016/j.midw.2009.05.010] [PMID: 19782445]
[http://dx.doi.org/10.1016/j.midw.2009.05.010] [PMID: 19782445]
[29]
Hekmatzadeh S, Mirmolaei S, Hoseini N. The effect of boiled dill (Anethum graveolens) seeds on the long active phase and labor pain intensity. Armaghane danesh 2012; 17(1): 50-9.
[30]
Hekmatzadeh SF, Aramesh S, Baashti S. Comparing the effect of boiled anethum graveolens seed with oxytocin on the duration of labor and pain in iranian women: A randomized clinical trial. Journal of Clinical Care and Skills 2020; 1(4): 165-70.
[http://dx.doi.org/10.52547/jccs.1.4.165]
[http://dx.doi.org/10.52547/jccs.1.4.165]
[31]
Akbari M, Javadnoori M, Siahpoosh A, Afshari P, Haghighi MH, Lake E. Comparison the effect of anethum graveolens and oxytocin on induction of labor in term pregnancy: A randomized clinical trial. Jundishapur J Nat Pharm Prod 2016; 11(1): e27876.
[32]
Kordi M, Aghaei Meybodi F, Tara F, Nematy M, Shakeri MT. The effect of date consumption in late pregnancy on the onset of labor in nulliparous women. Majallah-i Zanan, Mamai va Nazai-i Iran 2013; 16(77): 9-15.
[33]
Jadidi MY, Sang SJB, Lari H. The effect of date fruit consumption on spontaneous labor. J Pizhūhish dar dīn va salāmat 2015; 1(3): 4-10.
[34]
Khare CP. Indian medicinal plants: An illustrated dictionary Springer Science & Business Media. 2008, pp 717-718.
[35]
Beiranvand SP, Azhari S, Alizadeh ML, Shakeri M. The Effect of Castor oil on initiating labor in 40-42 weeks pregnancy. Majallah-i Danishgah-i Ulum-i Pizishki-i Babul 2007; 9: 33-8.
[36]
Gilad R, Hochner H, Savitsky B, Porat S, Hochner-Celnikier D. Castor oil for induction of labor in post-date pregnancies: A randomized controlled trial. Women Birth 2018; 31(1): e26-31.
[http://dx.doi.org/10.1016/j.wombi.2017.06.010] [PMID: 28750937]
[http://dx.doi.org/10.1016/j.wombi.2017.06.010] [PMID: 28750937]
[37]
Lamadah S, Mohamed H, El-Khedr S. Castor oil safety and effectiveness on labour induction and neonatal outcome. J Biol Agric Healthc 2014; 4(4)
[38]
Saberi F, Abedzadeh M, Saadat Z. The use of castor oil on cervical ripening in pregnancies. J Mazandaran Univ Med Sci 2008; 18(63): 11-9.
[39]
Iravani M, Montazeri S, Afshari P, Souri H. A study on the safety and efficacy of castor oil for cervical ripening and labour induction. 2006.
[40]
Kahnamoyiagdam F, Aghamohammadi M, Rostamnejad M. The effect of castor oil on the induction of labor: A clinical trial. Nursing Midwifery J 2014; 12(5): 348-53.
[41]
Azarkish F, Absalan N, Roudbari M, Barahooie F, Mirlashari S, Bameri M. Effect of oral castor oil on labor pain in post term pregnancy. Majallah-i Ilmi-i Danishgah-i Ulum-i Pizishki-i Kurdistan 2008; 13(3): 1-6.
[42]
Baker BP, Grant JA. Castor Oil Profile. Active ingredient eligible for minimum risk pesticide use 2018. Available from: http:// hdl.handle.net/1813/56115
[43]
Yousefi M, Hoseini MR, Salari R. Evaluating the clinical efficacy of Guggulu resin on constipation: A randomised clinical trial. Adv Integr Med 2016; 98-102.
[http://dx.doi.org/10.1016/j.aimed.2016.11.004]
[http://dx.doi.org/10.1016/j.aimed.2016.11.004]
[44]
Mahjoub F, Salari R, Yousefi M, Mohebbi M, Saki A, Rezayat KA. Effect of Pistacia atlantica kurdica gum on diabetic gastroparesis symptoms: A randomized, triple-blind placebo-controlled clinical trial. Electronic Physician 2018; 10(7): 6997-7007.
[http://dx.doi.org/10.19082/6997]
[http://dx.doi.org/10.19082/6997]
[45]
Bafor EE, Kupittayanant S. Medicinal plants and their agents that affect uterine contractility. Curr Opin Physiol 2020; 13: 20-6.
[http://dx.doi.org/10.1016/j.cophys.2019.09.004]
[http://dx.doi.org/10.1016/j.cophys.2019.09.004]
[46]
Jain A, Katewa SS, Chaudhary BL, Galav P. Folk herbal medicines used in birth control and sexual diseases by tribals of southern Rajasthan, India. J Ethnopharmacol 2004; 90(1): 171-7.
[http://dx.doi.org/10.1016/j.jep.2003.09.041] [PMID: 14698527]
[http://dx.doi.org/10.1016/j.jep.2003.09.041] [PMID: 14698527]
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