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ISSN (Print): 1573-4048
ISSN (Online): 1875-6581

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Clinical Trial

Concurrent Training for Women in Menopause: Protocol of a Randomized Controlled Clinical Trial

Author(s): Danielly Yani Fausto*, Juliana Araujo Klen, Adriane Pogere, Fabiana Flores Sperandio, Melissa de Carvalho Souza Vieira, Kettlyn Hames Alexandre and Adriana Coutinho de Azevedo Guimarães

Volume 18, Issue 4, 2022

Published on: 07 January, 2022

Article ID: e100921196368 Pages: 9

DOI: 10.2174/1573404817666210910115128

Price: $65

Abstract

Objective: To propose a concurrent training protocol and evaluate the effects on depressive symptoms, anxiety, mood, sexual function, body fat, muscular strength, cardiorespiratory capability, and hormonal profile of women in menopause through a randomized controlled trial.

Methods: This is a randomized clinical trial of two arms with 6 months of intervention with concurrent training with menopausal women (40 to 59 years old) with positive symptomatology to the Menopause Rating Scale (MRS) questionnaire and blood collection of Follicle Stimulating Hormone (FSH) ≥25 UI/ml, being randomly and distributed in two groups: experimental group (EG) and control group (CG). In the first trimester, there will be 30 minutes of aerobic training and 30 minutes of resistance training; in the second trimester, 40 minutes of aerobic training and 20 minutes of resistance training. The weekly frequency will be 3 times a week, with sessions lasting 60 minutes, going through a period of neuromuscular adaptation. The intensity will be increased each month according to individual needs. The control group will maintain its activities, normally receiving monthly calls to control and monitor its usual daily activities.

Main Outcome Measures: Comparative analyzes will be applied between the results of EG and CG after the intervention period, and also pre-and post-intragroup tests within both groups in order to observe possible changes after the intervention.

Conclusion: It is believed that this protocol is capable of treating the psychological, physical symptoms, hormonal profile, and sexual function of menopausal women.

Keywords: Aerobic exercise, clinical trial, clinical protocols, exercise, menopause, resistance training.

