Search Result "pyrimidin-2(1H)-ones"


Research Article

Discovery of N-Phenyl-4-(1H-pyrrol-3-yl)pyrimidin-2-amine Derivatives as Potent Mnk2 Inhibitors: Design, Synthesis, SAR Analysis, and Evaluation of in vitro Anti-leukaemic Activity

Journal: Medicinal Chemistry
Volume: 15 Issue: 6 Year: 2019 Page: 602-623
Author(s): Ahmed M. Abdelaziz,Sarah Diab,Saiful Islam,Sunita K.C. Basnet,Benjamin Noll,Peng Li,Laychiluh B. Mekonnen,Jingfeng Lu,Hugo Albrecht,Robert W. Milne,Cobus Gerber,Mingfeng Yu,Shudong Wang

4-Thiophenoxy-N-(3,4,5-Trialkoxyphenyl)Pyrimidine-2-Amines as Potent and Selective Inhibitors of the T-Cell Tyrosine Kinase p56lck

Journal: Current Medicinal Chemistry
Volume: 11 Issue: 6 Year: 2004 Page: 747-753
Author(s): D. F.C. Moffat, R. A. Allen, S. E. Rapecki, P. D. Davis, J. OConnell, M. C. Hutchings, M. A. King, B. A. Boyce, M. J. Perry

Research Article

Synthesis of Novel 2-Amino-substituted 6-Methyl-pyrimidin-4-ol Derivatives and Their Biological Evaluation

Journal: Letters in Organic Chemistry
Volume: 16 Issue: 7 Year: 2019 Page: 575-583
Author(s): Aleksandr P. Yengoyan,Vergush A. Pivazyan,Emma A. Ghazaryan,Zhermen A. Azaryan

Synthesis of 4-amino-5-cyano-2, 6-Disubstituted Pyrimidines as a Potential Antifilarial DNA Topoisomerase II Inhibitors

Journal: Medicinal Chemistry
Volume: 4 Issue: 6 Year: 2008 Page: 577-585
Author(s): Ashok Kumar, J. K. Saxena, Prem M.S. Chauhan

Research Article

1, 2, 4-triazoles Clubbed Pyrimidine Compounds with Synthesis, Antimicrobial, Antituberculosis, Antimalarial, and Anti-protozoal Studies

Journal: Letters in Organic Chemistry
Volume: 18 Issue: 8 Year: 2021 Page: 617-624
Author(s): Navin B. Patel,Hetal I. Soni,Rahul B. Parmar,Manuel J. Chan-Bacab,Gildardo Rivera

Research Article

Poly(4-vinylpyridine) Catalyzed Synthesis and Characterization of Pyrano[2,3-d]pyrimidine Derivatives as Potent Antibacterial Agents

Journal: Current Bioactive Compounds
Volume: 14 Issue: 1 Year: 2018 Page: 54-59
Author(s): Tayebeh S. Mokhtari,Mohammad A. Amrollahi,Enayatollah Sheikhhosseini,Hassan Sheibani,Shahla S. Nezhad

Research Article

Design and Synthesis of Indole Pyrimidine Scaffolds as Potential KSP Inhibitors and Anticancer Agents

Journal: Current Enzyme Inhibition
Volume: 15 Issue: 1 Year: 2019 Page: 28-35
Author(s): Radhika Chelamalla,Ajitha Makula

6-Acetyl-5H-thiazolo[3,2-a]pyrimidine Derivatives as the Novel Acetylcholinesterase Inhibitors: Design, Synthesis, and Biological Activity

Journal: Medicinal Chemistry
Volume: 9 Issue: 5 Year: 2013 Page: 703-709
Author(s): Hui Zhi,Can Zhang,Zhixin Cheng,Zhe Jin,Erfang Huang,Shuo Li,Huangquan Lin,David Chicheong Wan,Chun Hu

Research Article

Development of New IDO Inhibitors with Coumarin Pyrimidine Scaffolds as the Potential Anti Cancer Agents

Journal: Current Bioactive Compounds
Volume: 16 Issue: 8 Year: 2020 Page: 1172-1180
Author(s): Radhika Chelamalla,Ajitha Makula

Research Article

Synthesis and Antimicrobial Evaluation of Some Novel Pyrimidine, Pyrazole, Chromene and Tetrahydrobenzo[b]thiophene Derivatives Bearing Pyrimidinthione Moiety

Journal: Current Organic Synthesis
Volume: 17 Issue: 7 Year: 2020 Page: 548-557
Author(s): Mohamed Ahmed Mahmoud Abdel Reheim,Ibrahim Saad Abdel Hafiz,Mohamed Ahmed Elian

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