Abstract
To review the treatments currently used to treat mycobacteria (latent tuberculosis, clinical tuberculosis, infections due to mycobacteria), focussing on : Doses administered and duration of treatment Levels reached in different body tissues in relation to the chemical characteristics of the drugs The relation between these data and the microbiological parameters of each microorganism To review the above parameters for the new groups of drugs being investigated for treatment of the three pathologies. a. fluorquinolones b. macrolides c. rifampicins d. oxazolidinones e. tetracyclines f.- other drugs undergoing investigation
Keywords: Mycobacterium tuberculosis, rifampicin resistance, fluoroquinolones, Mycobacterium avium, M-DCMG conjugate
Anti-Infective Agents in Medicinal Chemistry
Title: Present and Future Treatment of Mycobacteria
Volume: 7 Issue: 1
Author(s): J. C. Rodriguez, I. Escribano, R. A. Gomez, E. Garcia Pachon, A. Navarro and G. Royo
Affiliation:
Keywords: Mycobacterium tuberculosis, rifampicin resistance, fluoroquinolones, Mycobacterium avium, M-DCMG conjugate
Abstract: To review the treatments currently used to treat mycobacteria (latent tuberculosis, clinical tuberculosis, infections due to mycobacteria), focussing on : Doses administered and duration of treatment Levels reached in different body tissues in relation to the chemical characteristics of the drugs The relation between these data and the microbiological parameters of each microorganism To review the above parameters for the new groups of drugs being investigated for treatment of the three pathologies. a. fluorquinolones b. macrolides c. rifampicins d. oxazolidinones e. tetracyclines f.- other drugs undergoing investigation
Export Options
About this article
Cite this article as:
Rodriguez C. J., Escribano I., Gomez A. R., Pachon Garcia E., Navarro A. and Royo G., Present and Future Treatment of Mycobacteria, Anti-Infective Agents in Medicinal Chemistry 2008; 7 (1) . https://dx.doi.org/10.2174/187152108783329816
DOI https://dx.doi.org/10.2174/187152108783329816 |
Print ISSN 1871-5214 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6018 |
Related Articles
-
Preface
Recent Patents on Anti-Infective Drug Discovery In silico Analysis of Several Signal Peptides for the Excretory Production of Reteplase in Escherichia coli
Current Proteomics Recent Advances in Clinical Immunology, Endocrine & Metabolic Drugs: An Editorial Overview
Clinical Immunology, Endocrine & Metabolic Drugs (Discontinued) Cytokines as Immunomodulators in Tuberculosis Therapy
Recent Patents on Anti-Infective Drug Discovery Virtual Screening of Drugs: Score Functions, Docking, and Drug Design
Current Computer-Aided Drug Design Reverse Pharmacognosy: Another Way to Harness the Generosity of Nature
Current Pharmaceutical Design The Role of Vitamin D in Prevention and Treatment of Infection
Inflammation & Allergy - Drug Targets (Discontinued) Synthesis and Antitumoral Evaluation of 7-chloro-4-quinolinylhydrazones Derivatives
Medicinal Chemistry Dried Blood Spots: A New Tool for Tuberculosis Treatment Optimization
Current Pharmaceutical Design Anti-Inflammatory Trends of 1, 3-Diphenyl-2-propen-1-one Derivatives
Mini-Reviews in Medicinal Chemistry In Vitro Screening of Some Heterocyclic Compounds Against Human ABHD6 and ABHD12 Hydrolases
Letters in Drug Design & Discovery Vaccines and Vaccine Strategies Against HIV
Current Drug Targets Efflux Pumps of Gram-Negative Bacteria, a New Target for New Molecules
Current Topics in Medicinal Chemistry Nitric Dioxide as Biologically Important Radical and its Role in Molecular Mechanism of Pancreatic Inflammation
Current Pharmaceutical Analysis Editorial (Thematic Issue: From Nuisance to State-of-the-Art: FDG-PET/CT Imaging of Infection and Inflammation)
Current Molecular Imaging (Discontinued) Nano-carriers for the Treatment of Tuberculosis
Recent Patents on Anti-Infective Drug Discovery An Overview of Neolignans of the Genus Piper L.: Isolation Methods and Biological Activities
Mini-Reviews in Medicinal Chemistry miR-202 Mediates Metabolic Shift in Lung Cancer Cells via Targeting HK2
Current Signal Transduction Therapy Computational Approaches as Rational Decision Support Systems for Discovering Next-Generation Antitubercular Agents: Mini-Review
Current Computer-Aided Drug Design Patent Selections
Recent Patents on Inflammation & Allergy Drug Discovery