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Current Cardiology Reviews

Editor-in-Chief

ISSN (Print): 1573-403X
ISSN (Online): 1875-6557

Review Article

Fascicular Blocks: Update 2019

Author(s): Marcelo V. Elizari*

Volume 17, Issue 1, 2021

Published on: 08 July, 2020

Page: [31 - 40] Pages: 10

DOI: 10.2174/1573403X16666200708111928

Price: $65

Abstract

Many advances in the knowledge of medical science are due to the observation of an unknown phenomenon that remains an open question. A plausible hypothesis must be demonstrated and proved through a scientific method in order to be accepted by the scientific community and the same results must be reached by following either the same or different techniques. The original case described by Rosenbaum MB et al., in this review triggered a series of anatomic and physiologic investigations with clinical and experimental observations that supported the trifascicular nature of the intraventricular conduction system of the heart and the concept of hemiblocks. The recognition and description of the left fascicular blocks made by the Argentinian School of Electrocardiology bridged an important gap in electrocardiography and many electrocardiograms that could not be explained until that moment could finally be understood. This review intends to redefine reliable criteria for the electrocardiographic and vectorcardiographic diagnosis of left fascicular blocks [hemiblocks]. The anatomy of the left bundle branch is also discussed to better understand the incidence, prevalence, clinical significance and main causes of left anterior and left posterior hemiblock either isolated or associated with right bundle branch block. This review offers the reader a reappraisal of the trifascicular nature of the intraventricular conduction system regarding the anatomy of the left bundle branch system and its pathophysiological and clinical significance.

Keywords: Fascicular blocks, intraventricular conduction system, hemiblocks, electrocardiography, left bundle branch block, right bundle branch block.