Graphical Abstract

[1]
Perlman B, Kulak D, Goldsmith LT, Weiss G. The etiology of menopause: Not just ovarian dysfunction but also a role for the central nervous system. Glob Reprod Heal 2018; 3(2): e8–e8.
[2]
Lambrinoudaki I. Lipid and glucose metabolism during the menopausal transition & beyond. Maturitas 2019; 124: 113.
[http://dx.doi.org/10.1016/j.maturitas.2019.04.010]
[3]
Lisboa LL, Utian W, da Fonseca Filho GG, de Azevedo GD. Tradução, adaptação e validação da versão brasileira do questionário utian quality of life para avaliação da qualidade de vida no climatério. Rev Bras Ginecol e Obs 2015; 37(11): 520-5.
[http://dx.doi.org/10.1590/SO100-720320150005438]
[4]
Heinemann LAJ, Potthoff P, Schneider HPG. International versions of the Menopause Rating Scale (MRS). Health Qual Life Outcomes 2003; 1: 28.
[http://dx.doi.org/10.1186/1477-7525-1-28] [PMID: 12914663]
[5]
Rindner L, Strömme G, Nordeman L, et al. Prevalence of somatic and urogenital symptoms as well as psychological health in women aged 45 to 55 attending primary health care: A cross-sectional study. BMC Womens Health 2017; 17(1): 128.
[http://dx.doi.org/10.1186/s12905-017-0480-1] [PMID: 29221473]
[6]
Velez MP, Alvarado BE, Rosendaal N, et al. Age at natural menopause and physical functioning in postmenopausal women: the Canadian Longitudinal Study on Aging. Menopause 2019; 26(9): 958-65.
[http://dx.doi.org/10.1097/GME.0000000000001362] [PMID: 31453956]
[7]
The NAMS 2017 Hormone Therapy Position Statement Advisory Panel. The 2017 hormone therapy position statement of The North American Menopause Society. Menopause 2017; 24(7): 728-53.
[http://dx.doi.org/10.1097/GME.0000000000000921] [PMID: 28650869]
[8]
Simoncini T, Cano A, Goulis DG, Lambrinoudaki I, Rees M, Stute P. On the use and abuse of register studies: The case of menopausal hormone therapy. Maturitas 2019; 123: 91-2.
[http://dx.doi.org/10.1016/j.maturitas.2019.03.009] [PMID: 30952373]
[9]
Braz A de S, de Paula AP, de Diniz FFM, de Almeida RN. Uso da terapia não farmacológica, medicina alternativa e complementar na fibromialgia. Rev Bras Reumatol 2011; 51(3): 275-82.
[http://dx.doi.org/10.1590/S0482-50042011000300008]
[10]
Erickson ML, Little JP, Gay JL, McCully KK, Jenkins NT. Effects of postmeal exercise on postprandial glucose excursions in people with type 2 diabetes treated with add-on hypoglycemic agents. Diabetes Res Clin Pract 2017; 126: 240-7.
[http://dx.doi.org/10.1016/j.diabres.2017.02.015] [PMID: 28284168]
[11]
Sternfeld B, Guthrie KA, Ensrud KE, et al. Efficacy of exercise for menopausal symptoms: A randomized controlled trial. Menopause 2014; 21(4): 330-8.
[http://dx.doi.org/10.1097/GME.0b013e31829e4089] [PMID: 23899828]
[12]
Berin E, Hammar M, Lindblom H, Lindh-Åstrand L, Rubér M, Spetz Holm AC. Resistance training for hot flushes in postmenopausal women: A randomised controlled trial. Maturitas 2019; 126: 55-60.
[http://dx.doi.org/10.1016/j.maturitas.2019.05.005] [PMID: 31239119]
[13]
Park KM, Park SC, Kang S. Effects of resistance exercise on adipokine factors and body composition in pre- and postmenopausal women. J Exerc Rehabil 2019; 15(5): 676-82.
[http://dx.doi.org/10.12965/jer.1938368.184] [PMID: 31723556]
[14]
Son W-M, Pekas EJ, Park S-Y. Twelve weeks of resistance band exercise training improves age-associated hormonal decline, blood pressure, and body composition in postmenopausal women with stage 1 hypertension: A randomized clinical trial. Menopause 2020; 27(2): 199-207.
[http://dx.doi.org/10.1097/GME.0000000000001444] [PMID: 31663986]
[15]
Wilson JM, Marin PJ, Rhea MR, Wilson SMC, Loenneke JP, Anderson JC. Concurrent training: A meta-analysis examining interference of aerobic and resistance exercises. J Strength Cond Res 2012; 26(8): 2293-307.
[http://dx.doi.org/10.1519/JSC.0b013e31823a3e2d] [PMID: 22002517]
[16]
Buonani C, Rossi FE, Diniz TA, Fortaleza AC, Viezel J, Picolo MR. Concurrent training and taurine improve lipid profile in postmenopausal women. Rev Bras Med Esporte 2019; 25(2): 121-6.
[http://dx.doi.org/10.1590/1517-869220192502196932]
[17]
Coll-Risco I, Borges-Cosic M, Acosta-Manzano P, Camiletti- Moirón D, Aranda P, Aparicio VA. Effects of concurrent exercise on cardiometabolic status during perimenopause: the FLAMENCO Project. Climacteric 2018; 21(6): 559-65.
[http://dx.doi.org/10.1080/13697137.2018.1526892] [PMID: 30392388]
[18]
Figueroa A, Park SY, Seo DY, Sanchez-Gonzalez MA, Baek YH. Combined resistance and endurance exercise training improves arterial stiffness, blood pressure, and muscle strength in postmenopausal women. Menopause 2011; 18(9): 980-4.
[http://dx.doi.org/10.1097/gme.0b013e3182135442] [PMID: 21540753]
[19]
Sociedade Portuguesa de Ginecologia. Consenso Nacional sobre Menopausa. Soc Port Ginecol 2016; p. 157.
[20]
Faul F, Erdfelder E, Lang A-G, Buchner A. G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 2007; 39(2): 175-91.
[http://dx.doi.org/10.3758/BF03193146] [PMID: 17695343]
