Abstract
Introduction: Pheochromocytoma are tumors arising from the chromaffin tissue located in the adrenal medulla, associated with typical symptoms and signs.
Case Presentation: Occasionally, metastasis, defined as the presence of tumor cells at sites other than the original site, secondary to pheochromocytoma have been reported. Pelvic metastatic malignant pheochromocytoma has rarely been reported in English literature.
Conclusion: Here, we have reported a very rare case of pelvic metastatic malignant pheochromocytoma, with a particular focus on sonoelastographic features.
Keywords: Pheochromocytoma, malignant pheochromocytoma, pheochromocytoma, extra-Adrenal, ultrasonography, sonoelastography.
Graphical Abstract
[1]
Blake MA, Kalra MK, Maher MM, et al. Pheochromocytoma: an imaging chameleon. Radiographics 2004; 24(Suppl. 1): S87-99.
[http://dx.doi.org/10.1148/rg.24si045506] [PMID: 15486252]
[http://dx.doi.org/10.1148/rg.24si045506] [PMID: 15486252]
[2]
Leung K, Stamm M, Raja A, Low G. Pheochromocytoma: the range of appearances on ultrasound, CT, MRI, and functional imaging. AJR Am J Roentgenol 2013; 200(2): 370-8.
[http://dx.doi.org/10.2214/AJR.12.9126] [PMID: 23345359]
[http://dx.doi.org/10.2214/AJR.12.9126] [PMID: 23345359]
[3]
Zelinka T, Musil Z, Dušková J, et al. Metastatic pheochromocytoma: does the size and age matter? Eur J Clin Invest 2011; 41(10): 1121-8.
[http://dx.doi.org/10.1111/j.1365-2362.2011.02518.x] [PMID: 21692797]
[http://dx.doi.org/10.1111/j.1365-2362.2011.02518.x] [PMID: 21692797]
[4]
Sigrist RMS, Liau J, Kaffas AE, Chammas MC, Willmann JK. Ultrasound elastography: Review of techniques and clinical applications. Theranostics 2017; 7(5): 1303-29.
[http://dx.doi.org/10.7150/thno.18650] [PMID: 28435467]
[http://dx.doi.org/10.7150/thno.18650] [PMID: 28435467]
[5]
Wang B, Zhang Y, Chen S, et al. Diagnostic accuracy of cervical elastography in predicting preterm delivery: A systematic review and meta-analysis. Medicine (Baltimore) 2019; 98(29): e16449.
[http://dx.doi.org/10.1097/MD.0000000000016449] [PMID: 31335700]
[http://dx.doi.org/10.1097/MD.0000000000016449] [PMID: 31335700]
[6]
Tavare AN, Alfuraih AM, Hensor EMA, Astrinakis E, Gupta H, Robinson P. Shear-wave elastography of benign versus malignant musculoskeletal soft-tissue masses: Comparison with conventional US and MRI. Radiology 2019; 290(2): 410-7.
[http://dx.doi.org/10.1148/radiol.2018180950] [PMID: 30480491]
[http://dx.doi.org/10.1148/radiol.2018180950] [PMID: 30480491]
[7]
Park SB, Kang BS. Value of ultrasonographic evaluation for soft-tissue lesions: focus on incidentally detected lesions on CT/MRI. Jpn J Radiol 2017; 35(9): 485-94.
[http://dx.doi.org/10.1007/s11604-017-0657-4] [PMID: 28608002]
[http://dx.doi.org/10.1007/s11604-017-0657-4] [PMID: 28608002]
[8]
Sang L, Wang XM, Xu DY, Cai YF. Accuracy of shear wave elastography for the diagnosis of prostate cancer: A meta-analysis. Sci Rep 2017; 7(1): 1949.
[http://dx.doi.org/10.1038/s41598-017-02187-0] [PMID: 28512326]
[http://dx.doi.org/10.1038/s41598-017-02187-0] [PMID: 28512326]
[9]
Sun LT, Ning CP, Liu YJ, et al. Is transvaginal elastography useful in pre-operative diagnosis of cervical cancer? Eur J Radiol 2012; 81(8): e888-92.