Graphical Abstract

[1]
Eppinger H, Stoerk O. Zur Klinik des Electrokardiogramms. Klin Med (Mosk) 1910; 71: 157-64.
[2]
Barker PS, Mcleod AG, Alexander J. The excitatory process observed in the exposed human heart. Am Heart J 1930; 5: 720-42.
[http://dx.doi.org/10.1016/S0002-8703(30)90088-9]
[3]
Wilson FN, Mcleod AG, Barker PS. The interpretation of the initial deflections of the ventricular complex of the electrocardiogram. Am Heart J 1931; 6: 637-64.
[http://dx.doi.org/10.1016/S0002-8703(31)90439-0]
[4]
Rosenbaum MB, Elizari MV, Lázzari JO. Los hemibloqueos. Buenos Aires: Editorial Paidós 1968.
[5]
Rosenbaum MB, Elizari MV, Lázzari JO. The hemiblocks New concepts of intraventricular conduction based on human anatomical, physiological and clinical studies 1970.
[6]
Rosenbaum MB, Elizari MV, Lázzari JO. Gli Emiblocchi. Padova, Italia: Piccin Editore 1976.
[7]
Elizari MV. The normal variants in the left bundle branch system. J Electrocardiol 2017; 50(4): 389-99.
[http://dx.doi.org/10.1016/j.jelectrocard.2017.03.004] [PMID: 28341304]
[8]
Spach MS, Huang S, Armstrong SI, Canent RV Jr. Demonstration of the peripheral conduction system in human hearts. Circulation 1963; 28: 333-8.
[http://dx.doi.org/10.1161/01.CIR.28.3.333] [PMID: 14059452]
[9]
Uhley HN, Rivkin LM. Visualization of the left branch of the human atrioventricular bundle. Circulation 1959; 20: 419-21.
[http://dx.doi.org/10.1161/01.CIR.20.3.419] [PMID: 13840232]
[10]
MacAlpin RN. In search of left septal fascicular block. Am Heart J 2002; 144(6): 948-56.
[http://dx.doi.org/10.1067/mhj.2002.125503] [PMID: 12486419]
[11]
Pérez Riera AR, Ferreira C, Ferreira Filho C, et al. Electrovectorcardiographic diagnosis of left septal fascicular block: anatomic and clinical considerations. Ann Noninvasive Electrocardiol 2011; 16(2): 196-207.
[http://dx.doi.org/10.1111/j.1542-474X.2011.00416.x] [PMID: 21496172]
[12]
Lenègre J. Contribution à l’Étude des Blocs de Branche. Paris: JB Baillière et Fils 1958.
[13]
Lev M. Anatomic basis for atrioventricular block. Am J Med 1964; 37: 742-8.
[http://dx.doi.org/10.1016/0002-9343(64)90022-1] [PMID: 14237429]
[14]
Rossi L. Histopathologic features of cardiac arrhythmias. Milano: Casa Editrice Ambrosiana 1969.
[15]
Elizari MV, Chiale PA. The electrocardiographic features of complete and partial left anterior and left posterior hemiblock. J Electrocardiol 2012; 45(5): 528-35.
[http://dx.doi.org/10.1016/j.jelectrocard.2012.06.012] [PMID: 22920788]
[16]
Rosenbaum MB, Halpern MS, Nau GJ, Elizari MV, Lázari JO. The mechanism of narrow ventricular ectopic beats. In: Flensten-Jensen Sandøe E, Ed. Symposium of Cardiac Arrhythmias.
[17]
Benchimol A, Ed. The Williams & Wilkins Co. Baltimore, Md., USA 1973.
[18]
Castellanos A Jr, Myerburg RJ. The Hemiblocks in Myocardial Infarction Appleton Century-Crofts. New York, USA 1976.
[19]
Lévy S. Bundle branch blocks and/or hemiblocks complicating acute myocardial ischemia or infarction. J Interv Card Electrophysiol 2018; 52(3): 287-92.
[http://dx.doi.org/10.1007/s10840-018-0430-3] [PMID: 30136134]
[20]
Elizari MV, Acunzo RS, Ferreiro M. Hemiblocks revisited. Circulation 2007; 115(9): 1154-63.
[http://dx.doi.org/10.1161/CIRCULATIONAHA.106.637389] [PMID: 17339573]
[21]
Canaveris G, Halpern MS, Elizari MV. Intraventricular conduction disturbances in civilian flying personnel: left anterior hemiblock. Aviat Space Environ Med 1992; 63(4): 292-8.
[PMID: 1610340]
[22]
Elizari MV, Ansaldi MS, Chiale PA, et al. Cierre espontáneo de la comunicación interventricular. Una causa ignorada de trastornos de la conducción aurículoventricular e intraventricular. Rev Arg Cardiol 1996; 64: 165-74.
[23]
Krivisky M, Aberbouch L, Shochat I, Ribak J, Tamir A, Froom P. Left anterior hemiblock in otherwise healthy pilots. Aviat Space Environ Med 1988; 59(7): 651-2.
[PMID: 3408426]
[24]
Rosenbaum MB. Chagasic myocardiopathy. Prog Cardiovasc Dis 1964; 7: 199-225.
[http://dx.doi.org/10.1016/S0033-0620(64)80020-7] [PMID: 14223289]
[25]
Durrer D, Roos JP, van Dam RT. The genesis of the electrocardiogram of patients with ostium primum defects (ventral atrial septal defects). Am Heart J 1966; 71(5): 642-50.