[21]
Tartibian B, FitzGerald LZ, Azadpour N, Maleki BH. A randomized controlled study examining the effect of exercise on inflammatory cytokine levels in post-menopausal women. Post Reprod Health 2015; 21(1): 9-15.
[http://dx.doi.org/10.1177/2053369114565708] [PMID: 25710943]
[22]
Vieira S. Análise De Variância. Anova. Atlas 2006.
[23]
He L, Zhang X, Lv Y, Gu B, Zhao L. Effects of 8 weeks of moderate-intensity resistance training on muscle changes in postmenopausal women with different angiotensin-converting enzyme insertion/deletion polymorphisms of interest. Menopause 2019; 26(8): 899-905.
[http://dx.doi.org/10.1097/GME.0000000000001364] [PMID: 31124915]
[24]
Daley A, Thomas A, Roalfe A, Stokes-Lampard H, Coleman S, Rees M. The effectiveness of exercise as treatment for vasomotor menopausal symptoms: randomised controlled trial. BJOG An Int J Obstet Gynaecol 2015; 122(4): 565-75.
[http://dx.doi.org/10.1111/1471-0528.13193]
[25]
Luoto R, Moilanen J, Heinonen R, et al. Effect of aerobic training on hot flushes and quality of life- a randomized controlled trial. Ann Med 2012; 44(6): 616-26.
[http://dx.doi.org/10.3109/07853890.2011.583674] [PMID: 21639722]
[26]
Mansikkamäki K, Raitanen J, Nygård C-H, Heinonen R, Mikkola T, Tomás E. Sleep quality and aerobic training among menopausal women—A randomized controlled trial. Maturitas 2012; 72(4): 339-45.
[27]
Elavsky S, McAuley E. Physical activity and mental health outcomes during menopause: A randomized controlled trial. Ann Behav Med 2007; 33(2): 132-42.
[http://dx.doi.org/10.1007/BF02879894] [PMID: 17447865]
[28]
Ho TY, Redmayne GP, Tran A, et al. The effect of interval sprinting exercise on vascular function and aerobic fitness of post-menopausal women. Scand J Med Sci Sports 2020; 30(2): 312-21.
[http://dx.doi.org/10.1111/sms.13574] [PMID: 31603262]
[29]
Boutcher YN, Boutcher SH, Yoo HY, Meerkin JD. The Effect of Sprint Interval Training on Body Composition of Postmenopausal Women. Med Sci Sports Exerc 2019; 51(7): 1413-9.
[http://dx.doi.org/10.1249/MSS.0000000000001919] [PMID: 31210647]
[30]
Rossi FE, Diniz TA, Neves LM, et al. The beneficial effects of aerobic and concurrent training on metabolic profile and body composition after detraining: A 1-year follow-up in postmenopausal women. Eur J Clin Nutr 2017; 71(5): 638-45.
[http://dx.doi.org/10.1038/ejcn.2016.263] [PMID: 28120855]
[31]
American College of Sports Medicine. ACSM’s Guidelines for Exercise Testing and Prescription.Wolters Kluwer Health. (10th ed.),. 2018.
[32]
Nunes PRP, Martins FM, Souza AP, et al. Comparative effects of high-intensity interval training with combined training on physical function markers in obese postmenopausal women: A randomized controlled trial. Menopause 2019; 26(11): 1242-9.
[http://dx.doi.org/10.1097/GME.0000000000001399] [PMID: 31479035]
[33]
Rezende REF, Duarte SMB, Stefano JT, et al. Randomized clinical trial: benefits of aerobic physical activity for 24 weeks in postmenopausal women with nonalcoholic fatty liver disease. Menopause 2016; 23(8): 876-83.
[http://dx.doi.org/10.1097/GME.0000000000000647] [PMID: 27458060]
[34]
Borg G. Borg’s perceived exertion and pain scales. Manole. São Paulo 2000.
[35]
Burger HG, Hale GE, Robertson DM, Dennerstein L. A review of hormonal changes during the menopausal transition: focus on findings from the Melbourne Women’s Midlife Health Project. Hum Reprod Update 2007; 13(6): 559-65.
[http://dx.doi.org/10.1093/humupd/dmm020] [PMID: 17630397]
[36]
Monteleone P, Mascagni G, Giannini A, Genazzani AR, Simoncini T. Symptoms of menopause - global prevalence, physiology and implications. Nat Rev Endocrinol 2018; 14(4): 199-215.
[http://dx.doi.org/10.1038/nrendo.2017.180] [PMID: 29393299]
[37]
Abbas SZ, Sangawan V, Das A, Pandey AK. Assessment of cardiovascular risk in natural and surgical menopause. Indian J Endocrinol Metab 2018; 22(2): 223-8.
[http://dx.doi.org/10.4103/ijem.IJEM_620_17] [PMID: 29911036]
[38]
Carr MC. The emergence of the metabolic syndrome with menopause. J Clin Endocrinol Metab 2003; 88(6): 2404-11.
[http://dx.doi.org/10.1210/jc.2003-030242] [PMID: 12788835]
[39]
Ibrahim ZM, Ghoneim HM, Madny EH, et al. The effect of menopausal symptoms on the quality of life among postmenopausal Egyptian women. Climacteric 2020; 23(1): 9-16.
[http://dx.doi.org/10.1080/13697137.2019.1656185] [PMID: 31533486]
[40]
Wu S, Park K-S, McCormick JB. Effects of Exercise Training on Fat Loss and Lean Mass Gain in Mexican-American and Korean Premenopausal Women. Int J Endocrinol 2017; 2017: 5465869.
[http://dx.doi.org/10.1155/2017/5465869] [PMID: 28761442]
[41]
Jones SMW, Guthrie KA, Reed SD, et al. A yoga & exercise randomized controlled trial for vasomotor symptoms: Effects on heart rate variability. Complement Ther Med 2016; 26: 66-71.
[http://dx.doi.org/10.1016/j.ctim.2016.03.001] [PMID: 27261984]

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