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Perspective

目前体外治疗SARS-CoV-2的数据

卷 27, 期 27, 2020

页: [4542 - 4548] 页: 7

弟呕挨: 10.2174/0929867327666200513075430

价格: $65

摘要

背景:2019年12月，我国出现新型冠状病毒SARS-CoV-2 (SARS-CoV-2)，武汉地区率先出现肺炎疫情，随后向全球传播。由于缺乏有效和具体的治疗方法，以及需要控制这一流行病，重新利用药物似乎是找到治疗性解决办法的最有效工具。 目的:本研究的目的是总结目前全世界用于体外治疗SARS-CoV-2的药物的数据。 方法:通过MEDLINE、EMBASE和Cochrane图书馆检索2000年1月至2020年4月的文献，评估目前或推定的SARS-CoV-2体外治疗的数据。 结果:虽然体外研究很少，但关于氯喹、羟基氯喹、瑞德西韦、硝唑奈德、替考拉宁、伊维菌素、洛匹那韦、高三尖杉酯碱和吐根碱的数据似乎很有前景。 结论:世界各地的科学家应该共同努力，加强努力，以找到可行和有效的解决方案，以应对这一新的全球病毒威胁。

关键词: SARS-CoV-2 (COVID-19)，体外研究，绿猴肾细胞株，疫苗，ACE2受体。

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