[http://dx.doi.org/10.1016/0002-8703(66)90314-0] [PMID: 5935856]
[26]
Wesselhoeft H, Fawcett JS, Johnson AL. Anomalous origin of the left coronary artery from the pulmonary trunk. Its clinical spectrum, pathology, and pathophysiology, based on a review of 140 cases with seven further cases. Circulation 1968; 38(2): 403-25.
[http://dx.doi.org/10.1161/01.CIR.38.2.403] [PMID: 5666852]
[27]
Noonan JA. Hypertelorism with Turner phenotype. A new syndrome with associated congenital heart disease. Am J Dis Child 1968; 116(4): 373-80.
[http://dx.doi.org/10.1001/archpedi.1968.02100020377005] [PMID: 4386970]
[28]
Lev M. Conduction system in congenital heart disease. Am J Cardiol 1968; 21(5): 619-27.
[http://dx.doi.org/10.1016/0002-9149(68)90259-2] [PMID: 5645077]
[29]
Brink AJ, Neill CA. The electrocardiogram in congenital heart disease; with special reference to left axis deviation. Circulation 1955; 12(4): 604-11.
[http://dx.doi.org/10.1161/01.CIR.12.4.604] [PMID: 13261312]
[30]
Elliott LP, Ruttenberg HD, Eliot RS, Anderson RC. Vectorial analysis of the electrocardiogram in common ventricle. Br Heart J 1964; 26(3): 302-11.
[http://dx.doi.org/10.1136/hrt.26.3.302] [PMID: 14156079]
[31]
Heggtveit HA. Congenital aneurysm of the membranous septum associated with bundle branch block. Am J Cardiol 1964; 14: 112-7.
[http://dx.doi.org/10.1016/0002-9149(64)90115-8] [PMID: 14176880]
[32]
Yang SS, Maranhao V, Ablaza SG, Morse DP, Goldberg H. Aneurysm of the membranous portion of the ventricular septum. Am J Cardiol 1969; 23(1): 83-8.
[http://dx.doi.org/10.1016/0002-9149(69)90245-8] [PMID: 5380844]
[33]
Aravindakshan V, Elizari MV, Rosenbaum MB. Right bundle-branch block and left anterior fascicular block (left anterior hemiblock) following tricuspid valve replacement. Circulation 1970; 42(5): 895-902.
[http://dx.doi.org/10.1161/01.CIR.42.5.895] [PMID: 5482354]
[34]
Rosenbaum MB, Corrado G, Oliveri R, Castellanos A Jr, Elizari MV. Right bundle branch block with left anterior hemiblock surgically induced in tetralogy of Fallot. Relation to the mechanism of electrocardiographic changes in endocardial cushion defects. Am J Cardiol 1970; 26(1): 12-9.
[http://dx.doi.org/10.1016/0002-9149(70)90752-6] [PMID: 5427826]
[35]
Wolff GS, Rowland TW, Ellison RC. Surgically induced right bundle-branch block with left anterior hemiblock. An ominous sign in postoperative tetralogy of Fallot. Circulation 1972; 46(3): 587-94.
[http://dx.doi.org/10.1161/01.CIR.46.3.587] [PMID: 5071742]
[36]
Richman JL, Wolff L. Left bundle branch block masquerading as right bundle branch block. Am Heart J 1954; 47: 383-93.
[http://dx.doi.org/10.1016/0002-8703(54)90295-1]
[37]
Elizari MV, Baranchuk A, Chiale PA. Masquerading bundle branch block: a variety of right bundle branch block with left anterior fascicular block. Expert Rev Cardiovasc Ther 2013; 11(1): 69-75.
[http://dx.doi.org/10.1586/erc.12.142] [PMID: 23259447]
[38]
Anderson KP. Left bundle branch block and the evolving role of QRS morphology in selection of patients for cardiac resynchronization. J Interv Card Electrophysiol 2018; 52(3): 353-74.
[http://dx.doi.org/10.1007/s10840-018-0426-z] [PMID: 30128803]
[39]
Uhley HN. The concept of trifascicular intraventricular conduction: historical aspects and influence on contemporary cardiology. Am J Cardiol 1979; 43(3): 643-6.
[http://dx.doi.org/10.1016/0002-9149(79)90025-0] [PMID: 369350]
[40]
Hecht HH. The Hemiblocks Rosenbaum MB, Elizari MV, Lazzari JO [eds] Tampa Tracings, Florida. 1970.
[41]
Demoulin JC, Kulbertus HE. Histopathological examination of concept of left hemiblock. Br Heart J 1972; 34(8): 807-14.
[http://dx.doi.org/10.1136/hrt.34.8.807] [PMID: 5070112]
[42]
Kulbertus HE, Demoulin JC. Pathologial Basis of Concept of Left Hemiblock. The Conduction System of the Heart Wellens HJJ, Lie KI, Janse MJ [eds]. H. E Stenfert Kroese BV, Leiden 1976.
[43]
Durrer D, van Dam RT, Freud GE, Janse MJ, Meijler FL, Arzbaecher RC. Total excitation of the isolated human heart. Circulation 1970; 41(6): 899-912.
[http://dx.doi.org/10.1161/01.CIR.41.6.899] [PMID: 5482907]
[44]
Myerburg RJ, Nilsson K, Gelband H. Physiology of canine intraventricular conduction and endocardial excitation. Circ Res 1972; 30(2): 217-43.
