摘要
背景:天然生物聚合物因其良好的生物相容性、生物降解性、可再生性以及各种反应官能团可用于修饰和引入新组分而受到广泛关注。在过去的几年里,人们开发了大量的天然生物聚合物复合材料,以改善其物理和化学性能,并添加新的功能。 方法:本文综述了海藻酸盐、壳聚糖和明胶三种常见的天然生物聚合物基复合材料的研究进展。 结果:对这些生物聚合物复合材料的形貌特征、制备方法和独特的功能进行了分析和讨论。 结论:最后,本文综述了近年来生物医学领域的主要应用,如组织工程、伤口愈合和药物传递等方面的研究进展,并展望了具有定制力学性能和稳定特性的生物聚合物复合材料在医药和生物医学领域的进一步发展。
关键词: 天然生物聚合物,复合材料,合成,生物医学应用,人造血管,生物相容性。
Current Medicinal Chemistry
Title:Recent Progress in the Synthesis and Biomedical Properties of Natural Biopolymer Composites
Volume: 28 Issue: 40
关键词: 天然生物聚合物,复合材料,合成,生物医学应用,人造血管,生物相容性。
摘要:
Background: Natural biopolymers have drawn extensive attention because of their great biocompatibility, biodegradability, renewability, and the availability of various reactive functional groups for modifying and introducing novel components. In the last few years, numerous natural biopolymer composites have been exploited to improve their physical and chemical properties and add new functionalities.
Methods: Herein, we summarize the current progress in three common classes of natural biopolymer-based composites, including alginate, chitosan, and gelatin.
Results: The morphology characteristics, preparation methods, and unique functionalities of these biopolymer composites are also analyzed and discussed.
Conclusion: Finally, the article offers an overview of recent progress in the main biomedical applications such as tissue engineering, wound-healing, and drug delivery, which inspires further progress in biopolymer composites with tailored mechanical property and stable characteristics for pharmaceutical and biomedical applications.
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Cite this article as:
Recent Progress in the Synthesis and Biomedical Properties of Natural Biopolymer Composites, Current Medicinal Chemistry 2021; 28 (40) . https://dx.doi.org/10.2174/0929867328666201217104038
DOI https://dx.doi.org/10.2174/0929867328666201217104038 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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