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Review Article

聚氯乙烯的表面改性，用于制造高级导管

卷 27, 期 10, 2020

页: [1616 - 1633] 页: 18

弟呕挨: 10.2174/0929867327666200227152150

价格: $65

摘要

聚合材料由于其出色的理化特性和多功能性而被发现可用于多个领域，包括用于组织再生，修复（假体，人工瓣膜），医疗设备，受控药物输送系统等的生物材料。医疗设备及其应用非常重要在现代医学中，开发具有改善的性能的新材料或改善现有材料的需求每天都在增加。为了获得不具有诸如结构破坏，钙化，感染或血栓形成之类的缺点的材料/表面，在这一领域激活了许多研究。由于其独特的性能，可用性和低成本，最常用的材料之一是聚氯乙烯（PVC）。获得满足医疗用途要求的管状装置的最常用方法是在不改变其物理和机械性能的情况下对聚合物进行表面改性。 PVC是疏水性聚合物，因此进行了许多研究，目的是通过化学改性来提高表面的亲水性，从而改善生物相容性，增强润湿性，减少摩擦或制造润滑性或抗菌性涂层。通过连续应用多种技术以获得所需的改性/性能，可以通过几种策略在一个步骤中，或者在某些情况下，在两个或多个步骤中实现PVC的表面改性。用于修饰PVC设备表面的最常见方法是：等离子体处理，电晕放电，化学接枝，放电，金属气相沉积，火焰处理，直接化学修饰（氧化，水解等），甚至某些物理修饰表面的粗糙度。

关键词: 导管，聚氯乙烯，表面改性，生物材料，抗生物膜表面，化学改性。

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