[http://dx.doi.org/10.1161/01.RES.30.2.217] [PMID: 5061320]
[45]
Bayés de Luna A, Riera AP, Baranchuk A, et al. Electrocardiographic manifestation of the middle fibers/septal fascicle block: a consensus report. J Electrocardiol 2012; 45(5): 454-60.
[http://dx.doi.org/10.1016/j.jelectrocard.2012.06.002] [PMID: 22920784]
[46]
Alboni P. Intraventricular Conduction Disturbances. The Hague: Martinus Nihoff Pub. 1981.
[http://dx.doi.org/10.1007/978-94-009-8287-1]
[47]
Surawicz B, Childers R, Deal BJ, et al. AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part III: intraventricular conduction disturbances: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society: endorsed by the International Society for Computerized Electrocardiology. Circulation 2009; 119(10): e235-40.
[http://dx.doi.org/10.1161/CIRCULATIONAHA.108.191095] [PMID: 19228822]
[48]
MacAlpin RN. Left septal fascicular block: myth or reality? Indian Pacing Electrophysiol J 2003; 3(3): 157-77.
[PMID: 16943914]
[49]
Hoffman I. Quadrifascicular? J Electrocardiol 2012; 45(5): 536-8.
[http://dx.doi.org/10.1016/j.jelectrocard.2012.06.010] [PMID: 22809571]
[50]
de Pádua F, dos Reis DD, Lopes VM, et al. Left median hemiblock-a chimera? Adv Cardiol 1978; 21: 242-8.
[http://dx.doi.org/10.1159/000400459] [PMID: 619547]
[51]
Tawara S. Das Reizleitunssystem des Saugetierherzens. Jena: G. Fischer 1906.
[52]
Holl M. Makroskopische Darstellung der Atrioventikularen Verbindungsbundels am menschlichen und tierischen Herzen Denkschr D math Nat Kl D kais Akad d Wiss. Viena 1911; p. 87.
[53]
Lewis T. The Mechanism and Graphic Registration of the Heart Beat. London: Shaw Sons Ltd. 1925.
[54]
Mahaim I. Les Maladies Organiques du Faisceau de HisTawara. Paris: Masson et Cie 1931.
[55]
Lev M, Widran J, Erickson EE. A method for the histopathologic study of the atrioventricular node, bundle, and branches. AMA Arch Pathol 1951; 52(1): 73-83.
[PMID: 14837568]
[56]
Read JL, Hegre ES, Russi S. Reaffirmation of the auriculoventricular conduction system in man; the introduction of a unique technic for its serial motion picture reconstruction. Circulation 1953; 7(1): 42-51.
[http://dx.doi.org/10.1161/01.CIR.7.1.42] [PMID: 13019917]
[57]
Titus JL, Daugherty GW, Edwards JE. Anatomy of the normal human atrioventricular conduction system. Am J Anat 1963; 113: 407-15.
[http://dx.doi.org/10.1002/aja.1001130305] [PMID: 14072365]
[58]
Lev M. The normal anatomy of the conduction system in man and its pathology in atrioventricular block. Ann N Y Acad Sci 1964; 111: 817-29.
[http://dx.doi.org/10.1111/j.1749-6632.1964.tb53149.x] [PMID: 14206801]
[59]
Watt TB Jr, Murao S, Pruitt RD. Left axis deviation induced experimentally in a primate heart. Am Heart J 1965; 70: 381-9.
[http://dx.doi.org/10.1016/0002-8703(65)90186-9] [PMID: 14330994]
[60]
Lev M. The conduction system Luisada, AA: Development and structure of the Cardiovascular System. Mc Graw-Hill 1968.
[61]
Roberts JT. The Conduction SystemDevelopment and structure of the Cardiovascular System. Mc Graw-Hill 1961.
[62]
Truex RC. Comparative anatomy and functional considerations of the cardiac conduction system Paes de Carvalho A, de Mello C, Hoffman B The specialized tissues of the heart. Amsterdam, London, New York: Elsevier Publ Co 1961; pp. 22-43.
[63]
Truex RC. Anatomy of the specialized tissues of the heart.Cardiac Arrhythmias. The Twenty Fifth Hannemann Symposium Eds.. Dreifus L, Likoff W”, Grune Stratton New York 1973.
[64]
Sugiura M, Okada R, Hiraoka K, Okawa S. Histological studies on the conduction system in 14 cases of right bundle branch block associated with left axis deviation. Jpn Heart J 1969; 10(2): 121-32.
[http://dx.doi.org/10.1536/ihj.10.121] [PMID: 5305685]
[65]
Wilson FN, Johnston FD, Hill IGW. The form of the electrocardiogram in experimental myocardial infarction. IV. Additional observations on the later effects produced by ligation of the anterior descending branch of the left coronary artery. Am Heart J 1935; 10: 1025-41.
[http://dx.doi.org/10.1016/S0002-8703(35)90381-7]
[66]
Hudson REB. Cardiovascular Pathology. London: Edward Arnold Pub Ltd. 1965; p. 1.

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