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Current Green Chemistry

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ISSN (Print): 2213-3461
ISSN (Online): 2213-347X

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General Research Article

Visible Light Assisted Synthesis of 5-Aryl-1,2,4-thiazolidine-3-thiones Under Catalyst-free Condition

Author(s): Amol Khandebharad*, Swapnil Sarda, Pravin Kulkarni and Brijmohan Agrawal

Volume 7, Issue 3, 2020

Page: [326 - 333] Pages: 8

DOI: 10.2174/2213346107999200729131533

Price: $65

Abstract

Light energy can be considered as an ideal eco-friendly source of energy for green chemistry. This perspective was used to synthesize 5-aryl-1,2,4-thiazolidine-3-thiones derivative as a quick, efficient and highly improved protocol. The present method developed an energy competent and integrated technique by one-pot condensations of aromatic aldehyde and thiosemicarbazide under the catalyst-free condition in aqueous-alcoholic media. The impact of light on reaction along with mechanical stirring provided a prominent yield of the product. The mild reaction conditions, short reaction time and easy workup procedure, avoidance of heavy metal catalyst and harsh reaction conditions make this protocol greener.

Keywords: Aromatic aldehyde, thiosemicarbazide, water: ethanol (1:1), visible light, thio-triazole derivatives, green chemistry.

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