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CNS & Neurological Disorders - Drug Targets

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Review Article

Implication of Covid-19 on Neurological Complications with Specific Emphasis on Alzheimer’s and Parkinson’s Disease

Author(s): Ankita Sood, Ravi Goyal, Harshdeep Singh, Tapan Behl, Sandeep Arora, Balraj Saini and Rajwinder Kaur*

Volume 21, Issue 3, 2022

Published on: 20 August, 2021

Page: [235 - 245] Pages: 11

DOI: 10.2174/1871527320666210820092817

Price: $65

Abstract

It is noticeable how the novel coronavirus has spread from the Wuhan region of China to the whole world, devastating the lives of people worldwide. All the data related to the precautionary measures, diagnosis, treatment, and even the epidemiological data are being made freely accessible and reachable in a very little time as well as being rapidly published to save humankind from this pandemic. There might be neurological complications of COVID-19 and patients suffering from neurodegenerative conditions like Alzheimer’s disease and Parkinson’s disease might have repercussions as a result of the pandemic. In this review article, we have discussed the effect of SARS-CoV-2 viral infection on the people affected with neurodegenerative disorders such as Parkinson’s and Alzheimer’s. It primarily emphasizes two issues, i.e., vulnerability to infection and modifications of course of the disease concerning the clinical neurological manifestations, the advancement of the disease and novel approaches to support health care professionals in disease management, the susceptibility to these diseases, and impact on the severity of disease and management.

Keywords: COVID-19, CNS, Alzheimer’s disease, Parkinson’s disease, neurological complications, pneumonia

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