[http://dx.doi.org/10.1016/j.ejrad.2012.04.025] [PMID: 22717123]
[http://dx.doi.org/10.1016/j.ejrad.2012.04.025] [PMID: 22717123]
[10]
Zhang M, Wasnik AP, Masch WR, et al. Transvaginal ultrasound shear wave elastography for the evaluation of benign uterine pathologies: A prospective pilot study. J Ultrasound Med 2019; 38(1): 149-55.
[http://dx.doi.org/10.1002/jum.14676] [PMID: 29732594]
[http://dx.doi.org/10.1002/jum.14676] [PMID: 29732594]
[11]
Andres MP, Borrelli GM, Ribeiro J, Baracat EC, Abrão MS, Kho RM. Transvaginal ultrasound for the diagnosis of adenomyosis: systematic review and meta-analysis. J Minim Invasive Gynecol 2018; 25(2): 257-64.
[http://dx.doi.org/10.1016/j.jmig.2017.08.653] [PMID: 28864044]
[http://dx.doi.org/10.1016/j.jmig.2017.08.653] [PMID: 28864044]
[12]
Che D, Wei H, Yang Z, Zhang Y, Ma S, Zhou X. Application of transvaginal sonographic elastography to distinguish endometrial cancer from benign masses. Am J Transl Res 2019; 11(2): 1049-57.
[PMID: 30899404]
[PMID: 30899404]
[13]
Preis K, Zielinska K, Swiatkowska-Freund M, Wydra D, Kobierski J. The role of elastography in the differential diagnosis of endometrial pathologies- preliminary report. Ginekol Pol 2011; 82(7): 494-7.
[PMID: 21913425]
[PMID: 21913425]
[14]
Czuczwar P, Wozniak S, Szkodziak P, Kudla MJ, Pyra K, Paszkowski T. Elastography improves the diagnostic accuracy of sonography in differentiating endometrial polyps and submucosal fibroids. J Ultrasound Med 2016; 35(11): 2389-95.
[http://dx.doi.org/10.7863/ultra.15.12017] [PMID: 27629761]
[http://dx.doi.org/10.7863/ultra.15.12017] [PMID: 27629761]
[15]
Woźniak S. The potential role of elastography in differentiating between endometrial polyps and submucosal fibroids: a preliminary study. Przegl Menopauz 2015; 14(2): 130-3.
[http://dx.doi.org/10.5114/pm.2015.52123] [PMID: 26327901]
[http://dx.doi.org/10.5114/pm.2015.52123] [PMID: 26327901]
[16]
Londero AP, Schmitz R, Bertozzi S, Driul L, Fruscalzo A. Diagnostic accuracy of cervical elastography in predicting labor induction success: a systematic review and meta-analysis. J Perinat Med 2016; 44(2): 167-78.
[http://dx.doi.org/10.1515/jpm-2015-0035] [PMID: 26011923]
[http://dx.doi.org/10.1515/jpm-2015-0035] [PMID: 26011923]
[17]
Kim KY, Kim JH, Hong AR, et al. Disentangling of malignancy from benign pheochromocytomas/paragangliomas. PLoS One 2016; 11(12): e0168413.
[http://dx.doi.org/10.1371/journal.pone.0168413] [PMID: 27992508]
[http://dx.doi.org/10.1371/journal.pone.0168413] [PMID: 27992508]
[18]
Hernandez-Andrade E, Aurioles-Garibay A, Garcia M, et al. Effect of depth on shear-wave elastography estimated in the internal and external cervical os during pregnancy. J Perinat Med 2014; 42(5): 549-57.
[http://dx.doi.org/10.1515/jpm-2014-0073] [PMID: 25029081]
[http://dx.doi.org/10.1515/jpm-2014-0073] [PMID: 25029081]
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